Effectiveness of Rituximab in Severe Wegener's Granulomatosis

We hereby describe the satisfactory evolution of rituximab treatment in two patients with Wegener's granulomatosis (WG). Rituximab was indicated for refractoriness to standard treatment in one case and life-threatening myelotoxicity due to alkylating agents in the other. A brief review of previ...

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Detalles Bibliográficos
Autores: Oristrell Salvà, Joaquín|||0000-0003-1486-3192, Bejarano, Guillermina, Jordana, Rosa|||0000-0002-2632-7672, Monteagudo, Manuel, Marí, Begoña|||0000-0001-9212-2600, Casanovas, Arnau, Tolosa, Carles
Tipo de recurso: artículo
Fecha de publicación:2009
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:183214
Acceso en línea:https://ddd.uab.cat/record/183214
https://dx.doi.org/urn:doi:10.2174/1874306400903010094
Access Level:acceso abierto
Palabra clave:Rituximab
Wegener's granulomatosis
Rescue treatment
Descripción
Sumario:We hereby describe the satisfactory evolution of rituximab treatment in two patients with Wegener's granulomatosis (WG). Rituximab was indicated for refractoriness to standard treatment in one case and life-threatening myelotoxicity due to alkylating agents in the other. A brief review of previous experience with the use of rituximab in the treatment of WG is presented.