Differences in fatty acids composition between Plasmodium infected and uninfected house sparrows along an urbanization gradient

Anthropogenic activities such as intensification of agriculture, animal husbandry and expansion of cities can negatively impact wildlife through its influence on the availability of high-quality food resources and pathogen transmission. The house sparrow (Passer domesticus), an urban exploiter, is u...

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Autores: Jiménez-Peñuela, Jessica, Ferraguti, Martina, Martínez de la Puente, Josué, Soriguer, Ramón C., Figuerola, Jordi, Isaksson, Caroline
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/258089
Acceso en línea:http://hdl.handle.net/10261/258089
Access Level:acceso abierto
Palabra clave:Avian malaria
Immune responses
Passer domesticus
PUFA
Omega-3
Omega-6
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spelling Differences in fatty acids composition between Plasmodium infected and uninfected house sparrows along an urbanization gradientJiménez-Peñuela, JessicaFerraguti, MartinaMartínez de la Puente, JosuéSoriguer, Ramón C.Figuerola, JordiIsaksson, CarolineAvian malariaImmune responsesPasser domesticusPUFAOmega-3Omega-6Anthropogenic activities such as intensification of agriculture, animal husbandry and expansion of cities can negatively impact wildlife through its influence on the availability of high-quality food resources and pathogen transmission. The house sparrow (Passer domesticus), an urban exploiter, is undergoing a population decline. Nutritional constrains and infectious diseases has been highlighted as potential causes. Fatty acids (FAs) play an important role in modulating certain immune responses needed to combat parasite infections. FAs are highly influenced by dietary availability and have been shown to vary between urban and rural birds. Habitat anthropization also affects avian malaria epidemiology but little attention has been given to the relationship between blood parasite infection, host FAs composition and anthropization. Here, we analysed 165 juvenile birds either infected by Plasmodium or uninfected, captured at 15 localities grouped in triplets containing urban, rural and natural habitats. The total level of FAs was higher in birds from urban than from rural habitats, suggesting a greater availability of fat-rich foods sources. Furthermore, Plasmodium infected birds had higher relative levels of ω-3 polyunsaturated fatty acids (PUFAs) but lower of ω-6 PUFAs than uninfected birds. In concordance, the ω-6/ω-3 ratio was also lower in infected than in uninfected birds, but only from natural habitats, likely driven by the slightly higher ω-3 PUFAs in infected birds from natural habitats. Birds from anthropized environments may metabolize the ω-3 PUFAs to promote anti-inflammatory responses against stressors, which would result in lower ω-3 affecting their response against Plasmodium. Alternatively, lower ω-6 PUFAs may influence birds susceptibility to infection due to a weaker pro-inflammatory response. These descriptive results do not allow us to identify the causality of these associations but highlight the need to further investigate the relevance of FAs for birds to fight infectious diseases in habitats with different degree of urbanization.Peer reviewedElsevierJunta de AndalucíaMinisterio de Ciencia e Innovación (España)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202220222022info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/258089reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/MICIU/PGC2018-095704-B-I00 and PID2020-118205GBI00/http://dx.doi.org/10.1016/j.scitotenv.2021.152664Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/2580892026-05-22T06:33:51Z
dc.title.none.fl_str_mv Differences in fatty acids composition between Plasmodium infected and uninfected house sparrows along an urbanization gradient
title Differences in fatty acids composition between Plasmodium infected and uninfected house sparrows along an urbanization gradient
spellingShingle Differences in fatty acids composition between Plasmodium infected and uninfected house sparrows along an urbanization gradient
Jiménez-Peñuela, Jessica
Avian malaria
Immune responses
Passer domesticus
PUFA
Omega-3
Omega-6
title_short Differences in fatty acids composition between Plasmodium infected and uninfected house sparrows along an urbanization gradient
title_full Differences in fatty acids composition between Plasmodium infected and uninfected house sparrows along an urbanization gradient
title_fullStr Differences in fatty acids composition between Plasmodium infected and uninfected house sparrows along an urbanization gradient
title_full_unstemmed Differences in fatty acids composition between Plasmodium infected and uninfected house sparrows along an urbanization gradient
title_sort Differences in fatty acids composition between Plasmodium infected and uninfected house sparrows along an urbanization gradient
dc.creator.none.fl_str_mv Jiménez-Peñuela, Jessica
Ferraguti, Martina
Martínez de la Puente, Josué
Soriguer, Ramón C.
Figuerola, Jordi
Isaksson, Caroline
author Jiménez-Peñuela, Jessica
author_facet Jiménez-Peñuela, Jessica
Ferraguti, Martina
Martínez de la Puente, Josué
Soriguer, Ramón C.
Figuerola, Jordi
Isaksson, Caroline
author_role author
author2 Ferraguti, Martina
Martínez de la Puente, Josué
Soriguer, Ramón C.
Figuerola, Jordi
Isaksson, Caroline
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Junta de Andalucía
Ministerio de Ciencia e Innovación (España)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Avian malaria
Immune responses
Passer domesticus
PUFA
Omega-3
Omega-6
topic Avian malaria
Immune responses
Passer domesticus
PUFA
Omega-3
Omega-6
description Anthropogenic activities such as intensification of agriculture, animal husbandry and expansion of cities can negatively impact wildlife through its influence on the availability of high-quality food resources and pathogen transmission. The house sparrow (Passer domesticus), an urban exploiter, is undergoing a population decline. Nutritional constrains and infectious diseases has been highlighted as potential causes. Fatty acids (FAs) play an important role in modulating certain immune responses needed to combat parasite infections. FAs are highly influenced by dietary availability and have been shown to vary between urban and rural birds. Habitat anthropization also affects avian malaria epidemiology but little attention has been given to the relationship between blood parasite infection, host FAs composition and anthropization. Here, we analysed 165 juvenile birds either infected by Plasmodium or uninfected, captured at 15 localities grouped in triplets containing urban, rural and natural habitats. The total level of FAs was higher in birds from urban than from rural habitats, suggesting a greater availability of fat-rich foods sources. Furthermore, Plasmodium infected birds had higher relative levels of ω-3 polyunsaturated fatty acids (PUFAs) but lower of ω-6 PUFAs than uninfected birds. In concordance, the ω-6/ω-3 ratio was also lower in infected than in uninfected birds, but only from natural habitats, likely driven by the slightly higher ω-3 PUFAs in infected birds from natural habitats. Birds from anthropized environments may metabolize the ω-3 PUFAs to promote anti-inflammatory responses against stressors, which would result in lower ω-3 affecting their response against Plasmodium. Alternatively, lower ω-6 PUFAs may influence birds susceptibility to infection due to a weaker pro-inflammatory response. These descriptive results do not allow us to identify the causality of these associations but highlight the need to further investigate the relevance of FAs for birds to fight infectious diseases in habitats with different degree of urbanization.
publishDate 2022
dc.date.none.fl_str_mv 2022
2022
2022
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/258089
url http://hdl.handle.net/10261/258089
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/MICIU/PGC2018-095704-B-I00 and PID2020-118205GBI00/
http://dx.doi.org/10.1016/j.scitotenv.2021.152664
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.812429

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