Assessment of lutein and zeaxanthin status and dietary markers as predictors of the contrast threshold in 2 age groups of men and women

Lutein and zeaxanthin (L + Z) status is associated with the macular pigment (MP). The relationship between MP and visual function is controversial. We hypothesized that, within the framework of nutrition, visual function was related to MP and nutritional and/or/dietary factors influencing it. A cros...

Descripción completa

Detalles Bibliográficos
Autores: Estévez Santiago, Rocío, Olmedilla-Alonso, Begoña, Beltrán de Miguel, Beatriz
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2016
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/171504
Acceso en línea:http://hdl.handle.net/10261/171504
Access Level:acceso abierto
Palabra clave:Macular pigment
Cross-sectional study
Age groups
Fruits/vegetables
Lutein/zeaxanthin
Contrast threshold
id ES_65ac0169ccb7ed186c19668a01753cb8
oai_identifier_str oai:digital.csic.es:10261/171504
network_acronym_str ES
network_name_str España
repository_id_str
spelling Assessment of lutein and zeaxanthin status and dietary markers as predictors of the contrast threshold in 2 age groups of men and womenEstévez Santiago, RocíoOlmedilla-Alonso, BegoñaBeltrán de Miguel, BeatrizMacular pigmentCross-sectional studyAge groupsFruits/vegetablesLutein/zeaxanthinContrast thresholdLutein and zeaxanthin (L + Z) status is associated with the macular pigment (MP). The relationship between MP and visual function is controversial. We hypothesized that, within the framework of nutrition, visual function was related to MP and nutritional and/or/dietary factors influencing it. A cross-sectional study was performed in 108 volunteers divided into 2 age groups (20-35 years; 45-65 years), each 27 women and 27 men, to assess the relationship between MP optical density (MPOD) and contrast threshold (CT), considering the influence of L + Z and, fruit and vegetable (F + V) intake. MPOD, L + Z in serum and dietary intake were determined using heterochromatic flicker photometry, high-performance liquid chromatography and 3-day food records, respectively. CT was measured with the CGT-1000 Contrast Glaretester at 6 stimulus sizes, with and without glare. Spearman correlation coefficient and a generalized linear model were used for the statistical study. MPOD and CT were higher and lower, respectively in younger than in elder individuals (P < .000) and were correlated only in the older group. CT were higher under glare conditions, at the intermediate and smaller visual angles, with greater differences in the older (P < .003) than the younger group (P < .014). In the total sample, CT correlated inversely with MPOD (correlation coefficients and P values ranging from -.245 to -.152 and from .000 to .026, respectively) and directly with F + V intake (correlation coefficients and P values ranging from -.265 to -.176 and from .000 to .010, respectively). As predictors of CT in the total sample, MPOD, F + V (every 100 g/d) and sex were identified (β coefficients ranged from -0.01 to -1.86; from 0.01 to 0.08 and from 0.01 to 0.40, respectively). CT revealed age-specific nutritional predictors: MPOD and serum lutein in the 45- to 65-year group, and F + V intake in the 20- to 35-year group.This study was supported by a grant from the Instituto de Salud Carlos III (Ministerio de Ciencia e Innovación Tecnológica, Spain) (grant no. PS09/00681), and Rocío Estévez-Santiago is the recipient of a JAE-Predoc grant from the Consejo Superior de Investigaciones Científicas (CSIC), awarded under the program of the Junta para la Ampliación de Estudios, co-financed by the European Social Fund.Peer ReviewedElsevierInstituto de Salud Carlos IIIMinisterio de Ciencia e Innovación (España)European CommissionConsejo Superior de Investigaciones Científicas (España)Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]2018201820162018info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Postprintinfo:eu-repo/semantics/acceptedVersionhttp://hdl.handle.net/10261/171504reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttps://doi.org/10.1016/j.nutres.2016.02.007Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/1715042026-05-22T06:33:51Z
dc.title.none.fl_str_mv Assessment of lutein and zeaxanthin status and dietary markers as predictors of the contrast threshold in 2 age groups of men and women
title Assessment of lutein and zeaxanthin status and dietary markers as predictors of the contrast threshold in 2 age groups of men and women
spellingShingle Assessment of lutein and zeaxanthin status and dietary markers as predictors of the contrast threshold in 2 age groups of men and women
Estévez Santiago, Rocío
Macular pigment
Cross-sectional study
Age groups
Fruits/vegetables
Lutein/zeaxanthin
Contrast threshold
title_short Assessment of lutein and zeaxanthin status and dietary markers as predictors of the contrast threshold in 2 age groups of men and women
title_full Assessment of lutein and zeaxanthin status and dietary markers as predictors of the contrast threshold in 2 age groups of men and women
title_fullStr Assessment of lutein and zeaxanthin status and dietary markers as predictors of the contrast threshold in 2 age groups of men and women
title_full_unstemmed Assessment of lutein and zeaxanthin status and dietary markers as predictors of the contrast threshold in 2 age groups of men and women
title_sort Assessment of lutein and zeaxanthin status and dietary markers as predictors of the contrast threshold in 2 age groups of men and women
dc.creator.none.fl_str_mv Estévez Santiago, Rocío
Olmedilla-Alonso, Begoña
Beltrán de Miguel, Beatriz
author Estévez Santiago, Rocío
author_facet Estévez Santiago, Rocío
Olmedilla-Alonso, Begoña
Beltrán de Miguel, Beatriz
author_role author
author2 Olmedilla-Alonso, Begoña
Beltrán de Miguel, Beatriz
author2_role author
author
dc.contributor.none.fl_str_mv Instituto de Salud Carlos III
Ministerio de Ciencia e Innovación (España)
European Commission
Consejo Superior de Investigaciones Científicas (España)
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Macular pigment
Cross-sectional study
Age groups
Fruits/vegetables
Lutein/zeaxanthin
Contrast threshold
topic Macular pigment
Cross-sectional study
Age groups
Fruits/vegetables
Lutein/zeaxanthin
Contrast threshold
description Lutein and zeaxanthin (L + Z) status is associated with the macular pigment (MP). The relationship between MP and visual function is controversial. We hypothesized that, within the framework of nutrition, visual function was related to MP and nutritional and/or/dietary factors influencing it. A cross-sectional study was performed in 108 volunteers divided into 2 age groups (20-35 years; 45-65 years), each 27 women and 27 men, to assess the relationship between MP optical density (MPOD) and contrast threshold (CT), considering the influence of L + Z and, fruit and vegetable (F + V) intake. MPOD, L + Z in serum and dietary intake were determined using heterochromatic flicker photometry, high-performance liquid chromatography and 3-day food records, respectively. CT was measured with the CGT-1000 Contrast Glaretester at 6 stimulus sizes, with and without glare. Spearman correlation coefficient and a generalized linear model were used for the statistical study. MPOD and CT were higher and lower, respectively in younger than in elder individuals (P < .000) and were correlated only in the older group. CT were higher under glare conditions, at the intermediate and smaller visual angles, with greater differences in the older (P < .003) than the younger group (P < .014). In the total sample, CT correlated inversely with MPOD (correlation coefficients and P values ranging from -.245 to -.152 and from .000 to .026, respectively) and directly with F + V intake (correlation coefficients and P values ranging from -.265 to -.176 and from .000 to .010, respectively). As predictors of CT in the total sample, MPOD, F + V (every 100 g/d) and sex were identified (β coefficients ranged from -0.01 to -1.86; from 0.01 to 0.08 and from 0.01 to 0.40, respectively). CT revealed age-specific nutritional predictors: MPOD and serum lutein in the 45- to 65-year group, and F + V intake in the 20- to 35-year group.
publishDate 2016
dc.date.none.fl_str_mv 2016
2018
2018
2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Postprint
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/171504
url http://hdl.handle.net/10261/171504
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://doi.org/10.1016/j.nutres.2016.02.007
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869409759732432896
score 15.812429

Similares en LA Referencia