Fine Particulate Air Pollution and Mortality: Response to Enstrom's Reanalysis of the American Cancer Society Cancer Prevention Study II Cohort

The first analysis of long-term exposures to air pollution and risk of mortality using the American Cancer Society Cancer Prevention Study II (ACS CPS-II) cohort was published in 1995.1 Subsequently, extensive independent reanalysis2 and multiple extended analyses3-7 were conducted. These studies ha...

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Bibliographic Details
Authors: Pope, C. Arden, Krewski, Daniel, Gapstur, Susan M., Turner, Michelle C., Jerrett, Michael, Burnett, Richard T.
Format: article
Status:Published version
Publication Date:2017
Country:España
Institution:Universidad de Barcelona
Repository:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/119653
Online Access:https://hdl.handle.net/2445/119653
Access Level:Open access
Keyword:Contaminació atmosfèrica
Mortalitat
Atmospheric pollution
Mortality
Description
Summary:The first analysis of long-term exposures to air pollution and risk of mortality using the American Cancer Society Cancer Prevention Study II (ACS CPS-II) cohort was published in 1995.1 Subsequently, extensive independent reanalysis2 and multiple extended analyses3-7 were conducted. These studies have consistently demonstrated that exposure to fine particulate matter air pollution (PM2.5) is associated with increased risk of mortality, especially cardiopulmonary or cardiovascular disease mortality. A recent analysis by Enstrom, based on early data from the ACS CPS-II cohort, reports no significant relationship between PM2.5 and total mortality.8 The author asserts that the original analyses, reanalyses, and the extended analyses found positive PM2.5–mortality relationships because of selective use of CPS-II and PM2.5 data.