Evaluation of Intraocular Pressure and Other Biomechanical Parameters to Distinguish between Subclinical Keratoconus and Healthy Corneas

(1) Purpose: To assess the main corneal response differences between normal and subclinical keratoconus (SCKC) with a Corvis(R) ST device. (2) Material and Methods: We selected 183 eyes of normal patients, of a mean age of 33 +/- 9 years and 16 eyes of patients with SCKC of a similar mean age. We me...

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Detalles Bibliográficos
Autores: Peris-Martínez C, Díez-Ajenjo MA, García-Domene MC, Pinazo-Durán MD, Luque-Cobija MJ, Del Buey-Sayas MÁ, Ortí-Navarro S
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2021
País:España
Institución:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repositorio:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:fisabio.fundanetsuite.com:p9399
Acceso en línea:https://fisabio.portalinvestigacion.com/publicaciones/9399
Access Level:acceso abierto
Palabra clave:intraocular pressure
ocular inflammation
cornea biomechanics
Corvis(&#174)
ST
subclinical keratoconus
Descripción
Sumario:(1) Purpose: To assess the main corneal response differences between normal and subclinical keratoconus (SCKC) with a Corvis(R) ST device. (2) Material and Methods: We selected 183 eyes of normal patients, of a mean age of 33 +/- 9 years and 16 eyes of patients with SCKC of a similar mean age. We measured best corrected visual acuity (BCVA) and corneal topography with a Pentacam HD device to select the SCKC group. Biomechanical measurements were performed using the Corvis(R) ST device. We carried out a non-parametric analysis of the data with SPSS software (Wilcoxon signed rank-test). (3) Results: We found statistically significant differences between the control and SCKC groups in some corneal biomechanical parameters: first and second applanation time (p = 0.05 and p = 0.02), maximum deformation amplitude (p = 0.016), highest concavity radius (p = 0.007), and second applanation length and corneal velocity ((p = 0.039 and p = 0.016). (4) Conclusions: Our results show that the use of normalised biomechanical parameters provided by noncontact tonometry, combined with a discriminant function theory, is a useful tool for detecting subclinical keratoconus.