Pandemic influenza A (H1N1) infection in pregnant and nonpregnant women in Spain (2009-2010)

The present study aimed to compare the main features of infection with pandemic influenza A virus in pregnant and nonpregnant women admitted to hospitals in Spain during the first waves of the 2009-2010 influenza pandemic. This was a prospective (November 2009 to June 2010), multicenter observationa...

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Detalles Bibliográficos
Autores: Morales Suárez-Varela, María, González Candelas, Fernando, Astray, Jenaro, Alonso, Jordi, Garín, Olatz, Castro Acosta, Ady Angélica, Galán, Juan Carlos, Baricot, Maretva, Castilla, Jesús, Godoy i García, Pere, Delgado Rodríguez, Miguel, Martín Sánchez, Vicente, Mayoral, José María, Pumarola Suñé, Tomàs, Quintana, José María, Tamames, Sonia, Llopis González, Agustín, Domínguez García, Àngela, CIBERESP Cases and Controls in Pandemic Influenza Working Group, Controls in Pandemic Influenza Working Group
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/59229
Acceso en línea:https://hdl.handle.net/2445/59229
Access Level:acceso abierto
Palabra clave:Influenzavirus
Dones
Embarassades
Influenza viruses
Women
Pregnant women
Descripción
Sumario:The present study aimed to compare the main features of infection with pandemic influenza A virus in pregnant and nonpregnant women admitted to hospitals in Spain during the first waves of the 2009-2010 influenza pandemic. This was a prospective (November 2009 to June 2010), multicenter observational study. All cases were women of reproductive age who had not been vaccinated against seasonal or pandemic influenza A. Influenza infection was confirmed by reverse transcription-polymerase chain reaction (RT-PCR). The sociodemographic and clinical data of all cases were reviewed. A total of 219 inpatients, including 49 pregnant women and 170 nonpregnant women, were enrolled in the study upon admission to participating hospitals. The most substantially different symptoms between the groups were respiratory distress and unilobar consolidation, both of which were more frequent among nonpregnant women. Antibiotics and systemic corticosteroids were more frequently used in nonpregnant women; however, there were no differences in the rates of treatment with antivirals. Our findings indicated that the compared with nonpregnant women, pregnant women in this study did not have significantly different symptoms and were not at increased risk of complications from pandemic influenza virus infection.

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