The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge?

[Background & Aims]: Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent, yet largely underappreciated liver condition which is closely associated with obesity and metabolic disease. Despite affecting an estimated 1 in 4 adults globally, NAFLD is largely absent on national and global...

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Autores: Lazarus, Jeffrey V., Mark, Henry E., Villota-Rivas, Marcela, Palayew, Adam, Carrieri, Patrizia, Colombo, Massimo, Ekstedt, Mattias, Esmat, Gamal, George, Jacob, Marchesini, Giulio, Novak, Katja, Ocama, Ponsiano, Ratziu, Vlad, Razavi, Homie, Romero-Gómez, Manuel, Silva, Marcelo, Spearman, C. Wendy, Tacke, Frank, Tsochatzis, Emmanuel A., Yilmaz, Yusuf, Younossi, Zobair M., Wong, Vincent Wai-Sun, Zelber-Sagi, Shira, Cortez-Pinto, Helena, Anstee, Quentin M., NAFLD
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/307324
Acceso en línea:http://hdl.handle.net/10261/307324
https://api.elsevier.com/content/abstract/scopus_id/85122443139
Access Level:acceso abierto
Palabra clave:Non-alcoholic fatty liver disease
Non-alcoholic steatohepatitis
Liver health
Global public health
Policy preparednesss
Health policies
Multiple correspondence analysis
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
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repository_id_str
spelling The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge?Lazarus, Jeffrey V.Mark, Henry E.Villota-Rivas, MarcelaPalayew, AdamCarrieri, PatriziaColombo, MassimoEkstedt, MattiasEsmat, GamalGeorge, JacobMarchesini, GiulioNovak, KatjaOcama, PonsianoRatziu, VladRazavi, HomieRomero-Gómez, ManuelSilva, MarceloSpearman, C. WendyTacke, FrankTsochatzis, Emmanuel A.Yilmaz, YusufYounossi, Zobair M.Wong, Vincent Wai-SunZelber-Sagi, ShiraCortez-Pinto, HelenaAnstee, Quentin M.NAFLDNon-alcoholic fatty liver diseaseNon-alcoholic steatohepatitisLiver healthGlobal public healthPolicy preparednesssHealth policiesMultiple correspondence analysishttp://metadata.un.org/sdg/3Ensure healthy lives and promote well-being for all at all ages[Background & Aims]: Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent, yet largely underappreciated liver condition which is closely associated with obesity and metabolic disease. Despite affecting an estimated 1 in 4 adults globally, NAFLD is largely absent on national and global health agendas.[Methods]: We collected data from 102 countries, accounting for 86% of the world population, on NAFLD policies, guidelines, civil society engagement, clinical management, and epidemiologic data. A preparedness index was developed by coding questions into 6 domains (policies, guidelines, civil awareness, epidemiology and data, NAFLD detection, and NAFLD care management) and categorising the responses as high, medium, and low; a multiple correspondence analysis was then applied.[Results]: The highest scoring countries were India (42.7) and the United Kingdom (40.0), with 32 countries (31%) scoring zero out of 100. For 5 of the domains a minority of countries were categorised as high-level while the majority were categorised as low-level. No country had a national or sub-national strategy for NAFLD and <2% of the different strategies for related conditions included any mention of NAFLD. National NAFLD clinical guidelines were present in only 32 countries.[Conclusions]: Although NAFLD is a pressing public health problem, no country was found to be well prepared to address it. There is a pressing need for strategies to address NAFLD at national and global levels.The data collection and analysis were funded by the EASL International Liver Foundation with support from, Intercept, Bristol-Myers-Squibb Company, Genfit, and MSD. Data collection for the original European data was funded by the EASL International Liver Foundation supported by Gilead Sciences Europe Ltd., Allergan Pharmaceutical International Ltd., Bristol-Myers-Squibb Company, Pfizer Inc., and Resoundant Inc.Peer reviewedElsevierEASL International Liver FoundationBristol-Myers SquibbGenfitMSDGilead SciencesAllergan FoundationPfizerResoundantLazarus, Jeffrey V. [0000-0001-9618-2299]Mark, Henry E. [0000-0002-8022-4279]Ekstedt, Mattias [0000-0002-5590-8601]George, Jacob [0000-0002-8421-5476]Marchesini, Giulio [0000-0003-2407-9860]Spearman, C. Wendy [0000-0003-3199-301X]Tacke, Frank [0000-0001-6206-0226]Yilmaz, Yusuf [0000-0003-4518-5283]Wong, Vincent Wai-Sun [0000-0003-2215-9410]Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202320232022info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501application/pdfhttp://hdl.handle.net/10261/307324https://api.elsevier.com/content/abstract/scopus_id/85122443139reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Ingléshttps://doi.org/10.1016/j.jhep.2021.10.025Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3073242026-05-22T06:33:51Z
dc.title.none.fl_str_mv The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge?
title The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge?
spellingShingle The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge?
Lazarus, Jeffrey V.
Non-alcoholic fatty liver disease
Non-alcoholic steatohepatitis
Liver health
Global public health
Policy preparednesss
Health policies
Multiple correspondence analysis
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
title_short The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge?
title_full The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge?
title_fullStr The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge?
title_full_unstemmed The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge?
title_sort The global NAFLD policy review and preparedness index: Are countries ready to address this silent public health challenge?
dc.creator.none.fl_str_mv Lazarus, Jeffrey V.
Mark, Henry E.
Villota-Rivas, Marcela
Palayew, Adam
Carrieri, Patrizia
Colombo, Massimo
Ekstedt, Mattias
Esmat, Gamal
George, Jacob
Marchesini, Giulio
Novak, Katja
Ocama, Ponsiano
Ratziu, Vlad
Razavi, Homie
Romero-Gómez, Manuel
Silva, Marcelo
Spearman, C. Wendy
Tacke, Frank
Tsochatzis, Emmanuel A.
Yilmaz, Yusuf
Younossi, Zobair M.
Wong, Vincent Wai-Sun
Zelber-Sagi, Shira
Cortez-Pinto, Helena
Anstee, Quentin M.
NAFLD
author Lazarus, Jeffrey V.
author_facet Lazarus, Jeffrey V.
Mark, Henry E.
Villota-Rivas, Marcela
Palayew, Adam
Carrieri, Patrizia
Colombo, Massimo
Ekstedt, Mattias
Esmat, Gamal
George, Jacob
Marchesini, Giulio
Novak, Katja
Ocama, Ponsiano
Ratziu, Vlad
Razavi, Homie
Romero-Gómez, Manuel
Silva, Marcelo
Spearman, C. Wendy
Tacke, Frank
Tsochatzis, Emmanuel A.
Yilmaz, Yusuf
Younossi, Zobair M.
Wong, Vincent Wai-Sun
Zelber-Sagi, Shira
Cortez-Pinto, Helena
Anstee, Quentin M.
NAFLD
author_role author
author2 Mark, Henry E.
Villota-Rivas, Marcela
Palayew, Adam
Carrieri, Patrizia
Colombo, Massimo
Ekstedt, Mattias
Esmat, Gamal
George, Jacob
Marchesini, Giulio
Novak, Katja
Ocama, Ponsiano
Ratziu, Vlad
Razavi, Homie
Romero-Gómez, Manuel
Silva, Marcelo
Spearman, C. Wendy
Tacke, Frank
Tsochatzis, Emmanuel A.
Yilmaz, Yusuf
Younossi, Zobair M.
Wong, Vincent Wai-Sun
Zelber-Sagi, Shira
Cortez-Pinto, Helena
Anstee, Quentin M.
NAFLD
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv EASL International Liver Foundation
Bristol-Myers Squibb
Genfit
MSD
Gilead Sciences
Allergan Foundation
Pfizer
Resoundant
Lazarus, Jeffrey V. [0000-0001-9618-2299]
Mark, Henry E. [0000-0002-8022-4279]
Ekstedt, Mattias [0000-0002-5590-8601]
George, Jacob [0000-0002-8421-5476]
Marchesini, Giulio [0000-0003-2407-9860]
Spearman, C. Wendy [0000-0003-3199-301X]
Tacke, Frank [0000-0001-6206-0226]
Yilmaz, Yusuf [0000-0003-4518-5283]
Wong, Vincent Wai-Sun [0000-0003-2215-9410]
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv Non-alcoholic fatty liver disease
Non-alcoholic steatohepatitis
Liver health
Global public health
Policy preparednesss
Health policies
Multiple correspondence analysis
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
topic Non-alcoholic fatty liver disease
Non-alcoholic steatohepatitis
Liver health
Global public health
Policy preparednesss
Health policies
Multiple correspondence analysis
http://metadata.un.org/sdg/3
Ensure healthy lives and promote well-being for all at all ages
description [Background & Aims]: Non-alcoholic fatty liver disease (NAFLD) is a highly prevalent, yet largely underappreciated liver condition which is closely associated with obesity and metabolic disease. Despite affecting an estimated 1 in 4 adults globally, NAFLD is largely absent on national and global health agendas.
publishDate 2022
dc.date.none.fl_str_mv 2022
2023
2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/307324
https://api.elsevier.com/content/abstract/scopus_id/85122443139
url http://hdl.handle.net/10261/307324
https://api.elsevier.com/content/abstract/scopus_id/85122443139
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv https://doi.org/10.1016/j.jhep.2021.10.025
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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