Generative adversarial networks for anonymized healthcare of lung cancer patients

The digital twin in health care is the dynamic digital representation of the patient’s anatomy and physiology through computational models which are continuously updated from clinical data. Furthermore, used in combination with machine learning technologies, it should help doctors in therapeutic pat...

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Detalles Bibliográficos
Autores: González Abril, Luis, Angulo Bahón, Cecilio|||0000-0001-9589-8199, Ortega Ramírez, Juan Antonio, López Guerra, José Luis
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/354398
Acceso en línea:https://hdl.handle.net/2117/354398
https://dx.doi.org/10.3390/electronics10182220
Access Level:acceso abierto
Palabra clave:Machine learning
Lungs--Cancer
Artificial intelligence
Digital twin
Anonymization
Generative adversarial network
Lung cancer
Xarxes neuronals (Informàtica) -- Aplicacions
Aprenentatge automàtic
Pulmons -- Càncer
Intel·ligència artificial
Àrees temàtiques de la UPC::Informàtica
Descripción
Sumario:The digital twin in health care is the dynamic digital representation of the patient’s anatomy and physiology through computational models which are continuously updated from clinical data. Furthermore, used in combination with machine learning technologies, it should help doctors in therapeutic path and in minimally invasive intervention procedures. Confidentiality of medical records is a very delicate issue, therefore some anonymization process is mandatory in order to maintain patients privacy. Moreover, data availability is very limited in some health domains like lung cancer treatment. Hence, generation of synthetic data conformed to real data would solve this issue. In this paper, the use of generative adversarial networks (GAN) for the generation of synthetic data of lung cancer patients is introduced as a tool to solve this problem in the form of anonymized synthetic patients. Generated synthetic patients are validated using both statistical methods, as well as by oncologists using the indirect mortality rate obtained for patients in different stages.