Acute heart failure and adverse events associated with the presence of renal dysfunction and hyperkalaemia. EAHFE- renal dysfunction and hyperkalaemia

Objective: To study the outcomes of patients with acute heart failure (AHF) presenting renal dysfunction (RD) or hyperkalaemia (Hk) alone or in combination. Method: We analysed the data of the EAHFE registry, a multicentre, non interventionist cohort with prospective follow-up of patients with AHF....

Descripción completa

Detalles Bibliográficos
Autores: Jacob, Javier, Llauger, Lluis, Herrero-Puente, Pablo, Martín-Sánchez, Francisco J., Llorens, Pere, Roset, Alex, Gil, Víctor, Fuentes, Marta, Lucas-Imbernón, Francisco Javier, Miró, Òscar, ICA-SEMES Research Group
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2019
País:España
Institución:Universitat Pompeu Fabra
Repositorio:Repositorio Digital de la UPF
OAI Identifier:oai:repositori.upf.edu:10230/43252
Acceso en línea:http://hdl.handle.net/10230/43252
http://dx.doi.org/10.1016/j.ejim.2019.07.010
Access Level:acceso abierto
Palabra clave:Acute heart failure
Hyperkalaemia
Outcomes
Renal dysfunction
id ES_633f6edacf3f4e6b8fd3dc96779467ba
oai_identifier_str oai:repositori.upf.edu:10230/43252
network_acronym_str ES
network_name_str España
repository_id_str
spelling Acute heart failure and adverse events associated with the presence of renal dysfunction and hyperkalaemia. EAHFE- renal dysfunction and hyperkalaemiaJacob, JavierLlauger, LluisHerrero-Puente, PabloMartín-Sánchez, Francisco J.Llorens, PereRoset, AlexGil, VíctorFuentes, MartaLucas-Imbernón, Francisco JavierMiró, ÒscarICA-SEMES Research GroupAcute heart failureHyperkalaemiaOutcomesRenal dysfunctionObjective: To study the outcomes of patients with acute heart failure (AHF) presenting renal dysfunction (RD) or hyperkalaemia (Hk) alone or in combination. Method: We analysed the data of the EAHFE registry, a multicentre, non interventionist cohort with prospective follow-up of patients with AHF. Four groups were defined based on the presence or not of RD or Hk alone or in combination. The primary endpoint was 30-day all-cause mortality. Results: A total of 11,935 of the 13,791 patients included in the EAHFE registry were analysed. Of these, 5088 (42.6%) did not have RD or Hk (NoRD-NoHk), 150 (1.3%) had no RD but had Hk (NoRD-Hk), 6012 (50.4%) had RD but not Hk (RD-NoHk) and 685 (5.7%) had both RD and Hk (RD-Hk). Thirty-day all-cause mortality was greatest in the RD-Hk group with an adjusted Hazard Ratio (HR) of 2.44 (confidence interval 95% [CI95%] 1.67-3.55; p < 0.001) and in the RD-NoHk group with an adjusted HR of 1.34 (CI95% 1.04-1.71; p = 0.022). There were no significant differences in in-hospital mortality and reconsultation at 30 days for HF. For the combined endpoint of 30-day all-cause mortality the adjusted HR was 1.33 (CI95% 1.04-1.70); (p = 0.021) for the RD-Hk group. Conclusions: The association of 30-day all-cause mortality with the presence of RD and Hk in patients presenting AHF at admission is greater than in those without this combination.Elsevier20202019info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersionapplication/pdfapplication/pdfhttp://hdl.handle.net/10230/43252http://dx.doi.org/10.1016/j.ejim.2019.07.010reponame:Repositorio Digital de la UPFinstname:Universitat Pompeu FabraInglés© Elsevier http://dx.doi.org/10.1016/j.ejim.2019.07.010info:eu-repo/semantics/openAccessoai:repositori.upf.edu:10230/432522026-06-12T07:21:37Z
dc.title.none.fl_str_mv Acute heart failure and adverse events associated with the presence of renal dysfunction and hyperkalaemia. EAHFE- renal dysfunction and hyperkalaemia
title Acute heart failure and adverse events associated with the presence of renal dysfunction and hyperkalaemia. EAHFE- renal dysfunction and hyperkalaemia
spellingShingle Acute heart failure and adverse events associated with the presence of renal dysfunction and hyperkalaemia. EAHFE- renal dysfunction and hyperkalaemia
Jacob, Javier
Acute heart failure
Hyperkalaemia
Outcomes
Renal dysfunction
title_short Acute heart failure and adverse events associated with the presence of renal dysfunction and hyperkalaemia. EAHFE- renal dysfunction and hyperkalaemia
title_full Acute heart failure and adverse events associated with the presence of renal dysfunction and hyperkalaemia. EAHFE- renal dysfunction and hyperkalaemia
title_fullStr Acute heart failure and adverse events associated with the presence of renal dysfunction and hyperkalaemia. EAHFE- renal dysfunction and hyperkalaemia
title_full_unstemmed Acute heart failure and adverse events associated with the presence of renal dysfunction and hyperkalaemia. EAHFE- renal dysfunction and hyperkalaemia
title_sort Acute heart failure and adverse events associated with the presence of renal dysfunction and hyperkalaemia. EAHFE- renal dysfunction and hyperkalaemia
dc.creator.none.fl_str_mv Jacob, Javier
Llauger, Lluis
Herrero-Puente, Pablo
Martín-Sánchez, Francisco J.
Llorens, Pere
Roset, Alex
Gil, Víctor
Fuentes, Marta
Lucas-Imbernón, Francisco Javier
Miró, Òscar
ICA-SEMES Research Group
author Jacob, Javier
author_facet Jacob, Javier
Llauger, Lluis
Herrero-Puente, Pablo
Martín-Sánchez, Francisco J.
Llorens, Pere
Roset, Alex
Gil, Víctor
Fuentes, Marta
Lucas-Imbernón, Francisco Javier
Miró, Òscar
ICA-SEMES Research Group
author_role author
author2 Llauger, Lluis
Herrero-Puente, Pablo
Martín-Sánchez, Francisco J.
Llorens, Pere
Roset, Alex
Gil, Víctor
Fuentes, Marta
Lucas-Imbernón, Francisco Javier
Miró, Òscar
ICA-SEMES Research Group
author2_role author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Acute heart failure
Hyperkalaemia
Outcomes
Renal dysfunction
topic Acute heart failure
Hyperkalaemia
Outcomes
Renal dysfunction
description Objective: To study the outcomes of patients with acute heart failure (AHF) presenting renal dysfunction (RD) or hyperkalaemia (Hk) alone or in combination. Method: We analysed the data of the EAHFE registry, a multicentre, non interventionist cohort with prospective follow-up of patients with AHF. Four groups were defined based on the presence or not of RD or Hk alone or in combination. The primary endpoint was 30-day all-cause mortality. Results: A total of 11,935 of the 13,791 patients included in the EAHFE registry were analysed. Of these, 5088 (42.6%) did not have RD or Hk (NoRD-NoHk), 150 (1.3%) had no RD but had Hk (NoRD-Hk), 6012 (50.4%) had RD but not Hk (RD-NoHk) and 685 (5.7%) had both RD and Hk (RD-Hk). Thirty-day all-cause mortality was greatest in the RD-Hk group with an adjusted Hazard Ratio (HR) of 2.44 (confidence interval 95% [CI95%] 1.67-3.55; p < 0.001) and in the RD-NoHk group with an adjusted HR of 1.34 (CI95% 1.04-1.71; p = 0.022). There were no significant differences in in-hospital mortality and reconsultation at 30 days for HF. For the combined endpoint of 30-day all-cause mortality the adjusted HR was 1.33 (CI95% 1.04-1.70); (p = 0.021) for the RD-Hk group. Conclusions: The association of 30-day all-cause mortality with the presence of RD and Hk in patients presenting AHF at admission is greater than in those without this combination.
publishDate 2019
dc.date.none.fl_str_mv 2019
2020
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10230/43252
http://dx.doi.org/10.1016/j.ejim.2019.07.010
url http://hdl.handle.net/10230/43252
http://dx.doi.org/10.1016/j.ejim.2019.07.010
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv © Elsevier http://dx.doi.org/10.1016/j.ejim.2019.07.010
info:eu-repo/semantics/openAccess
rights_invalid_str_mv © Elsevier http://dx.doi.org/10.1016/j.ejim.2019.07.010
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositorio Digital de la UPF
instname:Universitat Pompeu Fabra
instname_str Universitat Pompeu Fabra
reponame_str Repositorio Digital de la UPF
collection Repositorio Digital de la UPF
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869409557920350208
score 15,812429

Similares en LA Referencia