Are obesity indices useful for detecting subclinical atheromatosis in a middle-aged population?
Objective: There is a close relationship between excess adiposity and cardiovascular disease. Although body mass index (BMI) is the most used approach to estimate excess weight, other anthropometric indices have been developed to measure total body and abdominal adiposity. Here, our objective was to...
| Autores: | , , , , , , , , , , , , , |
|---|---|
| Tipo de recurso: | artículo |
| Fecha de publicación: | 2020 |
| País: | España |
| Institución: | Universidad de Navarra |
| Repositorio: | Dadun. Depósito Académico Digital de la Universidad de Navarra |
| Idioma: | inglés |
| OAI Identifier: | oai:dadun.unav.edu:10171/65482 |
| Acceso en línea: | https://hdl.handle.net/10171/65482 |
| Access Level: | acceso abierto |
| Palabra clave: | Obesity indices Adipose tissue Excess body weight Subclinical atheromatosis |
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Are obesity indices useful for detecting subclinical atheromatosis in a middle-aged population?Sánchez, E. (Enric)|||/items/d3da2e56-a1c7-4333-a84d-f10649816831Sánchez, M. (Marta)|||/items/73dfca4f-617e-4ae3-9861-aefd7c01f36bBetriu, À. (Àngels)|||/items/015f6e6f-5c37-42b2-a508-f694affa8bf2Rius, F. (Ferran)|||/items/5889e57c-e592-41d3-95ac-1c050f0ee376Torres, G. (Gerard)|||/items/dffc75d9-d0ed-44c8-828b-800a5e71783cPurroy, F. (Francesc)|||/items/34cb6f23-302b-4c1f-afa2-617409ff9ffcPamplona, R. (Reinald)|||/items/e7975659-b299-4f5a-b607-6987147ef0cdOrtega, M. (Marta)|||/items/6a962c53-614f-4345-af9e-f676ccd2ba7eLópez-Cano, C. (Carolina)|||/items/2339e540-bc9f-4446-9afb-1b9e3ca16dccHernandez, M. (Marta)|||/items/969efd78-4f86-4c2a-8645-dee44a71fe7dBueno, M. (Marta)|||/items/ef8b61d6-e9c2-4e4b-be66-38ccd4910665Fernandez, E. (Elvira)|||/items/e8515a28-4a48-4f1b-a019-30877fb44ffbSalvador-Rodríguez, F.J. (Francisco Javier)|||/items/1175815b-412b-41a6-b91f-6dbfa349f9c8Lecube, A. (Albert)|||/items/124fad00-5deb-427d-8762-d6caa034f350Obesity indicesAdipose tissueExcess body weightSubclinical atheromatosisObjective: There is a close relationship between excess adiposity and cardiovascular disease. Although body mass index (BMI) is the most used approach to estimate excess weight, other anthropometric indices have been developed to measure total body and abdominal adiposity. Here, our objective was to assess the usefulness of these anthropometric indices to detect subclinical atheromatous disease. Methods: A cross-sectional study with 6,809 middle-aged subjects (mean age, 57 [53–63] years) with low to moderate cardiovascular risk from the ILERVAS project. Measures of total body fat (BMI, Clínica Universidad de Navarra – Body Adiposity Estimator [CUN-BAE], and Deurenberg’s formula) and central adiposity (waist and neck circumferences, conicity index, waist-to-height ratio, Bonora’s equation, the A body adiposity index, and body roundness index) were performed in all participants. Bilateral carotid and femoral ultrasound vascular studies allowed the identification of subjects with plaque. Results: All measured indices were significantly higher in males with subclinical carotid or femoral plaques (p ≤ 0.021 for all). Also, a positive and significant correlation between all indices and the number of affected territories was found (p ≤ 0.013 for all). From the ROC analysis, all measurements identified patients with asymptomatic atheromatosis but none of them helped make clinical decisions. Regarding females, the results were less conclusive. Conclusion: Obesity indices are related to subclinical atheromatosis, especially in men, in a large cohort of middle-aged subjects. However, the indices could not detect the presence of arterial plaque, so, when used in isolation, are unlikely to be decisive.KargerDadun. Depósito Académico Digital Universidad de Navarra20232023-02-1420202020-01-0120202020-01-01journal articlehttp://purl.org/coar/resource_type/c_6501info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10171/65482reponame:Dadun. Depósito Académico Digital de la Universidad de Navarrainstname:Universidad de NavarraInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:dadun.unav.edu:10171/654822026-06-21T12:47:57Z |
| dc.title.none.fl_str_mv |
Are obesity indices useful for detecting subclinical atheromatosis in a middle-aged population? |
| title |
Are obesity indices useful for detecting subclinical atheromatosis in a middle-aged population? |
| spellingShingle |
Are obesity indices useful for detecting subclinical atheromatosis in a middle-aged population? Sánchez, E. (Enric)|||/items/d3da2e56-a1c7-4333-a84d-f10649816831 Obesity indices Adipose tissue Excess body weight Subclinical atheromatosis |
| title_short |
Are obesity indices useful for detecting subclinical atheromatosis in a middle-aged population? |
| title_full |
Are obesity indices useful for detecting subclinical atheromatosis in a middle-aged population? |
| title_fullStr |
Are obesity indices useful for detecting subclinical atheromatosis in a middle-aged population? |
| title_full_unstemmed |
Are obesity indices useful for detecting subclinical atheromatosis in a middle-aged population? |
| title_sort |
Are obesity indices useful for detecting subclinical atheromatosis in a middle-aged population? |
| dc.creator.none.fl_str_mv |
Sánchez, E. (Enric)|||/items/d3da2e56-a1c7-4333-a84d-f10649816831 Sánchez, M. (Marta)|||/items/73dfca4f-617e-4ae3-9861-aefd7c01f36b Betriu, À. (Àngels)|||/items/015f6e6f-5c37-42b2-a508-f694affa8bf2 Rius, F. (Ferran)|||/items/5889e57c-e592-41d3-95ac-1c050f0ee376 Torres, G. (Gerard)|||/items/dffc75d9-d0ed-44c8-828b-800a5e71783c Purroy, F. (Francesc)|||/items/34cb6f23-302b-4c1f-afa2-617409ff9ffc Pamplona, R. (Reinald)|||/items/e7975659-b299-4f5a-b607-6987147ef0cd Ortega, M. (Marta)|||/items/6a962c53-614f-4345-af9e-f676ccd2ba7e López-Cano, C. (Carolina)|||/items/2339e540-bc9f-4446-9afb-1b9e3ca16dcc Hernandez, M. (Marta)|||/items/969efd78-4f86-4c2a-8645-dee44a71fe7d Bueno, M. (Marta)|||/items/ef8b61d6-e9c2-4e4b-be66-38ccd4910665 Fernandez, E. (Elvira)|||/items/e8515a28-4a48-4f1b-a019-30877fb44ffb Salvador-Rodríguez, F.J. (Francisco Javier)|||/items/1175815b-412b-41a6-b91f-6dbfa349f9c8 Lecube, A. (Albert)|||/items/124fad00-5deb-427d-8762-d6caa034f350 |
| author |
Sánchez, E. (Enric)|||/items/d3da2e56-a1c7-4333-a84d-f10649816831 |
| author_facet |
Sánchez, E. (Enric)|||/items/d3da2e56-a1c7-4333-a84d-f10649816831 Sánchez, M. (Marta)|||/items/73dfca4f-617e-4ae3-9861-aefd7c01f36b Betriu, À. (Àngels)|||/items/015f6e6f-5c37-42b2-a508-f694affa8bf2 Rius, F. (Ferran)|||/items/5889e57c-e592-41d3-95ac-1c050f0ee376 Torres, G. (Gerard)|||/items/dffc75d9-d0ed-44c8-828b-800a5e71783c Purroy, F. (Francesc)|||/items/34cb6f23-302b-4c1f-afa2-617409ff9ffc Pamplona, R. (Reinald)|||/items/e7975659-b299-4f5a-b607-6987147ef0cd Ortega, M. (Marta)|||/items/6a962c53-614f-4345-af9e-f676ccd2ba7e López-Cano, C. (Carolina)|||/items/2339e540-bc9f-4446-9afb-1b9e3ca16dcc Hernandez, M. (Marta)|||/items/969efd78-4f86-4c2a-8645-dee44a71fe7d Bueno, M. (Marta)|||/items/ef8b61d6-e9c2-4e4b-be66-38ccd4910665 Fernandez, E. (Elvira)|||/items/e8515a28-4a48-4f1b-a019-30877fb44ffb Salvador-Rodríguez, F.J. (Francisco Javier)|||/items/1175815b-412b-41a6-b91f-6dbfa349f9c8 Lecube, A. (Albert)|||/items/124fad00-5deb-427d-8762-d6caa034f350 |
| author_role |
author |
| author2 |
Sánchez, M. (Marta)|||/items/73dfca4f-617e-4ae3-9861-aefd7c01f36b Betriu, À. (Àngels)|||/items/015f6e6f-5c37-42b2-a508-f694affa8bf2 Rius, F. (Ferran)|||/items/5889e57c-e592-41d3-95ac-1c050f0ee376 Torres, G. (Gerard)|||/items/dffc75d9-d0ed-44c8-828b-800a5e71783c Purroy, F. (Francesc)|||/items/34cb6f23-302b-4c1f-afa2-617409ff9ffc Pamplona, R. (Reinald)|||/items/e7975659-b299-4f5a-b607-6987147ef0cd Ortega, M. (Marta)|||/items/6a962c53-614f-4345-af9e-f676ccd2ba7e López-Cano, C. (Carolina)|||/items/2339e540-bc9f-4446-9afb-1b9e3ca16dcc Hernandez, M. (Marta)|||/items/969efd78-4f86-4c2a-8645-dee44a71fe7d Bueno, M. (Marta)|||/items/ef8b61d6-e9c2-4e4b-be66-38ccd4910665 Fernandez, E. (Elvira)|||/items/e8515a28-4a48-4f1b-a019-30877fb44ffb Salvador-Rodríguez, F.J. (Francisco Javier)|||/items/1175815b-412b-41a6-b91f-6dbfa349f9c8 Lecube, A. (Albert)|||/items/124fad00-5deb-427d-8762-d6caa034f350 |
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author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Dadun. Depósito Académico Digital Universidad de Navarra |
| dc.subject.none.fl_str_mv |
Obesity indices Adipose tissue Excess body weight Subclinical atheromatosis |
| topic |
Obesity indices Adipose tissue Excess body weight Subclinical atheromatosis |
| description |
Objective: There is a close relationship between excess adiposity and cardiovascular disease. Although body mass index (BMI) is the most used approach to estimate excess weight, other anthropometric indices have been developed to measure total body and abdominal adiposity. Here, our objective was to assess the usefulness of these anthropometric indices to detect subclinical atheromatous disease. Methods: A cross-sectional study with 6,809 middle-aged subjects (mean age, 57 [53–63] years) with low to moderate cardiovascular risk from the ILERVAS project. Measures of total body fat (BMI, Clínica Universidad de Navarra – Body Adiposity Estimator [CUN-BAE], and Deurenberg’s formula) and central adiposity (waist and neck circumferences, conicity index, waist-to-height ratio, Bonora’s equation, the A body adiposity index, and body roundness index) were performed in all participants. Bilateral carotid and femoral ultrasound vascular studies allowed the identification of subjects with plaque. Results: All measured indices were significantly higher in males with subclinical carotid or femoral plaques (p ≤ 0.021 for all). Also, a positive and significant correlation between all indices and the number of affected territories was found (p ≤ 0.013 for all). From the ROC analysis, all measurements identified patients with asymptomatic atheromatosis but none of them helped make clinical decisions. Regarding females, the results were less conclusive. Conclusion: Obesity indices are related to subclinical atheromatosis, especially in men, in a large cohort of middle-aged subjects. However, the indices could not detect the presence of arterial plaque, so, when used in isolation, are unlikely to be decisive. |
| publishDate |
2020 |
| dc.date.none.fl_str_mv |
2020 2020-01-01 2020 2020-01-01 2023 2023-02-14 |
| dc.type.none.fl_str_mv |
journal article http://purl.org/coar/resource_type/c_6501 |
| dc.type.openaire.fl_str_mv |
info:eu-repo/semantics/article |
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article |
| dc.identifier.none.fl_str_mv |
https://hdl.handle.net/10171/65482 |
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https://hdl.handle.net/10171/65482 |
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Inglés eng |
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Inglés |
| language |
eng |
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open access http://purl.org/coar/access_right/c_abf2 |
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info:eu-repo/semantics/openAccess |
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open access http://purl.org/coar/access_right/c_abf2 |
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openAccess |
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application/pdf |
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Karger |
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Karger |
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reponame:Dadun. Depósito Académico Digital de la Universidad de Navarra instname:Universidad de Navarra |
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Universidad de Navarra |
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Dadun. Depósito Académico Digital de la Universidad de Navarra |
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