Características clínicas de los pacientes hospitalizados con COVID-19 en España: Resultados del Registro SEMI-COVID-19

Background: Spain has been one of the countries most affected by the COVID-19 pandemic. Objective: To create a registry of patients with COVID-19 hospitalized in Spain, in order to improve our knowledge of the clinical, diagnostic, therapeutic, and prognostic aspects of this disease. Methods: A mult...

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Detalhes bibliográficos
Autores: Casas-Rojo, J. M., Antón-Santos, J. M., Millán-Núñez-Cortés, J., Lumbreras-Bermejo, C., Ramos-Rincón, J. M., Roy-Vallejo, E., Artero-Mora, A., Arnalich Fernández, Francisco, García-Bruñén, J. M., Vargas Núñez, Juan Antonio, Freire-Castro, S. J., Manzano-Espinosa, L., Perales-Fraile, I., Crestelo-Viéitez, A., Puchades-Gimeno, F., Rodilla-Sala, E., Solís-Marquínez, M. N., Bonet-Tur, D., Fidalgo-Moreno, M. P., Fonseca-Aizpuru, E. M., Carrasco-Sánchez, F. J., Rabadán-Pejenaute, E., Rubio-Rivas, M., Torres-Peña, J. D., Gómez-Huelgas, R., Grupo SEMI-COVID-19 Network
Formato: artículo
Fecha de publicación:2020
País:España
Recursos:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/695448
Acesso em linha:http://hdl.handle.net/10486/695448
https://dx.doi.org/10.1016/j.rce.2020.07.003
Access Level:acceso abierto
Palavra-chave:2019-nCoV
Coronavirus
COVID-19
SARS-CoV-2
Spain
Medicina
Descrição
Resumo:Background: Spain has been one of the countries most affected by the COVID-19 pandemic. Objective: To create a registry of patients with COVID-19 hospitalized in Spain, in order to improve our knowledge of the clinical, diagnostic, therapeutic, and prognostic aspects of this disease. Methods: A multicentre retrospective cohort study, including consecutive patients hospitalized with confirmed COVID-19 throughout Spain. Epidemiological and clinical data, additional tests at admission and at seven days, treatments administered, and progress at 30 days of hospitalization were collected from electronic medical records. Results: Up to June 30th 2020, 15,111 patients from 150 hospitals were included. Their median age was 69.4 years (range: 18-102 years) and 57.2% were male. Prevalences of hypertension, dyslipidemia, and diabetes mellitus were 50.9%, 39.7%, and 19.4%, respectively. The most frequent symptoms were fever (84.2%) and cough (73.5%). High values of ferritin (73.5%), lactate dehydrogenase (73.9%), and D-dimer (63.8%), as well as lymphopenia (52.8%), were frequent. The most used antiviral drugs were hydroxychloroquine (85.6%) and lopinavir/ritonavir (61.4%); 33.1% developed respiratory distress. Overall mortality rate was 21.0%, with a marked increase with age (50-59 years: 4.7%, 60-69 years: 10.5%, 70-79 years: 26.9%, ≥ 80 years: 46.0%). Conclusions: The SEMI-COVID-19 Network provides data on the clinical characteristics of patients with COVID-19 hospitalized in Spain. Patients with COVID-19 hospitalized in Spain are mostly severe cases, as one in three patients developed respiratory distress and one in five patients died. These findings confirm a close relationship between advanced age and mortality.

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