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The ENIGMA group on Generalized Anxiety Disorder (ENIGMA-Anxiety/GAD) is part of a broader effort to investigate anxiety disorders using imaging and genetic data across multiple sites worldwide. The group is actively conducting a mega-analysis of a large number of brain structural scans. In this pro...

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Autores: Zugman, André|||0000-0002-6126-7759, Harrewijn, Anita|||0000-0001-9938-4048, Cardinale, Elise M., Zwiebel, Hannah L., Freitag, Gabrielle F., Werwath, Katy E., Bas-Hoogendam, Janna Marie|||0000-0001-8982-1670, Groenewold, Nynke A.|||0000-0002-0865-8427, Aghajani, Moji|||0000-0003-2040-4881, Hilbert, Kevin|||0000-0002-7986-4113, Cardoner, Narcís|||0000-0001-9633-0888, Porta-Casteràs, Daniel|||0000-0002-3921-3607, Gosnell, Savannah, Salas, Ramiro|||0000-0002-1105-566X, Blair, Karina S., Blair, James R., Hammoud, Mira Z., Milad, Mohammed, Burkhouse, Katie, Phan, K. Luan, Schroeder, Heidi K., Strawn, Jeffrey R., Beesdo-Baum, Katja, Thomopoulos, Sophia I.|||0000-0002-0046-4070, Grabe, Hans J.|||0000-0003-3684-4208, Van der Auwera, Sandra, Wittfeld, Katharina|||0000-0003-4383-5043, Nielsen, Jared A.|||0000-0002-2717-193X, Buckner, Randy|||0000-0001-6422-8037, Smoller, Jordan W.|||0000-0002-0381-6334, Mwangi, Benson|||0000-0002-1717-4395, Soares, Jair C.|||0000-0002-5466-5628, Wu, Mon-Ju|||0000-0002-0540-8027, Zunta-Soares, Giovana B., Jackowski, Andrea P.|||0000-0001-8842-5406, Pan, Pedro M., Salum, Giovanni A., Assaf, Michal|||0000-0001-5307-1986, Diefenbach, Gretchen J., Brambilla, Paolo|||0000-0002-4021-8456, Maggioni, Eleonora, Hofmann, David|||0000-0003-3494-634X, Straube, Thomas, Andreescu, Carmen|||0000-0003-3767-5127, Berta, Rachel, Tamburo, Erica, Price, Rebecca, Manfro, Gisele G.|||0000-0002-0109-7591, Critchley, Hugo D.|||0000-0002-2445-9284, Makovac, Elena|||0000-0002-7018-1906, Mancini, Matteo, Meeten, Frances, Ottaviani, Cristina|||0000-0002-5240-4387, Agosta, Federica, Canu, Elisa, Cividini, Camilla, Filippi, Massimo|||0000-0002-5485-0479, Kostić, Milutin, Munjiza, Ana, Filippi, Courtney A., Leibenluft, Ellen, Alberton, Bianca A. V.|||0000-0001-7680-7300, Balderston, Nicholas L.|||0000-0002-8565-1544, Ernst, Monique, Grillon, Christian, Mujica-Parodi, Lilianne R.|||0000-0002-3752-5519, van Nieuwenhuizen, Helena, Fonzo, Gregory A.|||0000-0002-0213-1034, Paulus, Martin P.|||0000-0002-0825-3606, Stein, Murray B.|||0000-0001-9564-2871, Gur, Raquel E., Gur, Ruben C., Kaczkurkin, Antonia N.|||0000-0002-0943-3094, Larsen, Bart, Satterthwaite, Theodore D.|||0000-0001-7072-9399, Harper, Jennifer, Myers, Michael, Perino, Michael T., Yu, Qiongru, Sylvester, Chad M., Veltman, Dick J., Lueken, Ulrike|||0000-0003-1564-4012, Van der Wee, Nic J. A., Stein, Dan J.|||0000-0001-7218-7810, Jahanshad, Neda|||0000-0003-4401-8950, Thompson, Paul M.|||0000-0002-4720-8867, Pine, Daniel S., Winkler, Anderson M.|||0000-0002-4169-9781
Tipo de recurso: artículo
Fecha de publicación:2020
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:252713
Acceso en línea:https://ddd.uab.cat/record/252713
https://dx.doi.org/urn:doi:10.1002/hbm.25096
Access Level:acceso abierto
Palabra clave:Data sharing
Generalized anxiety disorder
Mega-analyses
Meta-analyses
Neuroimaging
Descripción
Sumario:The ENIGMA group on Generalized Anxiety Disorder (ENIGMA-Anxiety/GAD) is part of a broader effort to investigate anxiety disorders using imaging and genetic data across multiple sites worldwide. The group is actively conducting a mega-analysis of a large number of brain structural scans. In this process, the group was confronted with many methodological challenges related to study planning and implementation, between-country transfer of subject-level data, quality control of a considerable amount of imaging data, and choices related to statistical methods and efficient use of resources. This report summarizes the background information and rationale for the various methodological decisions, as well as the approach taken to implement them. The goal is to document the approach and help guide other research groups working with large brain imaging data sets as they develop their own analytic pipelines for mega-analyses. This report summarizes the background information and rationale for the various methodological decisions made by the ENIGMA-GAD group. The aim of this work is to help guide other research groups working with large brain imaging data sets.

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