Rh-catalysed single-carbon insertion to 1,3-dienes

Herein, we report the first catalytic single-carbon insertion to 1,3-dienes with Rh(II)-carbynoids. The skeletal editing process is based on the catalytic generation of a Rh-carbynoid that promotes the insertion of a cationic monovalent carbon unit (:+C–R) into the C(sp2)–C(sp2) bond of the 1,3-dien...

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Detalles Bibliográficos
Autores: Sarró, Pau, Díaz, Norman, Esteve Guasch, Josep, Teo, Wei Jie, Suero, Marcos G.
Tipo de recurso: artículo
Fecha de publicación:2025
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2072/484479
Acceso en línea:http://hdl.handle.net/2072/484479
https://doi.org/10.1039/D5SC03161C
Access Level:acceso abierto
Palabra clave:Química
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Descripción
Sumario:Herein, we report the first catalytic single-carbon insertion to 1,3-dienes with Rh(II)-carbynoids. The skeletal editing process is based on the catalytic generation of a Rh-carbynoid that promotes the insertion of a cationic monovalent carbon unit (:+C–R) into the C(sp2)–C(sp2) bond of the 1,3-diene, leading to a pentadienyl cation. Regioselective attack on the latter species leads to the formation of multi-substituted 1,3-dienes or 1,4-dienes with a broad range of carbon and heteroatomic nucleophiles.