Impact of hemoperfusion with polymyxin B added to hemofiltration in patients with endotoxic shock

Septic shock is a leading cause of death in critical patients. In patients with gram-negative septic shock, hemoperfusion with polymyxin B aims to remove endotoxins from plasma. We analyzed the clinical and biological response to hemoperfusion in patients with septic shock and acute kidney injury. T...

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Detalhes bibliográficos
Autores: Navas Pérez, Ana Maria|||0000-0002-2860-4864, Ferrer, Ricard|||0000-0002-4859-4747, Martínez, Maria Luisa, Gomà, Gemma|||0000-0002-1890-4855, Gili, Gisela, Masip, Jordi, Suárez, David, Artigas Raventós, Antoni|||0000-0002-8029-1017
Tipo de documento: artigo
Data de publicação:2018
País:España
Recursos:Universitat Autònoma de Barcelona
Repositório:Dipòsit Digital de Documents de la UAB
Idioma:inglês
OAI Identifier:oai:ddd.uab.cat:253755
Acesso em linha:https://ddd.uab.cat/record/253755
https://dx.doi.org/urn:doi:10.1186/s13613-018-0465-8
Access Level:Acceso aberto
Palavra-chave:Endotoxic shock
Hemoperfusion
Polymyxin B
Acute kidney injury
Hemofiltration
Descrição
Resumo:Septic shock is a leading cause of death in critical patients. In patients with gram-negative septic shock, hemoperfusion with polymyxin B aims to remove endotoxins from plasma. We analyzed the clinical and biological response to hemoperfusion in patients with septic shock and acute kidney injury. This prospective case-control study in the medical-surgical intensive care unit of a university hospital included consecutive adults patients with septic shock and suspected gram-negative bacteria infection with elevated plasma endotoxin activity (EAA