Correlation of atrophy measures on MRI with neuropsychological sequelae in child and adolescents with traumatic brain injury

To examine the relationship between neuropsychological sequelae and atrophy parameters from magnetic resonance imaging (MRI) following paediatric moderate-to-severe traumatic brain injury (TBI), 19 head injured children and adolescents were studied at least 6 years after injury. Three-dimensional MR...

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Detalles Bibliográficos
Autores: Verger Maestre, Katia, Junqué i Plaja, Carme, 1955-, Levin, Harvey S., Jurado, Ma. Ángeles (María Ángeles), Pérez Gómez, Mercedes, Bartrés Faz, David, Barrios Cerrejón, M. Teresa, Álvarez Amador, Alfredo, Bartumeus Ferré, Frederic, Mercader Sobrequés, José Ma.
Tipo de recurso: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2001
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/226986
Acceso en línea:https://hdl.handle.net/2445/226986
Access Level:acceso abierto
Palabra clave:Cervell
Pediatria
Imatges per ressonància magnètica
Brain
Pediatrics
Magnetic resonance imaging
Descripción
Sumario:To examine the relationship between neuropsychological sequelae and atrophy parameters from magnetic resonance imaging (MRI) following paediatric moderate-to-severe traumatic brain injury (TBI), 19 head injured children and adolescents were studied at least 6 years after injury. Three-dimensional MRI scans were obtained. A semi-automatic computerized method was used to estimate ventricular volumes and the corpus callosum area. Tests of intellectual, memory, visuospatial, frontal lobe, and motor speed functioning were administered to all patients and to 19 matched normal control subjects. Patients' performance significantly differed from controls in general intellectual function, visual memory, visuospatial and frontal lobe tests. The corpus callosum area correlated strongly with several measures involving processing speed and visuospatial function. Ventricular enlargement was less related to neuropsychological outcome. In conclusion, quantitative measurement of the corpus callosum on MRI reflects neuropsychological outcome better than ventricular dilation in paediatric patients.

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