Bimetallic Pd/CuO nanoparticles obtained by laser re-irradiation in liquids for antibacterial applications

Antimicrobial resistance (AMR) is considered a major global health problem of the 21st century. Noble metal nanoparticles (NPs) have attracted increasing attention as a promising tool to fight against resistant infections. In this research, we explore bimetallic NPs, as they can give rise to further...

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Autores: Vilas, Ana María, Fernández Arias, M., Boutinguiza Larosi, Mohamed, Rodríguez Rius, Daniel|||0000-0001-6286-5200, Solla, Eugenio, Vilella i Crosas, Tània|||0000-0002-9135-5637, del Val García, Jesús, Riveiro Rodríguez, Antonio, Gil Mur, Francisco Javier|||0000-0002-6824-1412, Pou Saracho, Juan María
Formato: artículo
Fecha de publicación:2025
País:España
Recursos:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/433498
Acesso em linha:https://hdl.handle.net/2117/433498
https://dx.doi.org/10.1016/j.apsadv.2025.100735
Access Level:acceso abierto
Palavra-chave:Palladium-copper nanoparticles
Laser ablation
Re-irradiation
Bactericidal activity
Cytocompatibility
Àrees temàtiques de la UPC::Enginyeria dels materials
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spelling Bimetallic Pd/CuO nanoparticles obtained by laser re-irradiation in liquids for antibacterial applicationsVilas, Ana MaríaFernández Arias, M.Boutinguiza Larosi, MohamedRodríguez Rius, Daniel|||0000-0001-6286-5200Solla, EugenioVilella i Crosas, Tània|||0000-0002-9135-5637del Val García, JesúsRiveiro Rodríguez, AntonioGil Mur, Francisco Javier|||0000-0002-6824-1412Pou Saracho, Juan MaríaPalladium-copper nanoparticlesLaser ablationRe-irradiationBactericidal activityCytocompatibilityÀrees temàtiques de la UPC::Enginyeria dels materialsAntimicrobial resistance (AMR) is considered a major global health problem of the 21st century. Noble metal nanoparticles (NPs) have attracted increasing attention as a promising tool to fight against resistant infections. In this research, we explore bimetallic NPs, as they can give rise to further and improved physicochemical and biological properties. In this work, monometallic Cu/CuO and Pd NPs were synthesized by laser ablation. Af- terwards, these NPs were mixed and the resulting colloidal solution was multiply re-irradiated with the aim of producing Pd/CuO bimetallic NPs. All the NPs presented rounded shape and crystalline microstructure. Although the re-irradiated NPs contained both precursor materials, all characterization techniques agreed on the occur- rence of an intermetallic alloy of both materials, Cu3Pd, that is concluded to be formed as a consequence of the interaction between the laser beam and the mixture of monometallic NPs. With the objective of studying anti- microbial activity against Staphylococcus aureus, the CuO NPs, Pd NPs and Pd/CuO NPs were immobilized on the surface of titanium discs. Ion release was tracked during the first 24 h and cytotoxicity of the immobilized NPs was as well tested with HFF-1 human fibroblast cell line. Bimetallic Pd/CuO NPs showed a significant inhibitory effect on S. aureus and no toxic impact on fibroblasts.Elsevier BV20252025-06-0120252025-07-04journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/2117/433498https://dx.doi.org/10.1016/j.apsadv.2025.100735reponame:UPCommons. Portal del coneixement obert de la UPCinstname:Universitat Politècnica de Catalunya (UPC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccessoai:upcommons.upc.edu:2117/4334982026-05-27T15:37:01Z
dc.title.none.fl_str_mv Bimetallic Pd/CuO nanoparticles obtained by laser re-irradiation in liquids for antibacterial applications
title Bimetallic Pd/CuO nanoparticles obtained by laser re-irradiation in liquids for antibacterial applications
spellingShingle Bimetallic Pd/CuO nanoparticles obtained by laser re-irradiation in liquids for antibacterial applications
Vilas, Ana María
Palladium-copper nanoparticles
Laser ablation
Re-irradiation
Bactericidal activity
Cytocompatibility
Àrees temàtiques de la UPC::Enginyeria dels materials
title_short Bimetallic Pd/CuO nanoparticles obtained by laser re-irradiation in liquids for antibacterial applications
title_full Bimetallic Pd/CuO nanoparticles obtained by laser re-irradiation in liquids for antibacterial applications
title_fullStr Bimetallic Pd/CuO nanoparticles obtained by laser re-irradiation in liquids for antibacterial applications
title_full_unstemmed Bimetallic Pd/CuO nanoparticles obtained by laser re-irradiation in liquids for antibacterial applications
title_sort Bimetallic Pd/CuO nanoparticles obtained by laser re-irradiation in liquids for antibacterial applications
dc.creator.none.fl_str_mv Vilas, Ana María
Fernández Arias, M.
Boutinguiza Larosi, Mohamed
Rodríguez Rius, Daniel|||0000-0001-6286-5200
Solla, Eugenio
Vilella i Crosas, Tània|||0000-0002-9135-5637
del Val García, Jesús
Riveiro Rodríguez, Antonio
Gil Mur, Francisco Javier|||0000-0002-6824-1412
Pou Saracho, Juan María
author Vilas, Ana María
author_facet Vilas, Ana María
Fernández Arias, M.
Boutinguiza Larosi, Mohamed
Rodríguez Rius, Daniel|||0000-0001-6286-5200
Solla, Eugenio
Vilella i Crosas, Tània|||0000-0002-9135-5637
del Val García, Jesús
Riveiro Rodríguez, Antonio
Gil Mur, Francisco Javier|||0000-0002-6824-1412
Pou Saracho, Juan María
author_role author
author2 Fernández Arias, M.
Boutinguiza Larosi, Mohamed
Rodríguez Rius, Daniel|||0000-0001-6286-5200
Solla, Eugenio
Vilella i Crosas, Tània|||0000-0002-9135-5637
del Val García, Jesús
Riveiro Rodríguez, Antonio
Gil Mur, Francisco Javier|||0000-0002-6824-1412
Pou Saracho, Juan María
author2_role author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Palladium-copper nanoparticles
Laser ablation
Re-irradiation
Bactericidal activity
Cytocompatibility
Àrees temàtiques de la UPC::Enginyeria dels materials
topic Palladium-copper nanoparticles
Laser ablation
Re-irradiation
Bactericidal activity
Cytocompatibility
Àrees temàtiques de la UPC::Enginyeria dels materials
description Antimicrobial resistance (AMR) is considered a major global health problem of the 21st century. Noble metal nanoparticles (NPs) have attracted increasing attention as a promising tool to fight against resistant infections. In this research, we explore bimetallic NPs, as they can give rise to further and improved physicochemical and biological properties. In this work, monometallic Cu/CuO and Pd NPs were synthesized by laser ablation. Af- terwards, these NPs were mixed and the resulting colloidal solution was multiply re-irradiated with the aim of producing Pd/CuO bimetallic NPs. All the NPs presented rounded shape and crystalline microstructure. Although the re-irradiated NPs contained both precursor materials, all characterization techniques agreed on the occur- rence of an intermetallic alloy of both materials, Cu3Pd, that is concluded to be formed as a consequence of the interaction between the laser beam and the mixture of monometallic NPs. With the objective of studying anti- microbial activity against Staphylococcus aureus, the CuO NPs, Pd NPs and Pd/CuO NPs were immobilized on the surface of titanium discs. Ion release was tracked during the first 24 h and cytotoxicity of the immobilized NPs was as well tested with HFF-1 human fibroblast cell line. Bimetallic Pd/CuO NPs showed a significant inhibitory effect on S. aureus and no toxic impact on fibroblasts.
publishDate 2025
dc.date.none.fl_str_mv 2025
2025-06-01
2025
2025-07-04
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/2117/433498
https://dx.doi.org/10.1016/j.apsadv.2025.100735
url https://hdl.handle.net/2117/433498
https://dx.doi.org/10.1016/j.apsadv.2025.100735
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution-NonCommercial-NoDerivatives 4.0 International
http://creativecommons.org/licenses/by-nc-nd/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier BV
publisher.none.fl_str_mv Elsevier BV
dc.source.none.fl_str_mv reponame:UPCommons. Portal del coneixement obert de la UPC
instname:Universitat Politècnica de Catalunya (UPC)
instname_str Universitat Politècnica de Catalunya (UPC)
reponame_str UPCommons. Portal del coneixement obert de la UPC
collection UPCommons. Portal del coneixement obert de la UPC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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