Left Atrial Appendage Closure with a New Occluder Device

The LAmbre TM device is a novel system designed for left atrial appendage closure (LAAC). First registries showed a high rate of device implantation success. However, few mid-term results are available. We present our 1- and 12-month follow-up results for this device. This prospective, single-center...

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Detalles Bibliográficos
Autores: Llagostera-Martín, Marc|||0000-0002-6211-7453, Cubero-Gallego, Hector|||0000-0001-9740-827X, Mas-Stachurska, Aleksandra|||0000-0003-4947-4111, Salvatella, Neus, Sánchez-Carpintero, Andrea, Tizón-Marcos, Helena|||0000-0001-7942-9413, García-Guimaraes, Marcos|||0000-0001-8509-6184, Calvo-Fernández, Alicia|||0000-0001-6504-3528, Molina, Luis, Vaquerizo, Beatriz|||0000-0002-1428-3596
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universitat Autònoma de Barcelona
Repositorio:Dipòsit Digital de Documents de la UAB
Idioma:inglés
OAI Identifier:oai:ddd.uab.cat:255492
Acceso en línea:https://ddd.uab.cat/record/255492
https://dx.doi.org/urn:doi:10.3390/jcm10071421
Access Level:acceso abierto
Palabra clave:Left atrial appendage closure
Atrial fibrillation
Stroke
LAmbre
Descripción
Sumario:The LAmbre TM device is a novel system designed for left atrial appendage closure (LAAC). First registries showed a high rate of device implantation success. However, few mid-term results are available. We present our 1- and 12-month follow-up results for this device. This prospective, single-center registry included consecutive patients with nonvalvular atrial fibrillation who underwent LAAC with the LAmbre TM device. Transesophageal echocardiography (TEE) was performed at 1-month follow-up. In total, 55 patients were included. The population was elderly (75 ± 9.4 years), with a high proportion of comorbidities. The mean CHADS-VASc and HAS-BLED scores were 4.6 ± 1.6 and 3.9 ± 1.0, respectively. Previous history of a major bleeding event was present in 37 patients (67.3%). Procedural success was achieved in 54 patients (98.2%). Device success was achieved in 100% of patients in whom device implantation was attempted (54 patients). Major in-hospital device-related complications included mortality of one patient (1.8%) and pericardial tamponade in two patients (3.6%); the incidence of stroke was 0%. No thrombus or significant leaks (≥5 mm) were observed on 1-month TEE. At 12 months, adverse events were overall death (1.8%), transient ischemic attack/ischemic stroke (1.8%), and major bleeding events (Bleeding Academic Research Consortium (BARC) 3a and 3c; 11%). In this high-risk population, the LAmbre TM device seems to be a safe and effective option for LAAC with a remarkable mid-term performance.