Two Host Clades, Two Bacterial Arsenals: Evolution through Gene Losses in Facultative Endosymbionts

Bacterial endosymbiosis is an important evolutionary process in insects, which can harbor both obligate and facultative symbionts. The evolution of these symbionts is driven by evolutionary convergence, and they exhibit among the tiniest genomes in prokaryotes. The large host spectrum of facultative...

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Autores: Rollat-Farnier PA, Santos-Garcia D, Rao Q, Sagot MF, Silva FJ, Henri H, Zchori-Fein E, Latorre A, Moya A, Barbe V, Liu SS, Wang XW, Vavre F, Mouton L
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2015
País:España
Institución:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
Repositorio:r-FISABIO. Repositorio Institucional de Producción Científica
OAI Identifier:oai:fisabio.fundanetsuite.com:p4668
Acceso en línea:https://fisabio.portalinvestigacion.com/publicaciones/4668
Access Level:acceso abierto
Palabra clave:comparative genomics
Hamiltonella defensa
aphids
Bemisia tabaci
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spelling Two Host Clades, Two Bacterial Arsenals: Evolution through Gene Losses in Facultative EndosymbiontsRollat-Farnier PASantos-Garcia DRao QSagot MFSilva FJHenri HZchori-Fein ELatorre AMoya ABarbe VLiu SSWang XWVavre FMouton Lcomparative genomicsHamiltonella defensaaphidsBemisia tabaciBacterial endosymbiosis is an important evolutionary process in insects, which can harbor both obligate and facultative symbionts. The evolution of these symbionts is driven by evolutionary convergence, and they exhibit among the tiniest genomes in prokaryotes. The large host spectrum of facultative symbionts and the high diversity of strategies they use to infect new hosts probably impact the evolution of their genome and explain why they undergo less severe genomic erosion than obligate symbionts. Candidatus Hamiltonella defensa is suitable for the investigation of the genomic evolution of facultative symbionts because the bacteria are engaged in specific relationships in two clades of insects. In aphids, H. defensa is found in several species with an intermediate prevalence and confers protection against parasitoids. In whiteflies, H. defensa is almost fixed in some species of Bemisia tabaci, which suggests an important role of and a transition toward obligate symbiosis. In this study, comparisons of the genome of H. defensa present in two B. tabaci species ( Middle East Asia Minor 1 and Mediterranean) and in the aphid Acyrthosiphon pisum revealed that they belong to two distinct clades and underwent specific gene losses. In aphids, it contains highly virulent factors that could allow protection and horizontal transfers. In whiteflies, the genome lost these factors and seems to have a limited ability to acquire genes. However it contains genes that could be involved in the production of essential nutrients, which is consistent with a primordial role for this symbiont. In conclusion, although both lineages of H. defensa have mutualistic interactions with their hosts, their genomes follow distinct evolutionary trajectories that reflect their phenotype and could have important consequences on their evolvability.OXFORD UNIV PRESS2015info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://fisabio.portalinvestigacion.com/publicaciones/4668Genome Biology and EvolutionISSN: 17596653reponame:r-FISABIO. Repositorio Institucional de Producción Científicainstname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)Inglésinfo:eu-repo/semantics/openAccessoai:fisabio.fundanetsuite.com:p46682026-06-11T12:45:17Z
dc.title.none.fl_str_mv Two Host Clades, Two Bacterial Arsenals: Evolution through Gene Losses in Facultative Endosymbionts
title Two Host Clades, Two Bacterial Arsenals: Evolution through Gene Losses in Facultative Endosymbionts
spellingShingle Two Host Clades, Two Bacterial Arsenals: Evolution through Gene Losses in Facultative Endosymbionts
Rollat-Farnier PA
comparative genomics
Hamiltonella defensa
aphids
Bemisia tabaci
title_short Two Host Clades, Two Bacterial Arsenals: Evolution through Gene Losses in Facultative Endosymbionts
title_full Two Host Clades, Two Bacterial Arsenals: Evolution through Gene Losses in Facultative Endosymbionts
title_fullStr Two Host Clades, Two Bacterial Arsenals: Evolution through Gene Losses in Facultative Endosymbionts
title_full_unstemmed Two Host Clades, Two Bacterial Arsenals: Evolution through Gene Losses in Facultative Endosymbionts
title_sort Two Host Clades, Two Bacterial Arsenals: Evolution through Gene Losses in Facultative Endosymbionts
dc.creator.none.fl_str_mv Rollat-Farnier PA
Santos-Garcia D
Rao Q
Sagot MF
Silva FJ
Henri H
Zchori-Fein E
Latorre A
Moya A
Barbe V
Liu SS
Wang XW
Vavre F
Mouton L
author Rollat-Farnier PA
author_facet Rollat-Farnier PA
Santos-Garcia D
Rao Q
Sagot MF
Silva FJ
Henri H
Zchori-Fein E
Latorre A
Moya A
Barbe V
Liu SS
Wang XW
Vavre F
Mouton L
author_role author
author2 Santos-Garcia D
Rao Q
Sagot MF
Silva FJ
Henri H
Zchori-Fein E
Latorre A
Moya A
Barbe V
Liu SS
Wang XW
Vavre F
Mouton L
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv comparative genomics
Hamiltonella defensa
aphids
Bemisia tabaci
topic comparative genomics
Hamiltonella defensa
aphids
Bemisia tabaci
description Bacterial endosymbiosis is an important evolutionary process in insects, which can harbor both obligate and facultative symbionts. The evolution of these symbionts is driven by evolutionary convergence, and they exhibit among the tiniest genomes in prokaryotes. The large host spectrum of facultative symbionts and the high diversity of strategies they use to infect new hosts probably impact the evolution of their genome and explain why they undergo less severe genomic erosion than obligate symbionts. Candidatus Hamiltonella defensa is suitable for the investigation of the genomic evolution of facultative symbionts because the bacteria are engaged in specific relationships in two clades of insects. In aphids, H. defensa is found in several species with an intermediate prevalence and confers protection against parasitoids. In whiteflies, H. defensa is almost fixed in some species of Bemisia tabaci, which suggests an important role of and a transition toward obligate symbiosis. In this study, comparisons of the genome of H. defensa present in two B. tabaci species ( Middle East Asia Minor 1 and Mediterranean) and in the aphid Acyrthosiphon pisum revealed that they belong to two distinct clades and underwent specific gene losses. In aphids, it contains highly virulent factors that could allow protection and horizontal transfers. In whiteflies, the genome lost these factors and seems to have a limited ability to acquire genes. However it contains genes that could be involved in the production of essential nutrients, which is consistent with a primordial role for this symbiont. In conclusion, although both lineages of H. defensa have mutualistic interactions with their hosts, their genomes follow distinct evolutionary trajectories that reflect their phenotype and could have important consequences on their evolvability.
publishDate 2015
dc.date.none.fl_str_mv 2015
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://fisabio.portalinvestigacion.com/publicaciones/4668
url https://fisabio.portalinvestigacion.com/publicaciones/4668
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv OXFORD UNIV PRESS
publisher.none.fl_str_mv OXFORD UNIV PRESS
dc.source.none.fl_str_mv Genome Biology and Evolution
ISSN: 17596653
reponame:r-FISABIO. Repositorio Institucional de Producción Científica
instname:Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
instname_str Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana (FISABIO)
reponame_str r-FISABIO. Repositorio Institucional de Producción Científica
collection r-FISABIO. Repositorio Institucional de Producción Científica
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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