Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes

The Editorial Board of the Medicinal Chemistry section of the journal Molecules publishes here its first Editorial, which has been prepared by highlighting, in sub-editorials of about one hundred words, some selected recently published articles that may have a profound impact on drug discovery and t...

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Autores: Muñoz-Torrero López-Ibarra, Diego, Mangoni, Arduino A., Guillou, Catherine, Collina, Simona, Vanden Eynde, Jean Jacques, Rautio, Jarkko, Keseru, György M., Hulme, Christopher, Chibale, Kelly, Luque Garriga, F. Xavier, Karaman, Rafik, Gütschow, Michael, Liu, Hong, Ragno, Rino
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Institución:Universidad de Barcelona
Repositorio:Dipòsit Digital de la UB
OAI Identifier:oai:diposit.ub.edu:2445/120834
Acceso en línea:https://hdl.handle.net/2445/120834
Access Level:acceso abierto
Palabra clave:Química farmacèutica
Pharmaceutical chemistry
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spelling Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopesMuñoz-Torrero López-Ibarra, DiegoMangoni, Arduino A.Guillou, CatherineCollina, SimonaVanden Eynde, Jean JacquesRautio, JarkkoKeseru, György M.Hulme, ChristopherChibale, KellyLuque Garriga, F. XavierKaraman, RafikGütschow, MichaelLiu, HongRagno, RinoQuímica farmacèuticaPharmaceutical chemistryThe Editorial Board of the Medicinal Chemistry section of the journal Molecules publishes here its first Editorial, which has been prepared by highlighting, in sub-editorials of about one hundred words, some selected recently published articles that may have a profound impact on drug discovery and therapy. In particular, this editorial highlights new drug targets and mechanisms of action and new classes of drugs, as well as new therapeutic uses for known drugs or the involvement of known biological targets in new diseases. We also discuss some structural biology studies and new computational tools that may pave the way for the rational design or identification of more efficacious and safer drugs. Overall, the findings reported in these highlighted papers raise our hopes for the management of difficult-to-treat diseases that are posing a growing health threat, with new or repurposed drugs that overcome the limitations of currently applied therapies.MDPI2017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://hdl.handle.net/2445/120834Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)reponame:Dipòsit Digital de la UBinstname:Universidad de BarcelonaInglésReproducció del document publicat a: https://doi.org/10.3390/molecules22050743Molecules, 2017, vol. 22, num. 743https://doi.org/10.3390/molecules22050743cc-by (c) Muñoz-Torrero López-Ibarra, Diego et al., 2017http://creativecommons.org/licenses/by/3.0/esinfo:eu-repo/semantics/openAccessoai:diposit.ub.edu:2445/1208342026-05-27T06:46:51Z
dc.title.none.fl_str_mv Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes
title Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes
spellingShingle Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes
Muñoz-Torrero López-Ibarra, Diego
Química farmacèutica
Pharmaceutical chemistry
title_short Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes
title_full Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes
title_fullStr Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes
title_full_unstemmed Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes
title_sort Breakthroughs in Medicinal Chemistry: New targets and mechanisms, new drugs, new hopes
dc.creator.none.fl_str_mv Muñoz-Torrero López-Ibarra, Diego
Mangoni, Arduino A.
Guillou, Catherine
Collina, Simona
Vanden Eynde, Jean Jacques
Rautio, Jarkko
Keseru, György M.
Hulme, Christopher
Chibale, Kelly
Luque Garriga, F. Xavier
Karaman, Rafik
Gütschow, Michael
Liu, Hong
Ragno, Rino
author Muñoz-Torrero López-Ibarra, Diego
author_facet Muñoz-Torrero López-Ibarra, Diego
Mangoni, Arduino A.
Guillou, Catherine
Collina, Simona
Vanden Eynde, Jean Jacques
Rautio, Jarkko
Keseru, György M.
Hulme, Christopher
Chibale, Kelly
Luque Garriga, F. Xavier
Karaman, Rafik
Gütschow, Michael
Liu, Hong
Ragno, Rino
author_role author
author2 Mangoni, Arduino A.
Guillou, Catherine
Collina, Simona
Vanden Eynde, Jean Jacques
Rautio, Jarkko
Keseru, György M.
Hulme, Christopher
Chibale, Kelly
Luque Garriga, F. Xavier
Karaman, Rafik
Gütschow, Michael
Liu, Hong
Ragno, Rino
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Química farmacèutica
Pharmaceutical chemistry
topic Química farmacèutica
Pharmaceutical chemistry
description The Editorial Board of the Medicinal Chemistry section of the journal Molecules publishes here its first Editorial, which has been prepared by highlighting, in sub-editorials of about one hundred words, some selected recently published articles that may have a profound impact on drug discovery and therapy. In particular, this editorial highlights new drug targets and mechanisms of action and new classes of drugs, as well as new therapeutic uses for known drugs or the involvement of known biological targets in new diseases. We also discuss some structural biology studies and new computational tools that may pave the way for the rational design or identification of more efficacious and safer drugs. Overall, the findings reported in these highlighted papers raise our hopes for the management of difficult-to-treat diseases that are posing a growing health threat, with new or repurposed drugs that overcome the limitations of currently applied therapies.
publishDate 2017
dc.date.none.fl_str_mv 2017
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/120834
url https://hdl.handle.net/2445/120834
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.3390/molecules22050743
Molecules, 2017, vol. 22, num. 743
https://doi.org/10.3390/molecules22050743
dc.rights.none.fl_str_mv cc-by (c) Muñoz-Torrero López-Ibarra, Diego et al., 2017
http://creativecommons.org/licenses/by/3.0/es
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc-by (c) Muñoz-Torrero López-Ibarra, Diego et al., 2017
http://creativecommons.org/licenses/by/3.0/es
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)
reponame:Dipòsit Digital de la UB
instname:Universidad de Barcelona
instname_str Universidad de Barcelona
reponame_str Dipòsit Digital de la UB
collection Dipòsit Digital de la UB
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15.301603

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