Absolute Configuration of the Invasive Mealybug Delottococcus aberiae (De Lotto) Sex Pheromone: Synthesis and Bioassay of Both Enantiomers

[EN] The mealybug Delottococcus aberiae (De Lotto) (Hemiptera: Pseudococcidae) is an invasive pest reported in Europe at the end of the first decade of the 2000s, causing severe damage to citrus production in eastern Spain. In a previous work, (4,5,5-trimethyl-3-methylenecyclopent-1-en-1-yl)methyl a...

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Detalles Bibliográficos
Autores: Marzo Bargues, Javier, Navarro Fuertes, Ismael, Abad-Somovilla, Antonio, Vacas, Sandra|||0000-0001-6911-1647, Primo Millo, Jaime|||0000-0003-2254-8184, Navarro-Llopis, Vicente|||0000-0003-3030-3304
Tipo de recurso: artículo
Fecha de publicación:2024
País:España
Institución:Universitat Politècnica de València (UPV)
Repositorio:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Idioma:inglés
OAI Identifier:oai:riunet.upv.es:10251/219872
Acceso en línea:https://riunet.upv.es/handle/10251/219872
Access Level:acceso abierto
Palabra clave:D. aberiae
Diastereomeric resolution
Enantiomers
Insect attractant
Necrodol skeleton
Pheromone
Descripción
Sumario:[EN] The mealybug Delottococcus aberiae (De Lotto) (Hemiptera: Pseudococcidae) is an invasive pest reported in Europe at the end of the first decade of the 2000s, causing severe damage to citrus production in eastern Spain. In a previous work, (4,5,5-trimethyl-3-methylenecyclopent-1-en-1-yl)methyl acetate was identified as the sex pheromone emitted by females, a new compound with an unusual ß-necrodol skeleton possessing one stereocenter. This compound was assigned to the (-)-enantiomer but the absolute configuration was then not reported. In the present study, enantiomeric pure samples of both enantiomers were synthesized. X-ray diffraction analysis allowed the (-)-enantiomer, identical to the one emitted by virgin D. aberiae females, to be unequivocally identified as (-)-(R)-(4,5,5-trimethyl-3-methylenecyclopent-1-en-1-yl)methyl acetate. Bioassays carried out to test the activity of both enantiomers under field conditions suggest that the presence of the (+)-(S)-enantiomer has detrimental effects on the activity of the racemates.