Bioprocesses for 2-phenylethanol and 2-phenylethyl acetate production

2-Phenylethanol (2-PE) and 2-phenethyl acetate (2-PEA) are valuable generally recognized as safe flavoring agents widely used in industry. Perfumes, pharmaceuticals, polishes, and personal care products, are some of the final products using these compounds as additives due to their rose-like odor. A...

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Detalhes bibliográficos
Autores: Martinez Avila, Oscar Mauricio|||0000-0001-7561-4013, Sánchez, Antoni|||0000-0003-4254-8528, Font, Xavier|||0000-0003-4981-7436, Barrena, Raquel|||0000-0002-6077-7765
Tipo de documento: artigo
Data de publicação:2018
País:España
Recursos:Universitat Autònoma de Barcelona
Repositório:Dipòsit Digital de Documents de la UAB
Idioma:inglês
OAI Identifier:oai:ddd.uab.cat:322576
Acesso em linha:https://ddd.uab.cat/record/322576
https://dx.doi.org/urn:doi:10.1007/s00253-018-9384-8
Access Level:Acceso aberto
Palavra-chave:2-phenethyl acetate
2-phenylethanol
Aroma compounds
Biotransformation
Ehrlich pathway
Descrição
Resumo:2-Phenylethanol (2-PE) and 2-phenethyl acetate (2-PEA) are valuable generally recognized as safe flavoring agents widely used in industry. Perfumes, pharmaceuticals, polishes, and personal care products, are some of the final products using these compounds as additives due to their rose-like odor. Also, 2-PE is used in disinfectants, pest control, and cleaning products due to its biocide capability. Although most of these additives production are derived from chemical synthesis, the current trend of consumers to prefer natural products has contributed to the development of biotechnological approaches as an alternative way to obtain natural 2-PE and 2-PEA. The most efficient route to bioproduce these compounds is through the bioconversion of L-phenylalanine via the Ehrlich pathway, and most of the advances have been focused on the development of this process. This review compiles the most recent developments in the biotechnological production of 2-PE and 2-PEA, indicating the most studied strains producing 2-PE and 2-PEA, the current advances in the in situ product recovery in liquid systems, an overview of the strain developments, and the progress in the use of residue-based systems. Future research should address the need for more sustainable and economic systems such as those using wastes as raw materials, as well as the scale-up of the proposed technologies.