Clinical signs, diagnostic imaging and histopathology in a dog with granulomatous meningoencephalitis manifested as a polyneuropathy

An 11-year-old, female, neutered labrador retriever with a history of chronic and progressive right hindlimb lameness and facial asymmetry was referred for brain and lumbosacral magnetic resonance imaging and cerebrospinal fluid analysis. Multifocal non-enhancing T2-weighted images of hyperintense l...

Descripción completa

Detalles Bibliográficos
Autores: Benito Benito, Miguel, Portero Fuentes, Miriam, Manso Díaz, Gabriel, Sánchez Madonado, Belén, Pérez Díaz, Carmen
Tipo de recurso: artículo
Fecha de publicación:2022
País:España
Institución:Universidad Complutense de Madrid (UCM)
Repositorio:Docta Complutense
Idioma:inglés
OAI Identifier:oai:docta.ucm.es:20.500.14352/71476
Acceso en línea:https://hdl.handle.net/20.500.14352/71476
Access Level:acceso abierto
Palabra clave:Animales de compañía
Patología veterinaria
3109.07 Patología
Descripción
Sumario:An 11-year-old, female, neutered labrador retriever with a history of chronic and progressive right hindlimb lameness and facial asymmetry was referred for brain and lumbosacral magnetic resonance imaging and cerebrospinal fluid analysis. Multifocal non-enhancing T2-weighted images of hyperintense lesions were observed in the caudate nuclei and medulla oblongata. The right oculomotor nerve was markedly enlarged and showed marked enhancement on T1-weighted images after contrast injection, and there was diffuse enlargement of the sciatic and femoral nerves in the right hindlimb. Cerebrospinal fluid analysis showed a mixed pleocytosis. Histopathology revealed granulomatous inflammation affecting the brain, oculomotor and pelvic limb nerves, consistent with a diagnosis of granulomatous meningoencephalomyelitis.