Effects of Psychiatric Comorbidity on Treatment Outcome in Patients Undergoing Diamorphine or Methadone Maintenance Treatment

Background: Comorbid psychiatric disorders among opioid-dependent patients are associated with several negative outcome factors. However, outcomes of maintenance treatment have not been sufficiently established, and no evidence is available with respect to heroin-assisted treatment (HAT). Methods: F...

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Authors: Schäfer, Ingo, Eiroá Orosa, Francisco José, Verthein, Uwe, Dilg, Christoph, Haasen, Christian, Reimer, Jens
Format: article
Status:Versión aceptada para publicación
Publication Date:2010
Country:España
Institution:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repository:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/120731
Online Access:https://hdl.handle.net/2445/120731
Access Level:Open access
Keyword:Comorbiditat
Desintoxicació de les drogues
Metadona
Heroïna
Comorbidity
Drug detoxification
Methadone hydrochloride
Heroin
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spelling Effects of Psychiatric Comorbidity on Treatment Outcome in Patients Undergoing Diamorphine or Methadone Maintenance TreatmentSchäfer, IngoEiroá Orosa, Francisco JoséVerthein, UweDilg, ChristophHaasen, ChristianReimer, JensComorbiditatDesintoxicació de les droguesMetadonaHeroïnaComorbidityDrug detoxificationMethadone hydrochlorideHeroinBackground: Comorbid psychiatric disorders among opioid-dependent patients are associated with several negative outcome factors. However, outcomes of maintenance treatment have not been sufficiently established, and no evidence is available with respect to heroin-assisted treatment (HAT). Methods: For patients in the German heroin trial outcome measures were analyzed for HAT versus methadone maintenance treatment (MMT) both for patients with and without a comorbid diagnosis according to CIDI. Results: 47.2% of the sample had at least one comorbid psychiatric diagnosis, mainly neurotic, stress-related or somatoform (F4) or affective (F3) disorders. HAT had a better outcome than MMT concerning improvement of health and reduction of illicit drug use in both comorbid and non-comorbid patients, but weaker effects were found in the comorbid group. Conclusions:The better outcome of HAT also in comorbid patients suggests that psychiatric comorbidity should be an inclusion criterion for HAT. The weaker advantage of HAT may be due to pharmacological or methodological reasons.Karger2018201820102018info:eu-repo/semantics/articleinfo:eu-repo/semantics/acceptedVersion17 p.application/pdfhttps://hdl.handle.net/2445/120731Articles publicats en revistes (Psicologia Clínica i Psicobiologia)reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésVersió postprint del document publicat a: https://doi.org/10.1159/000274177Psychopathology, 2010, vol. 43, num. 2, p. 88-95https://doi.org/10.1159/000274177(c) Karger, 2010info:eu-repo/semantics/openAccessoai:recercat.cat:2445/1207312026-05-29T05:05:01Z
dc.title.none.fl_str_mv Effects of Psychiatric Comorbidity on Treatment Outcome in Patients Undergoing Diamorphine or Methadone Maintenance Treatment
title Effects of Psychiatric Comorbidity on Treatment Outcome in Patients Undergoing Diamorphine or Methadone Maintenance Treatment
spellingShingle Effects of Psychiatric Comorbidity on Treatment Outcome in Patients Undergoing Diamorphine or Methadone Maintenance Treatment
Schäfer, Ingo
Comorbiditat
Desintoxicació de les drogues
Metadona
Heroïna
Comorbidity
Drug detoxification
Methadone hydrochloride
Heroin
title_short Effects of Psychiatric Comorbidity on Treatment Outcome in Patients Undergoing Diamorphine or Methadone Maintenance Treatment
title_full Effects of Psychiatric Comorbidity on Treatment Outcome in Patients Undergoing Diamorphine or Methadone Maintenance Treatment
title_fullStr Effects of Psychiatric Comorbidity on Treatment Outcome in Patients Undergoing Diamorphine or Methadone Maintenance Treatment
title_full_unstemmed Effects of Psychiatric Comorbidity on Treatment Outcome in Patients Undergoing Diamorphine or Methadone Maintenance Treatment
title_sort Effects of Psychiatric Comorbidity on Treatment Outcome in Patients Undergoing Diamorphine or Methadone Maintenance Treatment
dc.creator.none.fl_str_mv Schäfer, Ingo
Eiroá Orosa, Francisco José
Verthein, Uwe
Dilg, Christoph
Haasen, Christian
Reimer, Jens
author Schäfer, Ingo
author_facet Schäfer, Ingo
Eiroá Orosa, Francisco José
Verthein, Uwe
Dilg, Christoph
Haasen, Christian
Reimer, Jens
author_role author
author2 Eiroá Orosa, Francisco José
Verthein, Uwe
Dilg, Christoph
Haasen, Christian
Reimer, Jens
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Comorbiditat
Desintoxicació de les drogues
Metadona
Heroïna
Comorbidity
Drug detoxification
Methadone hydrochloride
Heroin
topic Comorbiditat
Desintoxicació de les drogues
Metadona
Heroïna
Comorbidity
Drug detoxification
Methadone hydrochloride
Heroin
description Background: Comorbid psychiatric disorders among opioid-dependent patients are associated with several negative outcome factors. However, outcomes of maintenance treatment have not been sufficiently established, and no evidence is available with respect to heroin-assisted treatment (HAT). Methods: For patients in the German heroin trial outcome measures were analyzed for HAT versus methadone maintenance treatment (MMT) both for patients with and without a comorbid diagnosis according to CIDI. Results: 47.2% of the sample had at least one comorbid psychiatric diagnosis, mainly neurotic, stress-related or somatoform (F4) or affective (F3) disorders. HAT had a better outcome than MMT concerning improvement of health and reduction of illicit drug use in both comorbid and non-comorbid patients, but weaker effects were found in the comorbid group. Conclusions:The better outcome of HAT also in comorbid patients suggests that psychiatric comorbidity should be an inclusion criterion for HAT. The weaker advantage of HAT may be due to pharmacological or methodological reasons.
publishDate 2010
dc.date.none.fl_str_mv 2010
2018
2018
2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/acceptedVersion
format article
status_str acceptedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/120731
url https://hdl.handle.net/2445/120731
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Versió postprint del document publicat a: https://doi.org/10.1159/000274177
Psychopathology, 2010, vol. 43, num. 2, p. 88-95
https://doi.org/10.1159/000274177
dc.rights.none.fl_str_mv (c) Karger, 2010
info:eu-repo/semantics/openAccess
rights_invalid_str_mv (c) Karger, 2010
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 17 p.
application/pdf
dc.publisher.none.fl_str_mv Karger
publisher.none.fl_str_mv Karger
dc.source.none.fl_str_mv Articles publicats en revistes (Psicologia Clínica i Psicobiologia)
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,812429

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