Neuromodulation-induced prehabilitation to leverage neuroplasticity before brain tumor surgery: a single-cohort feasibility trial protocol

Neurosurgery for brain tumors needs to find a complex balance between the effective removal of targeted tissue and the preservation of surrounding brain areas. Neuromodulation-induced cortical prehabilitation (NICP) is a promising strategy that combines temporary inhibition of critical areas (virtua...

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Detalles Bibliográficos
Autores: Boccuni, Leonardo, Abellaneda‑Pérez, Kilian, Martín-Fernández, Jesús, Leno-Colorado, David, Roca-Ventura, Alba, Prats Bisbe, Alba, Buloz-Osorio, Edgar Antonio, Bartrés Faz, David, Bargallo, Nuria, Cabello-Toscano, María, Pariente, José Carlos, Muñoz-Moreno, Emma, Trompetto, Carlo, Marinelli, Lucio, Villalba-Martinez, Gloria, Duffau, Hugues, Pascual Leone, Álvaro, Tormos Muñoz, José María, Neuromodulation-Induced Prehabilitation in Brain Tumour Surgery Group
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universidad Católica de Valencia San Vicente Mártir
Repositorio:RIUCV. Repositorio de la Universidad Católica de Valencia San Vicente Mártir
Idioma:inglés
OAI Identifier:oai:riucv.ucv.es:20.500.12466/4411
Acceso en línea:http://hdl.handle.net/20.500.12466/4411
Access Level:acceso abierto
Palabra clave:Brain tumor
Neuro-oncology
Prehabilitation
Neuromodulation
Neurorehabilitation
Neurosurgery
Neuroplasticity
Clinical trial
32 Ciencias Médicas
Descripción
Sumario:Neurosurgery for brain tumors needs to find a complex balance between the effective removal of targeted tissue and the preservation of surrounding brain areas. Neuromodulation-induced cortical prehabilitation (NICP) is a promising strategy that combines temporary inhibition of critical areas (virtual lesion) with intensive behavioral training to foster the activation of alternative brain resources. By progressively reducing the functional relevance of targeted areas, the goal is to facilitate resection with reduced risks of neurological sequelae. However, it is still unclear which modality (invasive vs. non-invasive neuromodulation) and volume of therapy (behavioral training) may be optimal in terms of feasibility and efficacy.

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