Tear film constituents and medicines for eyes investigated as Langmuir films

The tear flm has an important role on the quality of the vision process and is of importance in the felds of ophthalmology and optometry. The lipid layer, the outermost part of the tear flm, can be investigated with the Langmuir technique, as well as the interaction of components of the aqueous part...

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Detalles Bibliográficos
Autor: Torrent Burgués, Juan|||0000-0002-4952-736X
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/388188
Acceso en línea:https://hdl.handle.net/2117/388188
https://dx.doi.org/10.1007/s12668-023-01112-2
Access Level:acceso abierto
Palabra clave:Membranes (Biology)
Thin films
Tear film
Lipid layer
Langmuir film
Dry eye
Artificial tear
Lipid artificial tear
Membranes (Biologia)
Capes fines
Àrees temàtiques de la UPC::Ciències de la visió::Biologia ocular
Descripción
Sumario:The tear flm has an important role on the quality of the vision process and is of importance in the felds of ophthalmology and optometry. The lipid layer, the outermost part of the tear flm, can be investigated with the Langmuir technique, as well as the interaction of components of the aqueous part of the tear flm with those of the lipid layer. Dysfunctions in the stability and composition of the tear flm are the causes of eye diseases, as the dry eye syndrome. For the treatment of this disease, the artifcial tears are used, and one type of them are the lipid tears, which can be investigated with the Langmuir technique. This technique can also be used to investigate the infuence on the lipid layer of other artifcial tear components or medicines instilled in the eye. This review presents investigations where the Langmuir technique has been used in relation with the tear flm. In particular, the surface properties of natural tears and of four commercial lipid-containing artifcial tears have been reported and discussed in connection with their composition.