Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice

The aim of this research was to explore the genetic parameters associated with environmental variability for litter size (LS), litter weight (LW) and mean individual birth weight (IW) in mice before canalisation. The analyses were conducted on an experimental mice population designed to reduce envir...

Descripción completa

Detalles Bibliográficos
Autores: Gutiérrez, Juan Pablo, Nieto, Blanca, Piqueras, Pepa, Ibañez Escriche, Noelia, Salgado, Concepción
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2006
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10459.1/49282
Acceso en línea:https://doi.org/10.1051/gse:2006014
http://hdl.handle.net/10459.1/49282
Access Level:acceso abierto
Palabra clave:Canalisation
Variability
Mice
id ES_5cbf9c2b06da012e6a9b5b2e464cc799
oai_identifier_str oai:recercat.cat:10459.1/49282
network_acronym_str ES
network_name_str España
repository_id_str
spelling Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in miceGutiérrez, Juan PabloNieto, BlancaPiqueras, PepaIbañez Escriche, NoeliaSalgado, ConcepciónCanalisationVariabilityMiceThe aim of this research was to explore the genetic parameters associated with environmental variability for litter size (LS), litter weight (LW) and mean individual birth weight (IW) in mice before canalisation. The analyses were conducted on an experimental mice population designed to reduce environmental variability for LS. The analysed database included 1976 records for LWand IWand 4129 records for LS. The total number of individuals included in the analysed pedigree was 3997. Heritabilities estimated for the traits under an initial exploratory approach varied from 0.099 to 0.101 for LS, from 0.112 to 0.148 for LW and from 0.028 to 0.033 for IW. The means of the posterior distribution of the heritability under a Bayesian approach were the following: 0.10 (LS), 0.13 (LW) and 0.03 (IW). In general, the heritabilities estimated under the initial exploratory approach for the environmental variability of the analysed traits were low. Genetic correlations estimated between the trait and its variability reached values of –0.929 (LS), –0.815 (LW) and 0.969 (IW). The results presented here for the first time in mice may suggest a genetic basis for variability of the evaluated traits, thus opening the possibility to be implemented in selection schemes.BioMed Central2006info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://doi.org/10.1051/gse:2006014http://hdl.handle.net/10459.1/49282reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a https://doi.org/10.1051/gse:2006014Genetics Selection Evolution, 2006, vol. 38, núm. 5, p. 445-462cc-by (c) Gutiérrez et al., 2006info:eu-repo/semantics/openAccesshttp://creativecommons.org/licenses/by/3.0/es/oai:recercat.cat:10459.1/492822026-05-29T05:05:01Z
dc.title.none.fl_str_mv Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice
title Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice
spellingShingle Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice
Gutiérrez, Juan Pablo
Canalisation
Variability
Mice
title_short Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice
title_full Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice
title_fullStr Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice
title_full_unstemmed Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice
title_sort Genetic parameters for canalisation analysis of litter size and litter weight traits at birth in mice
dc.creator.none.fl_str_mv Gutiérrez, Juan Pablo
Nieto, Blanca
Piqueras, Pepa
Ibañez Escriche, Noelia
Salgado, Concepción
author Gutiérrez, Juan Pablo
author_facet Gutiérrez, Juan Pablo
Nieto, Blanca
Piqueras, Pepa
Ibañez Escriche, Noelia
Salgado, Concepción
author_role author
author2 Nieto, Blanca
Piqueras, Pepa
Ibañez Escriche, Noelia
Salgado, Concepción
author2_role author
author
author
author
dc.subject.none.fl_str_mv Canalisation
Variability
Mice
topic Canalisation
Variability
Mice
description The aim of this research was to explore the genetic parameters associated with environmental variability for litter size (LS), litter weight (LW) and mean individual birth weight (IW) in mice before canalisation. The analyses were conducted on an experimental mice population designed to reduce environmental variability for LS. The analysed database included 1976 records for LWand IWand 4129 records for LS. The total number of individuals included in the analysed pedigree was 3997. Heritabilities estimated for the traits under an initial exploratory approach varied from 0.099 to 0.101 for LS, from 0.112 to 0.148 for LW and from 0.028 to 0.033 for IW. The means of the posterior distribution of the heritability under a Bayesian approach were the following: 0.10 (LS), 0.13 (LW) and 0.03 (IW). In general, the heritabilities estimated under the initial exploratory approach for the environmental variability of the analysed traits were low. Genetic correlations estimated between the trait and its variability reached values of –0.929 (LS), –0.815 (LW) and 0.969 (IW). The results presented here for the first time in mice may suggest a genetic basis for variability of the evaluated traits, thus opening the possibility to be implemented in selection schemes.
publishDate 2006
dc.date.none.fl_str_mv 2006
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://doi.org/10.1051/gse:2006014
http://hdl.handle.net/10459.1/49282
url https://doi.org/10.1051/gse:2006014
http://hdl.handle.net/10459.1/49282
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a https://doi.org/10.1051/gse:2006014
Genetics Selection Evolution, 2006, vol. 38, núm. 5, p. 445-462
dc.rights.none.fl_str_mv cc-by (c) Gutiérrez et al., 2006
info:eu-repo/semantics/openAccess
http://creativecommons.org/licenses/by/3.0/es/
rights_invalid_str_mv cc-by (c) Gutiérrez et al., 2006
http://creativecommons.org/licenses/by/3.0/es/
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv BioMed Central
publisher.none.fl_str_mv BioMed Central
dc.source.none.fl_str_mv reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869408939418845184
score 15,811543

Similares en LA Referencia