MRI white matter lesion segmentation using an ensemble of neural networks and overcomplete patch-based voting

[EN] Accurate quantification of white matter hyperintensities (WMH) from Magnetic Resonance Imaging (MRI) is a valuable tool for the analysis of normal brain ageing or neurodegeneration. Reliable automatic extraction of WMH lesions is challenging due to their heterogeneous spatial occurrence, their...

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Bibliographic Details
Authors: Manjón Herrera, José Vicente|||0000-0001-6640-927X, Coupe, Pierrick, Raniga, Parnesh, Xia, Ying, Desmond, Patricia, Fripp, Jurgen, Salvado, Olivier
Format: article
Publication Date:2018
Country:España
Institution:Universitat Politècnica de València (UPV)
Repository:RiuNet. Repositorio Institucional de la Universitat Politécnica de Valéncia
Language:English
OAI Identifier:oai:riunet.upv.es:10251/147544
Online Access:https://riunet.upv.es/handle/10251/147544
Access Level:Open access
Keyword:Lesion segmentation
MRI
Brain
Patch-Based
Neural network
Ensemble
FISICA APLICADA
Description
Summary:[EN] Accurate quantification of white matter hyperintensities (WMH) from Magnetic Resonance Imaging (MRI) is a valuable tool for the analysis of normal brain ageing or neurodegeneration. Reliable automatic extraction of WMH lesions is challenging due to their heterogeneous spatial occurrence, their small size and their diffuse nature. In this paper, we present an automatic method to segment these lesions based on an ensemble of overcomplete patch-based neural networks. The proposed method successfully provides accurate and regular segmentations due to its overcomplete nature while minimizing the segmentation error by using a boosted ensemble of neural networks. The proposed method compared favourably to state of the art techniques using two different neurodegenerative datasets. (C) 2018 Elsevier Ltd. All rights reserved.