Is asthma control more than just an absence of symptoms? An expert consensus statement

Purpose: Definitions and measures of asthma control used in clinical trials and in clinical practice vary considerably. There is also misalignment between patients and healthcare professionals (HCPs) in terms of understanding and managing asthma control. This study aimed to progress towards a consen...

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Detalles Bibliográficos
Autores: Canonica, GW, Spanevello, A, Ribas, CD, Blakey, JD, Garcia, G, Inoue, H, Dalcolmo, M, Yang, D, Mokashi, S, Kurne, A, Llano, LPD, Butta, AK
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2022
País:España
Institución:Institut d'Investigació i Innovació Parc Taulí (I3PT)
Repositorio:r-I3PT. Repositorio Institucional Producción Científica del Institut d'Investigació i Innovació Parc Taulí
OAI Identifier:oai:i3pt.fundanetsuite.com:p1244
Acceso en línea:https://i3pt.portalinvestigacion.com/publicaciones/1244
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85137364778&doi=10.1016%2fj.rmed.2022.106942&partnerID=40&md5=f3b0a86637e5452df331f81da2fa4eae
Access Level:acceso abierto
Palabra clave:Asthma
Asthma control
Delphi consensus
Exacerbations
Quality of life
Symptom control
Descripción
Sumario:Purpose: Definitions and measures of asthma control used in clinical trials and in clinical practice vary considerably. There is also misalignment between patients and healthcare professionals (HCPs) in terms of understanding and managing asthma control. This study aimed to progress towards a consensus definition of asthma control, and evaluate disparities between HCP and patient perspectives. Basic procedures: A two-stage Delphi questionnaire involving asthma specialists sought to identify areas of consensus on aspects of asthma control in clinical practice. Results were compared with those of a structured literature review to assess if existing guidance and measures of asthma control used in studies correlated with practice. Eighty-two panelists took part in the Delphi questionnaire. The structured literature review included 185 manuscripts and 31 abstracts. Main findings: Panelists agreed that there was no standard definition of asthma control, confirmed by a total of 19 different composite consensus/guideline definitions and/or validated measures of control being identified across the Delphi study and literature review. Panelists agreed on the positive associations of well-controlled asthma with patient outcomes, but not on the components or thresholds of a working definition of control. Principal conclusions: A universally accepted definition and measure of asthma control that is utilized and understood by patients, HCPs, and researchers is required.