We employed Mendelian randomization (MR) to evaluate the causal relationship between leukocyte telomere length (LTL) and amyotrophic lateral sclerosis (ALS) with summary statistics from genome-wide association studies (n = ~ 38,000 for LTL and ~ 81,000 for ALS in the European population; n = ~ 23,00...
Detalles Bibliográficos
| Autores: |
Gao, Yixin,
Wang, Ting|||0000-0002-6800-242X,
Yu, Xinghao,
Ferrari, Raffaele,
Hernandez, Dena G.|||0000-0002-0188-9927,
Nalls, Michael A.,
Rohrer, Jonathan D.,
Ramasamy, Adaikalavan|||0000-0002-7598-2892,
Kwok, John B.J.,
Dobson-Stone, Carol,
Brooks, William S.,
Schofield, Peter R.|||0000-0003-2967-9662,
Halliday, Glenda M.,
Hodges, John R.,
Piguet, Olivier,
Bartley, Lauren,
Thompson, Elizabeth,
Haan, Eric,
Hernández, Isabel|||0000-0001-8119-393X,
Ruiz Laza, Agustín|||0000-0003-2633-2495,
Boada, Mercè|||0000-0003-2617-3009,
Borroni, Barbara|||0000-0001-9340-9814,
Padovani, Alessandro|||0000-0002-0119-3639,
Cruchaga, Carlos|||0000-0002-0276-2899,
Cairns, Nigel J.,
Benussi, Luisa|||0000-0003-2836-8141,
Binetti, Giuliano|||0000-0003-2759-5844,
Ghidoni, Roberta|||0000-0002-7691-1957,
Forloni, Gianluigi,
Albani, Diego|||0000-0002-7050-6723,
Galimberti, Daniela|||0000-0002-9284-5953,
Fenoglio, Chiara|||0000-0001-6332-4721,
Serpente, Maria,
Scarpini, Elio|||0000-0002-6395-2119,
Clarimón, Jordi|||0000-0002-6824-6942,
Lleó, Alberto|||0000-0002-2568-5478,
Blesa, Rafael|||0000-0003-4026-2884,
Waldö, Maria Landqvist,
Nilsson, Karin,
Nilsson, Christer,
Mackenzie, Ian R.A.,
Hsiung, Ging-Yuek R.,
Mann, David M. A.,
Grafman, Jordan,
Morris, Christopher M.,
Attems, Johannes|||0000-0003-1636-1700,
Griffiths, Timothy D.,
McKeith, Ian G.,
Thomas, Alan J.,
Pietrini, Pietro,
Huey, Edward D.,
Wassermann, E. M.,
Baborie, Atik,
Jaros, Evelyn,
Tierney, Michael C.,
Pastor, Pau|||0000-0002-7493-8777,
Razquín, Cristina|||0000-0003-3480-2645,
Ortega-Cubero, Sara|||0000-0003-0520-9439,
Alonso, Elena,
Perneczky, Robert|||0000-0003-1981-7435,
Diehl-Schmid, Janine|||0000-0002-7745-1382,
Alexopoulos, Panagiotis|||0000-0002-9047-6365,
Kurz, Alexander,
Rainero, Innocenzo|||0000-0001-6074-9628,
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Pinessi, Lorenzo,
Rogaeva, Ekaterina,
St George Hyslop, Peter|||0000-0003-0796-7209,
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Tagliavini, Fabrizio|||0000-0003-1039-7315,
Giaccone, Giorgio|||0000-0002-4803-0802,
Rowe, James B.,
Schlachetzki, Johannes C. M.,
Uphill, J.,
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Trojanowski, John Q.|||0000-0002-9239-8794,
Van der Zee, Julie|||0000-0003-4381-8040,
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Cappa, Stefano F.,
Leber, Isabelle,
Hannequin, Didier,
Golfier, Véronique,
Vercelletto, Martine,
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Nacmias, Benedetta|||0000-0001-9338-9040,
Sorbi, Sandro|||0000-0002-0380-6670,
Bagnoli, Silvia,
Piaceri, Irene|||0000-0001-6787-2223,
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Riemenschneider, Matthias,
Mayhaus, Manuel,
Ibach, Bernd,
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Pichler, Sabrina,
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Warren, Jason D.,
Spillantini, Maria Grazia,
Morris, Huw|||0000-0002-5473-3774,
Rizzu, Patrizia,
Heutink, Peter|||0000-0001-5218-1737,
Snowden, Julie S.,
Rollinson, Sara|||0000-0002-0921-4318,
Richardson, Anna,
Gerhard, Alexander,
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Maletta, Raffaele|||0000-0002-0758-1835,
Frangipane, Francesca,
Cupidi, Chiara,
Bernardi, Livia,
Anfossi, Maria,
Gallo, Maura,
Conidi, Maria Elena,
Smirne, Nicoletta,
Rademakers, Rosa,
Baker, Matt,
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Graff-Radford, Neill R.,
Petersen, Ronald C.,
Knopman, David,
Josephs, Keith A.,
Boeve, Bradley,
Parisi, Joseph E.,
Seeley, William W.,
Miller, Bruce L.|||0000-0002-2152-4220,
Karydas, Anna M.,
Rosen, Howard,
van Swieten, John C.,
Dopper, Elise G. P.,
Seelaar, Harro|||0000-0003-1989-7527,
Pijnenburg, Yolande|||0000-0003-2464-1905,
Scheltens, Philip|||0000-0002-1046-6408,
Logroscino, Giancarlo|||0000-0003-0423-3242,
Capozzo, Rosa|||0000-0002-7672-8669,
Novelli, Valeria,
Puca, Annibale A.,
Franceschi, Massimo,
Postiglione, Alfredo,
Milan, Graziella,
Sorrentino, Paolo,
Kristiansen, Mark,
Chiang, Huei-Hsin,
Graff, Caroline|||0000-0002-9949-2951,
Pasquier, Florence|||0000-0001-9880-9788,
Rollin, Adeline,
Deramecourt, Vincent,
Lebouvier, Thibaud,
Kapogiannis, Dimitrios,
Ferrucci, Luigi,
Pickering-Brown, S.|||0000-0003-1561-6054,
Singleton, Andrew B.|||0000-0001-5606-700X,
Hardy, John|||0000-0002-3122-0423,
Momeni, Parastoo,
Zhao, Huashuo,
Zeng, Ping |
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| Tipo de recurso: | artículo
|
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| Fecha de publicación: | 2020 |
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| País: | España |
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| Institución: | Universitat Autònoma de Barcelona |
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| Repositorio: | Dipòsit Digital de Documents de la UAB |
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| Idioma: | inglés |
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| OAI Identifier: | oai:ddd.uab.cat:283718 |
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| Acceso en línea: | https://ddd.uab.cat/record/283718
https://dx.doi.org/urn:doi:10.1038/s41598-020-68848-9
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| Access Level: | acceso abierto |
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| Palabra clave: | Computational biology and bioinformatics
Genetics
Medical research
Neurology
Risk factors |
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