Reliability of a novel electro-medical device for wheal size measurement in allergy skin testing: An exploratory clinical trial

Skin prick testing (SPT) is the cornerstone of IgE-mediated allergy diagnosis,1 due to its high sensitivity and specificity.2 However, a uniform method for wheal measurement does not exist. Ansotegui et al.2 recommends to measure wheals in millimeters with a ruler, in many centers they are outlined...

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Autores: Morales-Palacios, M. P. (María de la Paz)|||/items/35dada0b-1b90-4d06-9e8f-250aac9a4197, Nuñez-Cordoba, J.M. (Jorge M.)|||/items/646d6eb5-e96f-43cb-8457-ab4e3a5a8bec, Tejero, E. (Eduardo)|||/items/0e172149-0bb4-450a-a937-556f237c4aa3, Matellanes, O. (Óscar)|||/items/8db92e54-f99b-4542-956a-ebeb75ac1fee, Quan, P.L. (Paola Leonor)|||/items/8655ba51-59ec-4749-b78a-f983df154310, Carvallo, Á. (Álvaro)|||/items/2d9c286f-e849-4d26-9e03-7eec49008d82, Sánchez-Fernández, S. (Sergio)|||/items/a2db881b-24db-4cf9-a8e6-22bb9944ff6e, Urtasun, M. (Maite)|||/items/f1110999-90d2-4eb0-be3f-ee447ff5b976, Larrea, C. (Carla)|||/items/350802e3-85ab-4a0c-a5d8-dd7caf7bb020, Iñiguez, M.T. (María Teresa)|||/items/9268202d-eb7a-4bf9-b78d-725770390e22, Giménez, R. (Rosa)|||/items/cdceecc7-e51d-47a6-9fab-37beca1bf26c, Goikoetxea-Lapresa, M.J. (María José)|||/items/c4c0994c-57d1-4759-b2af-c8ee1c5cab5b, D'Amelio-Garofalo, C.M. (Carmen Mariana)|||/items/5bfae2e4-7aca-4750-8c87-e230486112cd, Ferrer-Puga, M. (Marta)|||/items/ab9d3fc5-5095-4f28-8018-f157d8c9fce0, Gastaminza-Lasarte, G. (Gabriel)|||/items/9c84d89c-8a88-43cc-8336-fbc6cbf1ea77
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universidad de Navarra
Repositorio:Dadun. Depósito Académico Digital de la Universidad de Navarra
Idioma:inglés
OAI Identifier:oai:dadun.unav.edu:10171/66086
Acceso en línea:https://hdl.handle.net/10171/66086
Access Level:acceso abierto
Palabra clave:Allergy
Automated measurement
Clinical trial
Diagnosis
Prick test
Descripción
Sumario:Skin prick testing (SPT) is the cornerstone of IgE-mediated allergy diagnosis,1 due to its high sensitivity and specificity.2 However, a uniform method for wheal measurement does not exist. Ansotegui et al.2 recommends to measure wheals in millimeters with a ruler, in many centers they are outlined with a pen and transfer by tape to a paper and then measured. Subsequently, the specialist is able to manually measure the maximum (MD) and orthogonal diameter (OD) of the wheal. This procedure is time consuming and makes repro-ducible measurements difficult.2,3 Knowing the wheal's area could help make a more accurate diagnosis.4 Over the last 30 years, many attempts have been made to develop a device to measure the size of SPT.3 Nexkin DSPT® (Figure S1A,B) is a novel mechatronic system based on 3D laser technology, that automatically locates allergen's wheal and measures its size (MD, OD and area in square millimeters) (Figure S1C).