The Effect of Frailty on 30-day Mortality Risk in Older Patients With Acute Heart Failure Attended in the Emergency Department

ObjectiveThe objective was to determine the effect of frailty on risk of 30-day mortality in nonseverely disabled older patients with acute heart failure (AHF) attended in emergency departments (EDs). MethodologyThe Frailty-AHF Study is a retrospective analysis of a multicenter, observational, prosp...

Descripción completa

Detalles Bibliográficos
Autores: Martin-Sanchez, FJ, Rodriguez-Adrada, E, Mueller, C, Vidan, MT, Christ, M, Peacock, WF, Rizzi, MA, Alquezar, A, Pinera, P, Aragues, PL, Llorens, P, Herrero, P, Jacob, J, Fernandez, C, Miro, O
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2017
País:España
Institución:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
Repositorio:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
OAI Identifier:oai:iibsantpau.fundanetsuite.com:p6615
Acceso en línea:https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=6615
Access Level:acceso abierto
id ES_5a04af670c063f0580da4e04e0d2a3c2
oai_identifier_str oai:iibsantpau.fundanetsuite.com:p6615
network_acronym_str ES
network_name_str España
repository_id_str
spelling The Effect of Frailty on 30-day Mortality Risk in Older Patients With Acute Heart Failure Attended in the Emergency DepartmentMartin-Sanchez, FJRodriguez-Adrada, EMueller, CVidan, MTChrist, MPeacock, WFRizzi, MAAlquezar, APinera, PAragues, PLLlorens, PHerrero, PJacob, JFernandez, CMiro, OObjectiveThe objective was to determine the effect of frailty on risk of 30-day mortality in nonseverely disabled older patients with acute heart failure (AHF) attended in emergency departments (EDs). MethodologyThe Frailty-AHF Study is a retrospective analysis of a multicenter, observational, prospective, cohort study (Older-AHF Register). This study included consecutive patients 65 years of age without severe functional dependence or dementia attended for AHF in three Spanish EDs for 4 months. Frailty was defined by frailty phenotype as the presence of three or more domains. Baseline and episode characteristics and 30-day mortality were collected in all the patients. ResultsA total of 465 patients with a mean (SD) age of 82 (+/- 7) years were included, 283 (61.0%) being female and 225 (51.3%) with severe comorbidity (Charlson index 3). Frailty was present in 169 (36.3%). The rate of 30-day mortality was 7.3%. Frailty adjusted for potential confounding factors was an independent factor associated with 30-day mortality (adjusted hazard ratio=2.5; 95% confidence interval= 1.0 to 6.0; p=0.047). ConclusionThe presence of frailty is an independent risk factor of 30-day mortality in nonsevere dependent older patients attended with AHF in EDs.WILEY2017info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=6615ACADEMIC EMERGENCY MEDICINEISSN: 10696563ISSNe: 15532712reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pauinstname:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)Inglésinfo:eu-repo/semantics/openAccessoai:iibsantpau.fundanetsuite.com:p66152026-06-14T12:41:47Z
dc.title.none.fl_str_mv The Effect of Frailty on 30-day Mortality Risk in Older Patients With Acute Heart Failure Attended in the Emergency Department
title The Effect of Frailty on 30-day Mortality Risk in Older Patients With Acute Heart Failure Attended in the Emergency Department
spellingShingle The Effect of Frailty on 30-day Mortality Risk in Older Patients With Acute Heart Failure Attended in the Emergency Department
Martin-Sanchez, FJ
title_short The Effect of Frailty on 30-day Mortality Risk in Older Patients With Acute Heart Failure Attended in the Emergency Department
title_full The Effect of Frailty on 30-day Mortality Risk in Older Patients With Acute Heart Failure Attended in the Emergency Department
title_fullStr The Effect of Frailty on 30-day Mortality Risk in Older Patients With Acute Heart Failure Attended in the Emergency Department
title_full_unstemmed The Effect of Frailty on 30-day Mortality Risk in Older Patients With Acute Heart Failure Attended in the Emergency Department
title_sort The Effect of Frailty on 30-day Mortality Risk in Older Patients With Acute Heart Failure Attended in the Emergency Department
dc.creator.none.fl_str_mv Martin-Sanchez, FJ
Rodriguez-Adrada, E
Mueller, C
Vidan, MT
Christ, M
Peacock, WF
Rizzi, MA
Alquezar, A
Pinera, P
Aragues, PL
Llorens, P
Herrero, P
Jacob, J
Fernandez, C
Miro, O
author Martin-Sanchez, FJ
author_facet Martin-Sanchez, FJ
Rodriguez-Adrada, E
Mueller, C
Vidan, MT
Christ, M
Peacock, WF
Rizzi, MA
Alquezar, A
Pinera, P
Aragues, PL
Llorens, P
Herrero, P
Jacob, J
Fernandez, C
Miro, O
author_role author
author2 Rodriguez-Adrada, E
Mueller, C
Vidan, MT
Christ, M
Peacock, WF
Rizzi, MA
Alquezar, A
Pinera, P
Aragues, PL
Llorens, P
Herrero, P
Jacob, J
Fernandez, C
Miro, O
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
description ObjectiveThe objective was to determine the effect of frailty on risk of 30-day mortality in nonseverely disabled older patients with acute heart failure (AHF) attended in emergency departments (EDs). MethodologyThe Frailty-AHF Study is a retrospective analysis of a multicenter, observational, prospective, cohort study (Older-AHF Register). This study included consecutive patients 65 years of age without severe functional dependence or dementia attended for AHF in three Spanish EDs for 4 months. Frailty was defined by frailty phenotype as the presence of three or more domains. Baseline and episode characteristics and 30-day mortality were collected in all the patients. ResultsA total of 465 patients with a mean (SD) age of 82 (+/- 7) years were included, 283 (61.0%) being female and 225 (51.3%) with severe comorbidity (Charlson index 3). Frailty was present in 169 (36.3%). The rate of 30-day mortality was 7.3%. Frailty adjusted for potential confounding factors was an independent factor associated with 30-day mortality (adjusted hazard ratio=2.5; 95% confidence interval= 1.0 to 6.0; p=0.047). ConclusionThe presence of frailty is an independent risk factor of 30-day mortality in nonsevere dependent older patients attended with AHF in EDs.
publishDate 2017
dc.date.none.fl_str_mv 2017
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=6615
url https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=6615
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv WILEY
publisher.none.fl_str_mv WILEY
dc.source.none.fl_str_mv ACADEMIC EMERGENCY MEDICINE
ISSN: 10696563
ISSNe: 15532712
reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
instname_str Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
reponame_str r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
collection r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869408666573078528
score 15,812429

Similares en LA Referencia