Genes involved in the production of antimetabolite toxins by Pseudomonas syringae pathovars

Pseudomonas syringae is pathogenic in a wide variety of plants, causing diseases with economic impacts. Pseudomonas syringae pathovars produce several toxins that can function as virulence factors and contribute to disease symptoms. These virulence factors include antimetabolite toxins, such as tabt...

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Detalhes bibliográficos
Autores: Arrebola, Eva, Cazorla, Francisco Manuel, Pérez-García, Alejandro, Vicente, Antonio de
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2011
País:España
Recursos:Consejo Superior de Investigaciones Científicas (CSIC)
Repositório:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/45136
Acesso em linha:http://hdl.handle.net/10261/45136
Access Level:Acceso aberto
Palavra-chave:secondary metabolite
Gene clusters
tabtoxin
phaseolotoxin
mangotoxin
phytotoxin
Descrição
Resumo:Pseudomonas syringae is pathogenic in a wide variety of plants, causing diseases with economic impacts. Pseudomonas syringae pathovars produce several toxins that can function as virulence factors and contribute to disease symptoms. These virulence factors include antimetabolite toxins, such as tabtoxin, phaseolotoxin and mangotoxin, which target enzymes in the pathways of amino acid metabolism. The antimetabolite toxins are generally located in gene clusters present in the flexible genomes of specific strains. These gene clusters are typically present in blocks of genes that appear to be integrated into specific sites in the P. syringae core genome. A general overview of the genetic organization and biosynthetic and regulatory functions of these genetic traits of the antimetabolite toxins will be given in the present work.