Removal of the chiral inductor from phenylglycinol-derived tricyclic lactams. Unexpected generation of chiral trans-hydrochromene lactones
In the search for synthetic routes for the preparation of cis- and trans- decahydroquinolin-2- ones, a procedure for the generation of enantiopure trans-hydrochromene lactones, by treatment of (R)- phenylglycinol-derived oxazoloquinolone lactams with Na/liq. NH3 followed by acidification, has been d...
| Autores: | , , , , , |
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| Tipo de recurso: | artículo |
| Estado: | Versión aceptada para publicación |
| Fecha de publicación: | 2018 |
| País: | España |
| Institución: | Universidad de Barcelona |
| Repositorio: | Dipòsit Digital de la UB |
| OAI Identifier: | oai:diposit.ub.edu:2445/127602 |
| Acceso en línea: | https://hdl.handle.net/2445/127602 |
| Access Level: | acceso abierto |
| Palabra clave: | Alcaloides Lactames Síntesi asimètrica Alkaloids Lactams Asymmetric synthesis |
| Sumario: | In the search for synthetic routes for the preparation of cis- and trans- decahydroquinolin-2- ones, a procedure for the generation of enantiopure trans-hydrochromene lactones, by treatment of (R)- phenylglycinol-derived oxazoloquinolone lactams with Na/liq. NH3 followed by acidification, has been developed. |
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