One high quality genome and two transcriptome datasets for new species of Mantamonas, a deep-branching eukaryote clade

Mantamonads were long considered to represent an “orphan” lineage in the tree of eukaryotes, likely branching near the most frequently assumed position for the root of eukaryotes. Recent phylogenomic analyses have placed them as part of the “CRuMs” supergroup, along with collodictyonids and rigifili...

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Autores: Blaz, Jazmin, Galindo, Luis Javier, Heiss, Aaron A., Kaur, Harpreet, Torruella, Guifre
Tipo de recurso: artículo
Fecha de publicación:2023
País:España
Institución:Universitat Politècnica de Catalunya (UPC)
Repositorio:UPCommons. Portal del coneixement obert de la UPC
Idioma:inglés
OAI Identifier:oai:upcommons.upc.edu:2117/404020
Acceso en línea:https://hdl.handle.net/2117/404020
https://dx.doi.org/10.1038/s41597-023-02488-2
Access Level:acceso abierto
Palabra clave:Eukaryotic cell genetics
Evolution
Microbiology
Genòmica
Àrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica::Bioinformàtica
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spelling One high quality genome and two transcriptome datasets for new species of Mantamonas, a deep-branching eukaryote cladeBlaz, JazminGalindo, Luis JavierHeiss, Aaron A.Kaur, HarpreetTorruella, GuifreEukaryotic cell geneticsEvolutionMicrobiologyGenòmicaÀrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica::BioinformàticaMantamonads were long considered to represent an “orphan” lineage in the tree of eukaryotes, likely branching near the most frequently assumed position for the root of eukaryotes. Recent phylogenomic analyses have placed them as part of the “CRuMs” supergroup, along with collodictyonids and rigifilids. This supergroup appears to branch at the base of Amorphea, making it of special importance for understanding the deep evolutionary history of eukaryotes. However, the lack of representative species and complete genomic data associated with them has hampered the investigation of their biology and evolution. Here, we isolated and described two new species of mantamonads, Mantamonas vickermani sp. nov. and Mantamonas sphyraenae sp. nov., for each of which we generated transcriptomic sequence data, as well as a high-quality genome for the latter. The estimated size of the M. sphyraenae genome is 25 Mb; our de novo assembly appears to be highly contiguous and complete with 9,416 predicted protein-coding genes. This near-chromosome-scale genome assembly is the first described for the CRuMs supergroup.The authors thank Drs. J.Z. Xiang, D. Xu, and H. Shang at the Weill Cornell’s Genome Resources Core Facility for their assistance with Illumina sequencing. We also thank Dr. S. Goodwin in the NGS sequencing core at Cold Spring Harbor Laboratory for her help with PacBio sequencing, Drs. J.A. Burns and A.A. Pittis for their initial data analysis efforts and K. Lukacs for her help with maintaining the M. sphyraenae cultures. This work was funded by the Simons Foundation Grant awards to EK (SF-382790 & SF-876199). This project has received funding from the European Research Council (ERC) under the European Union’s Horizon 2020 research and innovation programme (ERC Starting Grant No 803151 to L.E., and ERC Advanced Grants No 322669 and 787904 to P.L.-G. and D.M., respectively). L.J.G. was funded by the Horizon 2020 research and innovation programme under the European Marie Skłodowska-Curie Individual Fellowship H2020-MSCA-IF-2020 (grant agreement no. 101022101 - FungEye). GT was supported by the 2019 BP 00208 Beatriu de Pinos-3 Postdoctoral Program (BP3; 801370). Work in the Dacks lab is supported by Discovery Grants from the Natural Sciences and Engineering Research Council of Canada (RES0043758, RES0046091).Peer Reviewed"Article signat per 17 autors/es: Jazmin Blaz, Luis Javier Galindo, Aaron A. Heiss, Harpreet Kaur, Guifré Torruella, Ashley Yang, L. Alexa Thompson, Alexander Filbert, Sally Warring, Apurva Narechania, Takashi Shiratori, Ken-ichiro Ishida, Joel B. Dacks, Purificación López-García, David Moreira, Eunsoo Kim & Laura Eme"Nature Research20232023-01-0120242024-03-08journal articlehttp://purl.org/coar/resource_type/c_6501VoRhttp://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/2117/404020https://dx.doi.org/10.1038/s41597-023-02488-2reponame:UPCommons. Portal del coneixement obert de la UPCinstname:Universitat Politècnica de Catalunya (UPC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Attribution 4.0 Internationalhttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:upcommons.upc.edu:2117/4040202026-05-27T15:37:01Z
dc.title.none.fl_str_mv One high quality genome and two transcriptome datasets for new species of Mantamonas, a deep-branching eukaryote clade
title One high quality genome and two transcriptome datasets for new species of Mantamonas, a deep-branching eukaryote clade
spellingShingle One high quality genome and two transcriptome datasets for new species of Mantamonas, a deep-branching eukaryote clade
Blaz, Jazmin
Eukaryotic cell genetics
Evolution
Microbiology
Genòmica
Àrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica::Bioinformàtica
title_short One high quality genome and two transcriptome datasets for new species of Mantamonas, a deep-branching eukaryote clade
title_full One high quality genome and two transcriptome datasets for new species of Mantamonas, a deep-branching eukaryote clade
title_fullStr One high quality genome and two transcriptome datasets for new species of Mantamonas, a deep-branching eukaryote clade
title_full_unstemmed One high quality genome and two transcriptome datasets for new species of Mantamonas, a deep-branching eukaryote clade
title_sort One high quality genome and two transcriptome datasets for new species of Mantamonas, a deep-branching eukaryote clade
dc.creator.none.fl_str_mv Blaz, Jazmin
Galindo, Luis Javier
Heiss, Aaron A.
Kaur, Harpreet
Torruella, Guifre
author Blaz, Jazmin
author_facet Blaz, Jazmin
Galindo, Luis Javier
Heiss, Aaron A.
Kaur, Harpreet
Torruella, Guifre
author_role author
author2 Galindo, Luis Javier
Heiss, Aaron A.
Kaur, Harpreet
Torruella, Guifre
author2_role author
author
author
author
dc.subject.none.fl_str_mv Eukaryotic cell genetics
Evolution
Microbiology
Genòmica
Àrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica::Bioinformàtica
topic Eukaryotic cell genetics
Evolution
Microbiology
Genòmica
Àrees temàtiques de la UPC::Informàtica::Aplicacions de la informàtica::Bioinformàtica
description Mantamonads were long considered to represent an “orphan” lineage in the tree of eukaryotes, likely branching near the most frequently assumed position for the root of eukaryotes. Recent phylogenomic analyses have placed them as part of the “CRuMs” supergroup, along with collodictyonids and rigifilids. This supergroup appears to branch at the base of Amorphea, making it of special importance for understanding the deep evolutionary history of eukaryotes. However, the lack of representative species and complete genomic data associated with them has hampered the investigation of their biology and evolution. Here, we isolated and described two new species of mantamonads, Mantamonas vickermani sp. nov. and Mantamonas sphyraenae sp. nov., for each of which we generated transcriptomic sequence data, as well as a high-quality genome for the latter. The estimated size of the M. sphyraenae genome is 25 Mb; our de novo assembly appears to be highly contiguous and complete with 9,416 predicted protein-coding genes. This near-chromosome-scale genome assembly is the first described for the CRuMs supergroup.
publishDate 2023
dc.date.none.fl_str_mv 2023
2023-01-01
2024
2024-03-08
dc.type.none.fl_str_mv journal article
http://purl.org/coar/resource_type/c_6501
VoR
http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/2117/404020
https://dx.doi.org/10.1038/s41597-023-02488-2
url https://hdl.handle.net/2117/404020
https://dx.doi.org/10.1038/s41597-023-02488-2
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Attribution 4.0 International
http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Nature Research
publisher.none.fl_str_mv Nature Research
dc.source.none.fl_str_mv reponame:UPCommons. Portal del coneixement obert de la UPC
instname:Universitat Politècnica de Catalunya (UPC)
instname_str Universitat Politècnica de Catalunya (UPC)
reponame_str UPCommons. Portal del coneixement obert de la UPC
collection UPCommons. Portal del coneixement obert de la UPC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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