Prediction of cardiovascular disease by the framingham-REGICOR equation in the high-risk PREDIMED cohort: Impact of the mediterranean diet across different risk strata

Amor, A.J.; Serra-Mir, M.; Martínez-González, M.A.; Corella, D.; Salas-Salvadó, J.; Fitó, Montserrat; Estruch, R.; Serra-Majem, L.; Arós, F.; Babio, Nancy; Ros, E.; Cofán, M.; Lecea, O.; Rosique Esteban, N.; Valls-Pedret, C.; Freitas-Simoes, T.M.; Doménech, M.; Gilabert, R.; Sagredo Arce, T.; Bertolín-Muñoz, A.; Tresserra-Rimbau, A.; Jurado-Ruíz, Enrique; Salaverría, I.; Pages, M.A.; Cabré, J.J.; Mestres, G.; Paris, F.; Llauradó, M.; Pedret, R.; Basells, J.; Vizcaino, J.; Segarra, R.; Sacanella, E.; Casas, Ricard; Frontera, G.; Alonso-Gómez, A.; Godoy, D.; López-Sabater, M.C.; de la Torre, Rafael; del Hierro, T.; Hernandez-Alonso, P.; Giardina, S.; Ferreira-Pego, C.; Pérez-Cabrera, J.; Papandreou, C.; Baby, P.; Camacho, L.; Toledo, E.; Casanas Quintana, T.; Carratalá-Calvo, A.; Buil-Cosiales, P.; Rovira, A.; Ruiz-Canela, M.; Martínez, J. Alfredo; Fiol, Miquel; Castellote-Bargalló, Ana I.; Algorta, J.; Álvarez-Pérez, J.; Sanjulián, B.; Ortega, E.; Sánchez-Tainta, A.; Díez-Espino, Javier; Sánchez-Villegas, A.; Ginard, M.; Fiol, F.; García-Valdueza, M.; Marrugat, J.; Schröder, H.; Molina, N.; Maestre, E.; Castañer, O.; Farré, M.; Sorli, J.V.; Ramos, A.; García, J.; Moñino, M.; Santamaría, M.I.; Fernández-Rodríguez, M. J.; Jover, A.; Pérez-Heras, A.; Zanon-Moreno, V.; Díaz-Benítez, E.M.; Carrasco, P.; Ortega-Azorín, Carolina; Asensio, E.M.; Oller, M.; Proenza, A.; Osma, R.; Bargalló, Núria; Barragán, Rocío; Francés, F.; García, M.; Romaguera, D.; Guillén, M.; Márquez, F.; González, J.I.; Saiz, C.; Portillo, María P.; Mengual, L.; Viñas, C.; Bautista-Castaño, Inmaculada; de Santamaría, L.; Portolés, Olga; Giménez, F.J.; Coltell, O.; Guillem-Saiz, P.; Chiva, G.; Mata, M.; Sorli, M.; de Juan, C.; Roura, P.; Rekondo, J.; Belló, M.C.; Loma-Osorio, A.; Gómez-Gracia, Enrique; Warnberg, J.; Benítez Pont, R.; Bianchi Alba, M.; Gómez-Huelgas, R.; Gueto Rubio, M.V.; Bulló, M.; Sáez, G.; Yuste, M.C.; Martínez, P.; Valderas, P.; Brau, A.; Martínez-González, J.; Velasco García, V.; Romero, S.; de Diego Salas, J.; Razquin, C.; Baca Osorio, A.; Gil Zarzosa, J.; Becerra-Tomás, Nerea; Guarner, A.; Sánchez Luque, J.J.; Eguaras, S.; Vargas López, E.; Ruiz-Gutiérrez, Valentina; Ibarrola-Jurado, Nuria; Tur, Josep A.; García Roselló, J.; Perona, Javier S.; Vigata López, M.D.; Montero Romero, Emilio; García-García, M.; Isach, A.; Basora, J.; González, R.; Nissensohn, M.; Díaz-González, V.; Ruano-Rodríguez, C.; Ortiz-Andrelluchi, A.P.; Macías Gutiérrez, B.; Santana-Santana, A.J.; Pintó, Xavier; de la Cruz, E.; García-Arellano, A.; Mena, G.; Marti, A.; Salas-Huetos, A.; Díaz-López, A.; Arceiz Campo, M.T.; Arranz, S.; Martín, F.; Galera, A.; Soler, Y.; Trias, F.; Elosua, R.; Sarasa, I.; Quiles, L.; Padres, E.; Corbella, Emili; Muñoz-Aguayo, Daniel; Molina, C.; Cabezas, C.; Martín-Rillo, M.J.; Vinyoles, E.; Rovira, M.A.; Goñi, E.; Urtasun Samper, A.; Tort, N.; Sola, A.; García, L.; Baena, J.M.; Flores, G.; Verdú, J.M.; Tello, S.; Arroyo-Azpa, C.; García-Pérez, L.; Vazquez, Z.; Amat, J.; Duaso, I.; García, Y.; Iglesias, C.; Simón, C.; Quinzavos, L.; Parra, L.; Liroz, M.; Pascual, V.; García de la Noceda Montoy, M.D.; Berrade, N.; Llopis-Osorio, E.; Vila, J.; Villanueva Telleria, J.; Benavent, J.; Clos, J.; Pla, I.; Amorós, M.; Bonet, M.T.; Sanz, E.; Extremera-Urabayen, V.; Martin Monzón, Maria Teresa; Prieto, R.; Sánchez, M.S.; Altirriba, J.; Ruiz-Baixauli, J.; Cortés Ugalde, F.; Manzano, E.; Lamuela-Raventós, Rosa M.; Altés, A.; Sala-Vila, A.; Francisco, S.; Riera, C.

Prediction of cardiovascular disease by the framingham-REGICOR equation in the high-risk PREDIMED cohort: Impact of the mediterranean diet across different risk strata

Background-The usefulness of cardiovascular disease (CVD) predictive equations in different populations is debatable. We assessed the efficacy of the Framingham-REGICOR scale, validated for the Spanish population, to identify future CVD in participants, who were predefined as being at high-risk in t...

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Autores:	Amor, A.J., Serra-Mir, M., Martínez-González, M.A., Corella, D., Salas-Salvadó, J., Fitó, Montserrat, Estruch, R., Serra-Majem, L., Arós, F., Babio, Nancy, Ros, E., Cofán, M., Lecea, O., Rosique Esteban, N., Valls-Pedret, C., Freitas-Simoes, T.M., Doménech, M., Gilabert, R., Sagredo Arce, T., Bertolín-Muñoz, A., Tresserra-Rimbau, A., Jurado-Ruíz, Enrique, Salaverría, I., Pages, M.A., Cabré, J.J., Mestres, G., Paris, F., Llauradó, M., Pedret, R., Basells, J., Vizcaino, J., Segarra, R., Sacanella, E., Casas, Ricard, Frontera, G., Alonso-Gómez, A., Godoy, D., López-Sabater, M.C., de la Torre, Rafael, del Hierro, T., Hernandez-Alonso, P., Giardina, S., Ferreira-Pego, C., Pérez-Cabrera, J., Papandreou, C., Baby, P., Camacho, L., Toledo, E., Casanas Quintana, T., Carratalá-Calvo, A., Buil-Cosiales, P., Rovira, A., Ruiz-Canela, M., Martínez, J. Alfredo, Fiol, Miquel, Castellote-Bargalló, Ana I., Algorta, J., Álvarez-Pérez, J., Sanjulián, B., Ortega, E., Sánchez-Tainta, A., Díez-Espino, Javier, Sánchez-Villegas, A., Ginard, M., Fiol, F., García-Valdueza, M., Marrugat, J., Schröder, H., Molina, N., Maestre, E., Castañer, O., Farré, M., Sorli, J.V., Ramos, A., García, J., Moñino, M., Santamaría, M.I., Fernández-Rodríguez, M. J., Jover, A., Pérez-Heras, A., Zanon-Moreno, V., Díaz-Benítez, E.M., Carrasco, P., Ortega-Azorín, Carolina, Asensio, E.M., Oller, M., Proenza, A., Osma, R., Bargalló, Núria, Barragán, Rocío, Francés, F., García, M., Romaguera, D., Guillén, M., Márquez, F., González, J.I., Saiz, C., Portillo, María P., Mengual, L., Viñas, C., Bautista-Castaño, Inmaculada, de Santamaría, L., Portolés, Olga, Giménez, F.J., Coltell, O., Guillem-Saiz, P., Chiva, G., Mata, M., Sorli, M., de Juan, C., Roura, P., Rekondo, J., Belló, M.C., Loma-Osorio, A., Gómez-Gracia, Enrique, Warnberg, J., Benítez Pont, R., Bianchi Alba, M., Gómez-Huelgas, R., Gueto Rubio, M.V., Bulló, M., Sáez, G., Yuste, M.C., Martínez, P., Valderas, P., Brau, A., Martínez-González, J., Velasco García, V., Romero, S., de Diego Salas, J., Razquin, C., Baca Osorio, A., Gil Zarzosa, J., Becerra-Tomás, Nerea, Guarner, A., Sánchez Luque, J.J., Eguaras, S., Vargas López, E., Ruiz-Gutiérrez, Valentina, Ibarrola-Jurado, Nuria, Tur, Josep A., García Roselló, J., Perona, Javier S., Vigata López, M.D., Montero Romero, Emilio, García-García, M., Isach, A., Basora, J., González, R., Nissensohn, M., Díaz-González, V., Ruano-Rodríguez, C., Ortiz-Andrelluchi, A.P., Macías Gutiérrez, B., Santana-Santana, A.J., Pintó, Xavier, de la Cruz, E., García-Arellano, A., Mena, G., Marti, A., Salas-Huetos, A., Díaz-López, A., Arceiz Campo, M.T., Arranz, S., Martín, F., Galera, A., Soler, Y., Trias, F., Elosua, R., Sarasa, I., Quiles, L., Padres, E., Corbella, Emili, Muñoz-Aguayo, Daniel, Molina, C., Cabezas, C., Martín-Rillo, M.J., Vinyoles, E., Rovira, M.A., Goñi, E., Urtasun Samper, A., Tort, N., Sola, A., García, L., Baena, J.M., Flores, G., Verdú, J.M., Tello, S., Arroyo-Azpa, C., García-Pérez, L., Vazquez, Z., Amat, J., Duaso, I., García, Y., Iglesias, C., Simón, C., Quinzavos, L., Parra, L., Liroz, M., Pascual, V., García de la Noceda Montoy, M.D., Berrade, N., Llopis-Osorio, E., Vila, J., Villanueva Telleria, J., Benavent, J., Clos, J., Pla, I., Amorós, M., Bonet, M.T., Sanz, E., Extremera-Urabayen, V., Martin Monzón, Maria Teresa, Prieto, R., Sánchez, M.S., Altirriba, J., Ruiz-Baixauli, J., Cortés Ugalde, F., Manzano, E., Lamuela-Raventós, Rosa M., Altés, A., Sala-Vila, A., Francisco, S., Riera, C.
Tipo de recurso:	artículo
Estado:	Versión publicada
Fecha de publicación:	2017
País:	España
Institución:	Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:	DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:	oai:digital.csic.es:10261/166179
Acceso en línea:	http://hdl.handle.net/10261/166179
Access Level:	acceso abierto
Palabra clave:	PREDIMED Framingham-REGICOR equation Cardiovascular risk prediction Cardiovascular disease Mediterraneam diet

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oai_identifier_str	oai:digital.csic.es:10261/166179
network_acronym_str	ES
network_name_str	España
repository_id_str
dc.title.none.fl_str_mv	Prediction of cardiovascular disease by the framingham-REGICOR equation in the high-risk PREDIMED cohort: Impact of the mediterranean diet across different risk strata
title	Prediction of cardiovascular disease by the framingham-REGICOR equation in the high-risk PREDIMED cohort: Impact of the mediterranean diet across different risk strata
spellingShingle	Prediction of cardiovascular disease by the framingham-REGICOR equation in the high-risk PREDIMED cohort: Impact of the mediterranean diet across different risk strata Amor, A.J. PREDIMED Framingham-REGICOR equation Cardiovascular risk prediction Cardiovascular disease Mediterraneam diet
title_short	Prediction of cardiovascular disease by the framingham-REGICOR equation in the high-risk PREDIMED cohort: Impact of the mediterranean diet across different risk strata
title_full	Prediction of cardiovascular disease by the framingham-REGICOR equation in the high-risk PREDIMED cohort: Impact of the mediterranean diet across different risk strata
title_fullStr	Prediction of cardiovascular disease by the framingham-REGICOR equation in the high-risk PREDIMED cohort: Impact of the mediterranean diet across different risk strata
title_full_unstemmed	Prediction of cardiovascular disease by the framingham-REGICOR equation in the high-risk PREDIMED cohort: Impact of the mediterranean diet across different risk strata
title_sort	Prediction of cardiovascular disease by the framingham-REGICOR equation in the high-risk PREDIMED cohort: Impact of the mediterranean diet across different risk strata
dc.creator.none.fl_str_mv	Amor, A.J. Serra-Mir, M. Martínez-González, M.A. Corella, D. Salas-Salvadó, J. Fitó, Montserrat Estruch, R. Serra-Majem, L. Arós, F. Babio, Nancy Ros, E. Cofán, M. Lecea, O. Rosique Esteban, N. Valls-Pedret, C. Freitas-Simoes, T.M. Doménech, M. Gilabert, R. Sagredo Arce, T. Bertolín-Muñoz, A. Tresserra-Rimbau, A. Jurado-Ruíz, Enrique Salaverría, I. Pages, M.A. Cabré, J.J. Mestres, G. Paris, F. Llauradó, M. Pedret, R. Basells, J. Vizcaino, J. Segarra, R. Sacanella, E. Casas, Ricard Frontera, G. Alonso-Gómez, A. Godoy, D. López-Sabater, M.C. de la Torre, Rafael del Hierro, T. Hernandez-Alonso, P. Giardina, S. Ferreira-Pego, C. Pérez-Cabrera, J. Papandreou, C. Baby, P. Camacho, L. Toledo, E. Casanas Quintana, T. Carratalá-Calvo, A. Buil-Cosiales, P. Rovira, A. Ruiz-Canela, M. Martínez, J. Alfredo Fiol, Miquel Castellote-Bargalló, Ana I. Algorta, J. Álvarez-Pérez, J. Sanjulián, B. Ortega, E. Sánchez-Tainta, A. Díez-Espino, Javier Sánchez-Villegas, A. Ginard, M. Fiol, F. García-Valdueza, M. Marrugat, J. Schröder, H. Molina, N. Maestre, E. Castañer, O. Rovira, A. Farré, M. Sorli, J.V. Ramos, A. García, J. Moñino, M. Santamaría, M.I. Fernández-Rodríguez, M. J. Jover, A. Pérez-Heras, A. Zanon-Moreno, V. Díaz-Benítez, E.M. Carrasco, P. Ortega-Azorín, Carolina Asensio, E.M. Oller, M. Proenza, A. Osma, R. Bargalló, Núria Barragán, Rocío Francés, F. García, M. Romaguera, D. Guillén, M. Márquez, F. González, J.I. Saiz, C. Portillo, María P. Mengual, L. Viñas, C. Bautista-Castaño, Inmaculada de Santamaría, L. Portolés, Olga Giménez, F.J. Coltell, O. Guillem-Saiz, P. Chiva, G. Mata, M. Sorli, M. de Juan, C. Roura, P. Rekondo, J. Belló, M.C. Loma-Osorio, A. Gómez-Gracia, Enrique Warnberg, J. Benítez Pont, R. Bianchi Alba, M. Gómez-Huelgas, R. Gueto Rubio, M.V. Bulló, M. Sáez, G. Yuste, M.C. Martínez, P. Valderas, P. Brau, A. Martínez-González, J. Velasco García, V. Romero, S. de Diego Salas, J. Razquin, C. Baca Osorio, A. Gil Zarzosa, J. Becerra-Tomás, Nerea Guarner, A. Sánchez Luque, J.J. Eguaras, S. Vargas López, E. Ruiz-Gutiérrez, Valentina Ibarrola-Jurado, Nuria Tur, Josep A. García Roselló, J. Perona, Javier S. Vigata López, M.D. Montero Romero, Emilio García-García, M. Isach, A. Basora, J. González, R. Nissensohn, M. Díaz-González, V. Ruano-Rodríguez, C. Ortiz-Andrelluchi, A.P. Macías Gutiérrez, B. Santana-Santana, A.J. Pintó, Xavier de la Cruz, E. García-Arellano, A. Mena, G. Marti, A. Salas-Huetos, A. Díaz-López, A. Arceiz Campo, M.T. Arranz, S. Martín, F. Galera, A. Soler, Y. Trias, F. Elosua, R. Sarasa, I. Quiles, L. Padres, E. Corbella, Emili Muñoz-Aguayo, Daniel Molina, C. Cabezas, C. Martín-Rillo, M.J. Vinyoles, E. Rovira, M.A. Goñi, E. Urtasun Samper, A. Tort, N. Sola, A. García, L. Baena, J.M. Flores, G. Verdú, J.M. Tello, S. Arroyo-Azpa, C. García-Pérez, L. Vazquez, Z. Amat, J. Duaso, I. García, Y. Iglesias, C. Simón, C. Quinzavos, L. Parra, L. Liroz, M. Pascual, V. García de la Noceda Montoy, M.D. Berrade, N. Llopis-Osorio, E. Vila, J. Villanueva Telleria, J. Benavent, J. Clos, J. Goñi, E. Pla, I. Amorós, M. Bonet, M.T. Sanz, E. Extremera-Urabayen, V. Martin Monzón, Maria Teresa Prieto, R. Sánchez, M.S. Altirriba, J. Ruiz-Baixauli, J. Cortés Ugalde, F. Manzano, E. Lamuela-Raventós, Rosa M. Altés, A. Sala-Vila, A. Francisco, S. Riera, C.
author	Amor, A.J.
author_facet	Amor, A.J. Serra-Mir, M. Martínez-González, M.A. Corella, D. Salas-Salvadó, J. Fitó, Montserrat Estruch, R. Serra-Majem, L. Arós, F. Babio, Nancy Ros, E. Cofán, M. Lecea, O. Rosique Esteban, N. Valls-Pedret, C. Freitas-Simoes, T.M. Doménech, M. Gilabert, R. Sagredo Arce, T. Bertolín-Muñoz, A. Tresserra-Rimbau, A. Jurado-Ruíz, Enrique Salaverría, I. Pages, M.A. Cabré, J.J. Mestres, G. Paris, F. Llauradó, M. Pedret, R. Basells, J. Vizcaino, J. Segarra, R. Sacanella, E. Casas, Ricard Frontera, G. Alonso-Gómez, A. Godoy, D. López-Sabater, M.C. de la Torre, Rafael del Hierro, T. Hernandez-Alonso, P. Giardina, S. Ferreira-Pego, C. Pérez-Cabrera, J. Papandreou, C. Baby, P. Camacho, L. Toledo, E. Casanas Quintana, T. Carratalá-Calvo, A. Buil-Cosiales, P. Rovira, A. Ruiz-Canela, M. Martínez, J. Alfredo Fiol, Miquel Castellote-Bargalló, Ana I. Algorta, J. Álvarez-Pérez, J. Sanjulián, B. Ortega, E. Sánchez-Tainta, A. Díez-Espino, Javier Sánchez-Villegas, A. Ginard, M. Fiol, F. García-Valdueza, M. Marrugat, J. Schröder, H. Molina, N. Maestre, E. Castañer, O. Farré, M. Sorli, J.V. Ramos, A. García, J. Moñino, M. Santamaría, M.I. Fernández-Rodríguez, M. J. Jover, A. Pérez-Heras, A. Zanon-Moreno, V. Díaz-Benítez, E.M. Carrasco, P. Ortega-Azorín, Carolina Asensio, E.M. Oller, M. Proenza, A. Osma, R. Bargalló, Núria Barragán, Rocío Francés, F. García, M. Romaguera, D. Guillén, M. Márquez, F. González, J.I. Saiz, C. Portillo, María P. Mengual, L. Viñas, C. Bautista-Castaño, Inmaculada de Santamaría, L. Portolés, Olga Giménez, F.J. Coltell, O. Guillem-Saiz, P. Chiva, G. Mata, M. Sorli, M. de Juan, C. Roura, P. Rekondo, J. Belló, M.C. Loma-Osorio, A. Gómez-Gracia, Enrique Warnberg, J. Benítez Pont, R. Bianchi Alba, M. Gómez-Huelgas, R. Gueto Rubio, M.V. Bulló, M. Sáez, G. Yuste, M.C. Martínez, P. Valderas, P. Brau, A. Martínez-González, J. Velasco García, V. Romero, S. de Diego Salas, J. Razquin, C. Baca Osorio, A. Gil Zarzosa, J. Becerra-Tomás, Nerea Guarner, A. Sánchez Luque, J.J. Eguaras, S. Vargas López, E. Ruiz-Gutiérrez, Valentina Ibarrola-Jurado, Nuria Tur, Josep A. García Roselló, J. Perona, Javier S. Vigata López, M.D. Montero Romero, Emilio García-García, M. Isach, A. Basora, J. González, R. Nissensohn, M. Díaz-González, V. Ruano-Rodríguez, C. Ortiz-Andrelluchi, A.P. Macías Gutiérrez, B. Santana-Santana, A.J. Pintó, Xavier de la Cruz, E. García-Arellano, A. Mena, G. Marti, A. Salas-Huetos, A. Díaz-López, A. Arceiz Campo, M.T. Arranz, S. Martín, F. Galera, A. Soler, Y. Trias, F. Elosua, R. Sarasa, I. Quiles, L. Padres, E. Corbella, Emili Muñoz-Aguayo, Daniel Molina, C. Cabezas, C. Martín-Rillo, M.J. Vinyoles, E. Rovira, M.A. Goñi, E. Urtasun Samper, A. Tort, N. Sola, A. García, L. Baena, J.M. Flores, G. Verdú, J.M. Tello, S. Arroyo-Azpa, C. García-Pérez, L. Vazquez, Z. Amat, J. Duaso, I. García, Y. Iglesias, C. Simón, C. Quinzavos, L. Parra, L. Liroz, M. Pascual, V. García de la Noceda Montoy, M.D. Berrade, N. Llopis-Osorio, E. Vila, J. Villanueva Telleria, J. Benavent, J. Clos, J. Pla, I. Amorós, M. Bonet, M.T. Sanz, E. Extremera-Urabayen, V. Martin Monzón, Maria Teresa Prieto, R. Sánchez, M.S. Altirriba, J. Ruiz-Baixauli, J. Cortés Ugalde, F. Manzano, E. Lamuela-Raventós, Rosa M. Altés, A. Sala-Vila, A. Francisco, S. Riera, C.
author_role	author
author2	Serra-Mir, M. Martínez-González, M.A. Corella, D. Salas-Salvadó, J. Fitó, Montserrat Estruch, R. Serra-Majem, L. Arós, F. Babio, Nancy Ros, E. Cofán, M. Lecea, O. Rosique Esteban, N. Valls-Pedret, C. Freitas-Simoes, T.M. Doménech, M. Gilabert, R. Sagredo Arce, T. Bertolín-Muñoz, A. Tresserra-Rimbau, A. Jurado-Ruíz, Enrique Salaverría, I. Pages, M.A. Cabré, J.J. Mestres, G. Paris, F. Llauradó, M. Pedret, R. Basells, J. Vizcaino, J. Segarra, R. Sacanella, E. Casas, Ricard Frontera, G. Alonso-Gómez, A. Godoy, D. López-Sabater, M.C. de la Torre, Rafael del Hierro, T. Hernandez-Alonso, P. Giardina, S. Ferreira-Pego, C. Pérez-Cabrera, J. Papandreou, C. Baby, P. Camacho, L. Toledo, E. Casanas Quintana, T. Carratalá-Calvo, A. Buil-Cosiales, P. Rovira, A. Ruiz-Canela, M. Martínez, J. Alfredo Fiol, Miquel Castellote-Bargalló, Ana I. Algorta, J. Álvarez-Pérez, J. Sanjulián, B. Ortega, E. Sánchez-Tainta, A. Díez-Espino, Javier Sánchez-Villegas, A. Ginard, M. Fiol, F. García-Valdueza, M. Marrugat, J. Schröder, H. Molina, N. Maestre, E. Castañer, O. Farré, M. Sorli, J.V. Ramos, A. García, J. Moñino, M. Santamaría, M.I. Fernández-Rodríguez, M. J. Jover, A. Pérez-Heras, A. Zanon-Moreno, V. Díaz-Benítez, E.M. Carrasco, P. Ortega-Azorín, Carolina Asensio, E.M. Oller, M. Proenza, A. Osma, R. Bargalló, Núria Barragán, Rocío Francés, F. García, M. Romaguera, D. Guillén, M. Márquez, F. González, J.I. Saiz, C. Portillo, María P. Mengual, L. Viñas, C. Bautista-Castaño, Inmaculada de Santamaría, L. Portolés, Olga Giménez, F.J. Coltell, O. Guillem-Saiz, P. Chiva, G. Mata, M. Sorli, M. de Juan, C. Roura, P. Rekondo, J. Belló, M.C. Loma-Osorio, A. Gómez-Gracia, Enrique Warnberg, J. Benítez Pont, R. Bianchi Alba, M. Gómez-Huelgas, R. Gueto Rubio, M.V. Bulló, M. Sáez, G. Yuste, M.C. Martínez, P. Valderas, P. Brau, A. Martínez-González, J. Velasco García, V. Romero, S. de Diego Salas, J. Razquin, C. Baca Osorio, A. Gil Zarzosa, J. Becerra-Tomás, Nerea Guarner, A. Sánchez Luque, J.J. Eguaras, S. Vargas López, E. Ruiz-Gutiérrez, Valentina Ibarrola-Jurado, Nuria Tur, Josep A. García Roselló, J. Perona, Javier S. Vigata López, M.D. Montero Romero, Emilio García-García, M. Isach, A. Basora, J. González, R. Nissensohn, M. Díaz-González, V. Ruano-Rodríguez, C. Ortiz-Andrelluchi, A.P. Macías Gutiérrez, B. Santana-Santana, A.J. Pintó, Xavier de la Cruz, E. García-Arellano, A. Mena, G. Marti, A. Salas-Huetos, A. Díaz-López, A. Arceiz Campo, M.T. Arranz, S. Martín, F. Galera, A. Soler, Y. Trias, F. Elosua, R. Sarasa, I. Quiles, L. Padres, E. Corbella, Emili Muñoz-Aguayo, Daniel Molina, C. Cabezas, C. Martín-Rillo, M.J. Vinyoles, E. Rovira, M.A. Goñi, E. Urtasun Samper, A. Tort, N. Sola, A. García, L. Baena, J.M. Flores, G. Verdú, J.M. Tello, S. Arroyo-Azpa, C. García-Pérez, L. Vazquez, Z. Amat, J. Duaso, I. García, Y. Iglesias, C. Simón, C. Quinzavos, L. Parra, L. Liroz, M. Pascual, V. García de la Noceda Montoy, M.D. Berrade, N. Llopis-Osorio, E. Vila, J. Villanueva Telleria, J. Benavent, J. Clos, J. Pla, I. Amorós, M. Bonet, M.T. Sanz, E. Extremera-Urabayen, V. Martin Monzón, Maria Teresa Prieto, R. Sánchez, M.S. Altirriba, J. Ruiz-Baixauli, J. Cortés Ugalde, F. Manzano, E. Lamuela-Raventós, Rosa M. Altés, A. Sala-Vila, A. Francisco, S. Riera, C.
author2_role	author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author
dc.contributor.none.fl_str_mv	Instituto de Salud Carlos III Centro Nacional de Investigaciones Cardiovasculares (España) Ministerio de Ciencia e Innovación (España) California Walnut Commission Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv	PREDIMED Framingham-REGICOR equation Cardiovascular risk prediction Cardiovascular disease Mediterraneam diet
topic	PREDIMED Framingham-REGICOR equation Cardiovascular risk prediction Cardiovascular disease Mediterraneam diet
description	Background-The usefulness of cardiovascular disease (CVD) predictive equations in different populations is debatable. We assessed the efficacy of the Framingham-REGICOR scale, validated for the Spanish population, to identify future CVD in participants, who were predefined as being at high-risk in the PREvención con DIeta MEDiterránea (PREDIMED) study-a nutrition-intervention primary prevention trial-and the impact of adherence to the Mediterranean diet on CVD across risk categories. Methods and Results-In a post hoc analysis, we assessed the CVD predictive value of baseline estimated risk in 5966 PREDIMED participants (aged 55-74 years, 57% women; 48% with type 2 diabetes mellitus). Major CVD events, the primary PREDIMED end point, were an aggregate of myocardial infarction, stroke, and cardiovascular death. Multivariate-adjusted Cox regression was used to calculate hazard ratios for major CVD events and effect modification from the Mediterranean diet intervention across risk strata (low, moderate, high, very high). The Framingham-REGICOR classification of PREDIMED participants was 25.1% low risk, 44.5% moderate risk, and 30.4% high or very high risk. During 6-year follow-up, 188 major CVD events occurred. Hazard ratios for major CVD events increased in parallel with estimated risk (2.68, 4.24, and 6.60 for moderate, high, and very high risk), particularly in men (7.60, 13.16, and 15.85, respectively, versus 2.16, 2.28, and 3.51, respectively, in women). Yet among those with low or moderate risk, 32.2% and 74.3% of major CVD events occurred in men and women, respectively. Mediterranean diet adherence was associated with CVD risk reduction regardless of risk strata (P > 0.4 for interaction). Conclusions-Incident CVD increased in parallel with estimated risk in the PREDIMED cohort, but most events occurred in non- high-risk categories, particularly in women. Until predictive tools are improved, promotion of the Mediterranean diet might be useful to reduce CVD independent of baseline risk.
publishDate	2017
dc.date.none.fl_str_mv	2017 2018 2018 2018
dc.type.none.fl_str_mv	info:eu-repo/semantics/article http://purl.org/coar/resource_type/c_6501 Publisher's version info:eu-repo/semantics/publishedVersion
format	article
status_str	publishedVersion
dc.identifier.none.fl_str_mv	http://hdl.handle.net/10261/166179
url	http://hdl.handle.net/10261/166179
dc.language.none.fl_str_mv	Inglés
language_invalid_str_mv	Inglés
dc.relation.none.fl_str_mv	#PLACEHOLDER_PARENT_METADATA_VALUE# info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2010‐22319‐C03‐02 ; Sí
dc.rights.none.fl_str_mv	info:eu-repo/semantics/openAccess
eu_rights_str_mv	openAccess
dc.publisher.none.fl_str_mv	John Wiley & Sons
publisher.none.fl_str_mv	John Wiley & Sons
dc.source.none.fl_str_mv	reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str	Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str	DIGITAL.CSIC. Repositorio Institucional del CSIC
collection	DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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spelling	Prediction of cardiovascular disease by the framingham-REGICOR equation in the high-risk PREDIMED cohort: Impact of the mediterranean diet across different risk strataAmor, A.J.Serra-Mir, M.Martínez-González, M.A.Corella, D.Salas-Salvadó, J.Fitó, MontserratEstruch, R.Serra-Majem, L.Arós, F.Babio, NancyRos, E.Cofán, M.Lecea, O.Rosique Esteban, N.Valls-Pedret, C.Freitas-Simoes, T.M.Doménech, M.Gilabert, R.Sagredo Arce, T.Bertolín-Muñoz, A.Tresserra-Rimbau, A.Jurado-Ruíz, EnriqueSalaverría, I.Pages, M.A.Cabré, J.J.Mestres, G.Paris, F.Llauradó, M.Pedret, R.Basells, J.Vizcaino, J.Segarra, R.Sacanella, E.Casas, RicardFrontera, G.Alonso-Gómez, A.Godoy, D.López-Sabater, M.C.de la Torre, Rafaeldel Hierro, T.Hernandez-Alonso, P.Giardina, S.Ferreira-Pego, C.Pérez-Cabrera, J.Papandreou, C.Baby, P.Camacho, L.Toledo, E.Casanas Quintana, T.Carratalá-Calvo, A.Buil-Cosiales, P.Rovira, A.Ruiz-Canela, M.Martínez, J. AlfredoFiol, MiquelCastellote-Bargalló, Ana I.Algorta, J.Álvarez-Pérez, J.Sanjulián, B.Ortega, E.Sánchez-Tainta, A.Díez-Espino, JavierSánchez-Villegas, A.Ginard, M.Fiol, F.García-Valdueza, M.Marrugat, J.Schröder, H.Molina, N.Maestre, E.Castañer, O.Rovira, A.Farré, M.Sorli, J.V.Ramos, A.García, J.Moñino, M.Santamaría, M.I.Fernández-Rodríguez, M. J.Jover, A.Pérez-Heras, A.Zanon-Moreno, V.Díaz-Benítez, E.M.Carrasco, P.Ortega-Azorín, CarolinaAsensio, E.M.Oller, M.Proenza, A.Osma, R.Bargalló, NúriaBarragán, RocíoFrancés, F.García, M.Romaguera, D.Guillén, M.Márquez, F.González, J.I.Saiz, C.Portillo, María P.Mengual, L.Viñas, C.Bautista-Castaño, Inmaculadade Santamaría, L.Portolés, OlgaGiménez, F.J.Coltell, O.Guillem-Saiz, P.Chiva, G.Mata, M.Sorli, M.de Juan, C.Roura, P.Rekondo, J.Belló, M.C.Loma-Osorio, A.Gómez-Gracia, EnriqueWarnberg, J.Benítez Pont, R.Bianchi Alba, M.Gómez-Huelgas, R.Gueto Rubio, M.V.Bulló, M.Sáez, G.Yuste, M.C.Martínez, P.Valderas, P.Brau, A.Martínez-González, J.Velasco García, V.Romero, S.de Diego Salas, J.Razquin, C.Baca Osorio, A.Gil Zarzosa, J.Becerra-Tomás, NereaGuarner, A.Sánchez Luque, J.J.Eguaras, S.Vargas López, E.Ruiz-Gutiérrez, ValentinaIbarrola-Jurado, NuriaTur, Josep A.García Roselló, J.Perona, Javier S.Vigata López, M.D.Montero Romero, EmilioGarcía-García, M.Isach, A.Basora, J.González, R.Nissensohn, M.Díaz-González, V.Ruano-Rodríguez, C.Ortiz-Andrelluchi, A.P.Macías Gutiérrez, B.Santana-Santana, A.J.Pintó, Xavierde la Cruz, E.García-Arellano, A.Mena, G.Marti, A.Salas-Huetos, A.Díaz-López, A.Arceiz Campo, M.T.Arranz, S.Martín, F.Galera, A.Soler, Y.Trias, F.Elosua, R.Sarasa, I.Quiles, L.Padres, E.Corbella, EmiliMuñoz-Aguayo, DanielMolina, C.Cabezas, C.Martín-Rillo, M.J.Vinyoles, E.Rovira, M.A.Goñi, E.Urtasun Samper, A.Tort, N.Sola, A.García, L.Baena, J.M.Flores, G.Verdú, J.M.Tello, S.Arroyo-Azpa, C.García-Pérez, L.Vazquez, Z.Amat, J.Duaso, I.García, Y.Iglesias, C.Simón, C.Quinzavos, L.Parra, L.Liroz, M.Pascual, V.García de la Noceda Montoy, M.D.Berrade, N.Llopis-Osorio, E.Vila, J.Villanueva Telleria, J.Benavent, J.Clos, J.Goñi, E.Pla, I.Amorós, M.Bonet, M.T.Sanz, E.Extremera-Urabayen, V.Martin Monzón, Maria TeresaPrieto, R.Sánchez, M.S.Altirriba, J.Ruiz-Baixauli, J.Cortés Ugalde, F.Manzano, E.Lamuela-Raventós, Rosa M.Altés, A.Sala-Vila, A.Francisco, S.Riera, C.PREDIMEDFramingham-REGICOR equationCardiovascular risk predictionCardiovascular diseaseMediterraneam dietBackground-The usefulness of cardiovascular disease (CVD) predictive equations in different populations is debatable. We assessed the efficacy of the Framingham-REGICOR scale, validated for the Spanish population, to identify future CVD in participants, who were predefined as being at high-risk in the PREvención con DIeta MEDiterránea (PREDIMED) study-a nutrition-intervention primary prevention trial-and the impact of adherence to the Mediterranean diet on CVD across risk categories. Methods and Results-In a post hoc analysis, we assessed the CVD predictive value of baseline estimated risk in 5966 PREDIMED participants (aged 55-74 years, 57% women; 48% with type 2 diabetes mellitus). Major CVD events, the primary PREDIMED end point, were an aggregate of myocardial infarction, stroke, and cardiovascular death. Multivariate-adjusted Cox regression was used to calculate hazard ratios for major CVD events and effect modification from the Mediterranean diet intervention across risk strata (low, moderate, high, very high). The Framingham-REGICOR classification of PREDIMED participants was 25.1% low risk, 44.5% moderate risk, and 30.4% high or very high risk. During 6-year follow-up, 188 major CVD events occurred. Hazard ratios for major CVD events increased in parallel with estimated risk (2.68, 4.24, and 6.60 for moderate, high, and very high risk), particularly in men (7.60, 13.16, and 15.85, respectively, versus 2.16, 2.28, and 3.51, respectively, in women). Yet among those with low or moderate risk, 32.2% and 74.3% of major CVD events occurred in men and women, respectively. Mediterranean diet adherence was associated with CVD risk reduction regardless of risk strata (P > 0.4 for interaction). Conclusions-Incident CVD increased in parallel with estimated risk in the PREDIMED cohort, but most events occurred in non- high-risk categories, particularly in women. Until predictive tools are improved, promotion of the Mediterranean diet might be useful to reduce CVD independent of baseline risk.This study was funded in part by Instituto de Salud Carlos III (ISCIII) (Spanish Ministry of Economy) through grants RTIC G03/140, RTIC RD 06/0045, Centro Nacional de Investigaciones Cardiovasculares CNIC 06/2007, ISCIII FIS PS09/01292, the Spanish Ministry of Science and Innovation (MICINN) AGL2010‐22319‐C03‐02 and AGL2009‐13906‐C02‐02, and an unrestricted grant from the California Walnut CommissionPeer ReviewedJohn Wiley & SonsInstituto de Salud Carlos IIICentro Nacional de Investigaciones Cardiovasculares (España)Ministerio de Ciencia e Innovación (España)California Walnut CommissionConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]2018201820172018info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionhttp://hdl.handle.net/10261/166179reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/MINECO/Plan Estatal de Investigación Científica y Técnica y de Innovación 2013-2016/AGL2010‐22319‐C03‐02 ; Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/1661792026-05-22T06:33:51Z
score	15,811543

Prediction of cardiovascular disease by the framingham-REGICOR equation in the high-risk PREDIMED cohort: Impact of the mediterranean diet across different risk strata

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