Ability to remotely monitor atrial high-rate episodes using a single-chamber implantable cardioverter-defibrillator with a floating atrial sensing dipole

Aims To allow timely initiation of anticoagulation therapy for the prevention of stroke, the European guidelines on atrial fibrillation (AF) recommend remote monitoring (RM) of device-detected atrial high-rate episodes (AHREs) and progression of arrhythmia duration along pre-specified strata (6 min....

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Autores: Hindricks, Gerhard, Theuns, Dominic A., Bar Lev, David, Anguera Camós, Ignasi, Ayala Paredes, Félix Alejandro, Arnold, Martin, Geller, J. Christoph, Merkely, Béla, Dyrda, Katia Marjolaine, Perings, Christian, Maglia, Giampiero, Ploux, Sylvain, Meyhöfer, Jürgen, BlomströmcLundqvist, Carina, Karjalainen, Pasi, Liang, Yanchun, Diemberger, Igor, Wranicz, Jerzy Krzysztof, Barr, Craig, Quartieri, Fabio, Timmel, Tobias, Bollmann, Andreas
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2023
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/205794
Acceso en línea:https://hdl.handle.net/2445/205794
Access Level:acceso abierto
Palabra clave:Anticoagulants (Medicina)
Fibril·lació auricular
Anticoagulants
Atrial Fibrillation
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spelling Ability to remotely monitor atrial high-rate episodes using a single-chamber implantable cardioverter-defibrillator with a floating atrial sensing dipoleHindricks, GerhardTheuns, Dominic A.Bar Lev, DavidAnguera Camós, IgnasiAyala Paredes, Félix AlejandroArnold, MartinGeller, J. ChristophMerkely, BélaDyrda, Katia MarjolainePerings, ChristianMaglia, GiampieroPloux, SylvainMeyhöfer, JürgenBlomströmcLundqvist, CarinaKarjalainen, PasiLiang, YanchunDiemberger, IgorWranicz, Jerzy KrzysztofBarr, CraigQuartieri, FabioTimmel, TobiasBollmann, AndreasAnticoagulants (Medicina)Fibril·lació auricularAnticoagulantsAtrial FibrillationAims To allow timely initiation of anticoagulation therapy for the prevention of stroke, the European guidelines on atrial fibrillation (AF) recommend remote monitoring (RM) of device-detected atrial high-rate episodes (AHREs) and progression of arrhythmia duration along pre-specified strata (6 min...<1h, 1 h...<24 h, >= 24h). We used the MATRIX registry data to assess the capability of a single-lead implantable cardioverter-defibrillator (ICD) with atrial sensing dipole (DX ICD system) to follow this recommendation in patients with standard indication for single-chamber ICD. Methods and results In 1841 DX ICD patients with daily automatic RM transmissions, electrograms of first device-detected AHREs per patient in each duration stratum were adjudicated, and the corresponding positive predictive values (PPVs) for the detections to be true atrial arrhythmia were calculated. Moreover, the incidence and progression of new-onset AF was assessed in 1451 patients with no AF history. A total of 610 AHREs >= 6min were adjudicated. The PPV was 95.1% (271 of 285) for episodes 6min...<1h, 99.6% (253/254) for episodes 1 h...<24h, 100% (71/71) for episodes >= 24h, or 97.5% for all episodes (595/610). The incidence of new-onset AF was 8.2% (119/1451), and in 31.1% of them (37/119), new-onset AF progressed to a higher duration stratum. Nearly 80% of new-onset AF patients had high CHA(2)DS(2)-VASc stroke risk, and 70% were not on anticoagulation therapy. Age was the only significant predictor of new-onset AF. Conclusion A 99.7% detection accuracy for AHRE >= 1h in patients with DX ICD systems in combination with daily RM allows a reliable guideline-recommended screening for subclinical AF and monitoring of AF-duration progression. [Graphics] .Oxford University Press (OUP)2024202420232024info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersion10 p.application/pdfhttps://hdl.handle.net/2445/205794Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))reponame:Recercat. Dipósit de la Recerca de Catalunyainstname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)InglésReproducció del document publicat a: https://doi.org/10.1093/europace/euad061Europace, 2023, vol. 25, num. 5https://doi.org/10.1093/europace/euad061cc by-nc (c) Hindricks, Gerhard et al., 2023http://creativecommons.org/licenses/by-nc/3.0/es/info:eu-repo/semantics/openAccessoai:recercat.cat:2445/2057942026-05-29T05:05:01Z
dc.title.none.fl_str_mv Ability to remotely monitor atrial high-rate episodes using a single-chamber implantable cardioverter-defibrillator with a floating atrial sensing dipole
title Ability to remotely monitor atrial high-rate episodes using a single-chamber implantable cardioverter-defibrillator with a floating atrial sensing dipole
spellingShingle Ability to remotely monitor atrial high-rate episodes using a single-chamber implantable cardioverter-defibrillator with a floating atrial sensing dipole
Hindricks, Gerhard
Anticoagulants (Medicina)
Fibril·lació auricular
Anticoagulants
Atrial Fibrillation
title_short Ability to remotely monitor atrial high-rate episodes using a single-chamber implantable cardioverter-defibrillator with a floating atrial sensing dipole
title_full Ability to remotely monitor atrial high-rate episodes using a single-chamber implantable cardioverter-defibrillator with a floating atrial sensing dipole
title_fullStr Ability to remotely monitor atrial high-rate episodes using a single-chamber implantable cardioverter-defibrillator with a floating atrial sensing dipole
title_full_unstemmed Ability to remotely monitor atrial high-rate episodes using a single-chamber implantable cardioverter-defibrillator with a floating atrial sensing dipole
title_sort Ability to remotely monitor atrial high-rate episodes using a single-chamber implantable cardioverter-defibrillator with a floating atrial sensing dipole
dc.creator.none.fl_str_mv Hindricks, Gerhard
Theuns, Dominic A.
Bar Lev, David
Anguera Camós, Ignasi
Ayala Paredes, Félix Alejandro
Arnold, Martin
Geller, J. Christoph
Merkely, Béla
Dyrda, Katia Marjolaine
Perings, Christian
Maglia, Giampiero
Ploux, Sylvain
Meyhöfer, Jürgen
BlomströmcLundqvist, Carina
Karjalainen, Pasi
Liang, Yanchun
Diemberger, Igor
Wranicz, Jerzy Krzysztof
Barr, Craig
Quartieri, Fabio
Timmel, Tobias
Bollmann, Andreas
author Hindricks, Gerhard
author_facet Hindricks, Gerhard
Theuns, Dominic A.
Bar Lev, David
Anguera Camós, Ignasi
Ayala Paredes, Félix Alejandro
Arnold, Martin
Geller, J. Christoph
Merkely, Béla
Dyrda, Katia Marjolaine
Perings, Christian
Maglia, Giampiero
Ploux, Sylvain
Meyhöfer, Jürgen
BlomströmcLundqvist, Carina
Karjalainen, Pasi
Liang, Yanchun
Diemberger, Igor
Wranicz, Jerzy Krzysztof
Barr, Craig
Quartieri, Fabio
Timmel, Tobias
Bollmann, Andreas
author_role author
author2 Theuns, Dominic A.
Bar Lev, David
Anguera Camós, Ignasi
Ayala Paredes, Félix Alejandro
Arnold, Martin
Geller, J. Christoph
Merkely, Béla
Dyrda, Katia Marjolaine
Perings, Christian
Maglia, Giampiero
Ploux, Sylvain
Meyhöfer, Jürgen
BlomströmcLundqvist, Carina
Karjalainen, Pasi
Liang, Yanchun
Diemberger, Igor
Wranicz, Jerzy Krzysztof
Barr, Craig
Quartieri, Fabio
Timmel, Tobias
Bollmann, Andreas
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Anticoagulants (Medicina)
Fibril·lació auricular
Anticoagulants
Atrial Fibrillation
topic Anticoagulants (Medicina)
Fibril·lació auricular
Anticoagulants
Atrial Fibrillation
description Aims To allow timely initiation of anticoagulation therapy for the prevention of stroke, the European guidelines on atrial fibrillation (AF) recommend remote monitoring (RM) of device-detected atrial high-rate episodes (AHREs) and progression of arrhythmia duration along pre-specified strata (6 min...<1h, 1 h...<24 h, >= 24h). We used the MATRIX registry data to assess the capability of a single-lead implantable cardioverter-defibrillator (ICD) with atrial sensing dipole (DX ICD system) to follow this recommendation in patients with standard indication for single-chamber ICD. Methods and results In 1841 DX ICD patients with daily automatic RM transmissions, electrograms of first device-detected AHREs per patient in each duration stratum were adjudicated, and the corresponding positive predictive values (PPVs) for the detections to be true atrial arrhythmia were calculated. Moreover, the incidence and progression of new-onset AF was assessed in 1451 patients with no AF history. A total of 610 AHREs >= 6min were adjudicated. The PPV was 95.1% (271 of 285) for episodes 6min...<1h, 99.6% (253/254) for episodes 1 h...<24h, 100% (71/71) for episodes >= 24h, or 97.5% for all episodes (595/610). The incidence of new-onset AF was 8.2% (119/1451), and in 31.1% of them (37/119), new-onset AF progressed to a higher duration stratum. Nearly 80% of new-onset AF patients had high CHA(2)DS(2)-VASc stroke risk, and 70% were not on anticoagulation therapy. Age was the only significant predictor of new-onset AF. Conclusion A 99.7% detection accuracy for AHRE >= 1h in patients with DX ICD systems in combination with daily RM allows a reliable guideline-recommended screening for subclinical AF and monitoring of AF-duration progression. [Graphics] .
publishDate 2023
dc.date.none.fl_str_mv 2023
2024
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://hdl.handle.net/2445/205794
url https://hdl.handle.net/2445/205794
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv Reproducció del document publicat a: https://doi.org/10.1093/europace/euad061
Europace, 2023, vol. 25, num. 5
https://doi.org/10.1093/europace/euad061
dc.rights.none.fl_str_mv cc by-nc (c) Hindricks, Gerhard et al., 2023
http://creativecommons.org/licenses/by-nc/3.0/es/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv cc by-nc (c) Hindricks, Gerhard et al., 2023
http://creativecommons.org/licenses/by-nc/3.0/es/
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 10 p.
application/pdf
dc.publisher.none.fl_str_mv Oxford University Press (OUP)
publisher.none.fl_str_mv Oxford University Press (OUP)
dc.source.none.fl_str_mv Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
reponame:Recercat. Dipósit de la Recerca de Catalunya
instname:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
instname_str Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
reponame_str Recercat. Dipósit de la Recerca de Catalunya
collection Recercat. Dipósit de la Recerca de Catalunya
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repository.mail.fl_str_mv
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