Innate immnunity on Antiphospholipid Syndrome : TLRs implication on imflammation

The main aim of this study is to evaluate the function of the TLRs and the expression levels of the genes involved in the TLR pathway on blood mononuclear cell populations from healthy controls and patients suffering of different subtypes of antiphospholipid syndrome, and then to be able to relate t...

Descripción completa

Detalles Bibliográficos
Autor: Franco González de Canales, Ana
Tipo de recurso: tesis de maestría
Fecha de publicación:2013
País:España
Institución:Universidad de Cantabria (UC)
Repositorio:UCrea Repositorio Abierto de la Universidad de Cantabria
Idioma:inglés
OAI Identifier:oai:repositorio.unican.es:10902/4191
Acceso en línea:http://hdl.handle.net/10902/4191
Access Level:acceso abierto
Palabra clave:Antiphospholipid syndrome
Receptores Tipo Toll
Toll-Like Receptors
id ES_58559f6c4c983a36346dbcafc8ee02bc
oai_identifier_str oai:repositorio.unican.es:10902/4191
network_acronym_str ES
network_name_str España
repository_id_str
spelling Innate immnunity on Antiphospholipid Syndrome : TLRs implication on imflammationFranco González de Canales, AnaAntiphospholipid syndromeReceptores Tipo TollToll-Like ReceptorsThe main aim of this study is to evaluate the function of the TLRs and the expression levels of the genes involved in the TLR pathway on blood mononuclear cell populations from healthy controls and patients suffering of different subtypes of antiphospholipid syndrome, and then to be able to relate those results with APS different clinical manifestations: Primary APS with vascular thrombosis, Primary APS with obstetric complications, Secondary APS, and Seropositive patients with no clinical manifestation. In case to confirm that this relation exists, we could really be sure that the innate immune responses have something to do with APS manifestation, and its molecular mechanisms would be closer to be known and better explained, which is really important for treatment development.Máster en Biología Molecular y BiomedicinaLópez Hoyos, MarcosUniversidad de Cantabria20132013-06-01master thesishttp://purl.org/coar/resource_type/c_bdccNAhttp://purl.org/coar/version/c_be7fb7dd8ff6fe43info:eu-repo/semantics/masterThesishttp://hdl.handle.net/10902/4191reponame:UCrea Repositorio Abierto de la Universidad de Cantabriainstname:Universidad de Cantabria (UC)Inglésengopen accesshttp://purl.org/coar/access_right/c_abf2Atribución-NoComercial-SinDerivadas 3.0 Españahttp://creativecommons.org/licenses/by-nc-nd/3.0/es/info:eu-repo/semantics/openAccessoai:repositorio.unican.es:10902/41912026-06-02T12:39:31Z
dc.title.none.fl_str_mv Innate immnunity on Antiphospholipid Syndrome : TLRs implication on imflammation
title Innate immnunity on Antiphospholipid Syndrome : TLRs implication on imflammation
spellingShingle Innate immnunity on Antiphospholipid Syndrome : TLRs implication on imflammation
Franco González de Canales, Ana
Antiphospholipid syndrome
Receptores Tipo Toll
Toll-Like Receptors
title_short Innate immnunity on Antiphospholipid Syndrome : TLRs implication on imflammation
title_full Innate immnunity on Antiphospholipid Syndrome : TLRs implication on imflammation
title_fullStr Innate immnunity on Antiphospholipid Syndrome : TLRs implication on imflammation
title_full_unstemmed Innate immnunity on Antiphospholipid Syndrome : TLRs implication on imflammation
title_sort Innate immnunity on Antiphospholipid Syndrome : TLRs implication on imflammation
dc.creator.none.fl_str_mv Franco González de Canales, Ana
author Franco González de Canales, Ana
author_facet Franco González de Canales, Ana
author_role author
dc.contributor.none.fl_str_mv López Hoyos, Marcos
Universidad de Cantabria
dc.subject.none.fl_str_mv Antiphospholipid syndrome
Receptores Tipo Toll
Toll-Like Receptors
topic Antiphospholipid syndrome
Receptores Tipo Toll
Toll-Like Receptors
description The main aim of this study is to evaluate the function of the TLRs and the expression levels of the genes involved in the TLR pathway on blood mononuclear cell populations from healthy controls and patients suffering of different subtypes of antiphospholipid syndrome, and then to be able to relate those results with APS different clinical manifestations: Primary APS with vascular thrombosis, Primary APS with obstetric complications, Secondary APS, and Seropositive patients with no clinical manifestation. In case to confirm that this relation exists, we could really be sure that the innate immune responses have something to do with APS manifestation, and its molecular mechanisms would be closer to be known and better explained, which is really important for treatment development.
publishDate 2013
dc.date.none.fl_str_mv 2013
2013-06-01
dc.type.none.fl_str_mv master thesis
http://purl.org/coar/resource_type/c_bdcc
NA
http://purl.org/coar/version/c_be7fb7dd8ff6fe43
dc.type.openaire.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
dc.identifier.none.fl_str_mv http://hdl.handle.net/10902/4191
url http://hdl.handle.net/10902/4191
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución-NoComercial-SinDerivadas 3.0 España
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
Atribución-NoComercial-SinDerivadas 3.0 España
http://creativecommons.org/licenses/by-nc-nd/3.0/es/
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:UCrea Repositorio Abierto de la Universidad de Cantabria
instname:Universidad de Cantabria (UC)
instname_str Universidad de Cantabria (UC)
reponame_str UCrea Repositorio Abierto de la Universidad de Cantabria
collection UCrea Repositorio Abierto de la Universidad de Cantabria
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869408535065919488
score 15.300719

Similares en LA Referencia