Different prognosis in hospitalized patients with influenza one season after the pandemic H1N1 influenza of 2009-2010 in Spain

Background The present report compares prognosis in hospitalized cases with the H1N1 pandemic virus in two seasons. Methods Two series of hospitalized patients with laboratory-confirmed H1N1 pandemic influenza have been compared: 813 in the season 2009-2010 and 707 in the season 2010-2011. A detaile...

Descripción completa

Detalles Bibliográficos
Autores: Delgado-Rodriguez, M, Castilla, J, Godoy, P, Martin, V, Soldevila, N, Alonso, J, Astray, J, Baricot, M, Galan, JC, Castro, A, Gonzalez-Candelas, F, Mayoral, JM, Quintana, JM, Pumarola, T, Tamames, S, Saez, M, Dominguez, A, Bonfill X., López-Contreras J., Pomar V., Puig T., CIBERESP Cases Controls Pandemic
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2013
País:España
Institución:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
Repositorio:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
OAI Identifier:oai:iibsantpau.fundanetsuite.com:p9577
Acceso en línea:https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=9577
Access Level:acceso abierto
Palabra clave:Hospitalization
influenza
mortality
prognosis
id ES_5843fb7ef91f22f2389a564e2bf13c4e
oai_identifier_str oai:iibsantpau.fundanetsuite.com:p9577
network_acronym_str ES
network_name_str España
repository_id_str
spelling Different prognosis in hospitalized patients with influenza one season after the pandemic H1N1 influenza of 2009-2010 in SpainDelgado-Rodriguez, MCastilla, JGodoy, PMartin, VSoldevila, NAlonso, JAstray, JBaricot, MGalan, JCCastro, AGonzalez-Candelas, FMayoral, JMQuintana, JMPumarola, TTamames, SSaez, MDominguez, ABonfill X.López-Contreras J.Pomar V.Puig T.CIBERESP Cases Controls PandemicHospitalizationinfluenzamortalityprognosisBackground The present report compares prognosis in hospitalized cases with the H1N1 pandemic virus in two seasons. Methods Two series of hospitalized patients with laboratory-confirmed H1N1 pandemic influenza have been compared: 813 in the season 2009-2010 and 707 in the season 2010-2011. A detailed history of variables preceding hospital admission and during hospitalization was obtained by interview and clinical charts. A combined endpoint of death admission to intensive care was used as outcome due to the low number of deaths. Logistic regression was applied in the analysis for adverse outcome. Results Patients of the second season had different characteristics than in the first one (older, more underlying conditions, more malfunctioning organs and more symptoms). Patients with H1N1 pandemic virus when hospitalized were more frequently directly admitted to ICU during the 2010-2011 season than in the previous season (RR = 2.10; 95% confidence intervals CI, 1.55-2.85), as a consequence of a higher presence of sepsis and respiratory distress. These patients also showed during hospitalization a higher risk of ICU admission or death (RR = 3.22, 95% CI, 2.15-4.83). After adjusting for the differences in risk factors of adverse outcome, patients in the second season showed a higher risk of ICU admission and/or in-hospital death odds ratio (OR = 3.77, 95% CI, 2.30-6.18). Conclusion Hospitalized patients with H1N1 pandemic influenza during the second season were more severely affected at hospital admission and showed a worse prognosis than in previous season, independently of the differences found at hospital admission.WILEY2013info:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionhttps://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=9577Influenza and Other Respiratory VirusesISSN: 17502640ISSNe: 17502659reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pauinstname:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)Inglésinfo:eu-repo/semantics/openAccessoai:iibsantpau.fundanetsuite.com:p95772026-06-14T12:41:47Z
dc.title.none.fl_str_mv Different prognosis in hospitalized patients with influenza one season after the pandemic H1N1 influenza of 2009-2010 in Spain
title Different prognosis in hospitalized patients with influenza one season after the pandemic H1N1 influenza of 2009-2010 in Spain
spellingShingle Different prognosis in hospitalized patients with influenza one season after the pandemic H1N1 influenza of 2009-2010 in Spain
Delgado-Rodriguez, M
Hospitalization
influenza
mortality
prognosis
title_short Different prognosis in hospitalized patients with influenza one season after the pandemic H1N1 influenza of 2009-2010 in Spain
title_full Different prognosis in hospitalized patients with influenza one season after the pandemic H1N1 influenza of 2009-2010 in Spain
title_fullStr Different prognosis in hospitalized patients with influenza one season after the pandemic H1N1 influenza of 2009-2010 in Spain
title_full_unstemmed Different prognosis in hospitalized patients with influenza one season after the pandemic H1N1 influenza of 2009-2010 in Spain
title_sort Different prognosis in hospitalized patients with influenza one season after the pandemic H1N1 influenza of 2009-2010 in Spain
dc.creator.none.fl_str_mv Delgado-Rodriguez, M
Castilla, J
Godoy, P
Martin, V
Soldevila, N
Alonso, J
Astray, J
Baricot, M
Galan, JC
Castro, A
Gonzalez-Candelas, F
Mayoral, JM
Quintana, JM
Pumarola, T
Tamames, S
Saez, M
Dominguez, A
Bonfill X.
López-Contreras J.
Pomar V.
Puig T.
CIBERESP Cases Controls Pandemic
author Delgado-Rodriguez, M
author_facet Delgado-Rodriguez, M
Castilla, J
Godoy, P
Martin, V
Soldevila, N
Alonso, J
Astray, J
Baricot, M
Galan, JC
Castro, A
Gonzalez-Candelas, F
Mayoral, JM
Quintana, JM
Pumarola, T
Tamames, S
Saez, M
Dominguez, A
Bonfill X.
López-Contreras J.
Pomar V.
Puig T.
CIBERESP Cases Controls Pandemic
author_role author
author2 Castilla, J
Godoy, P
Martin, V
Soldevila, N
Alonso, J
Astray, J
Baricot, M
Galan, JC
Castro, A
Gonzalez-Candelas, F
Mayoral, JM
Quintana, JM
Pumarola, T
Tamames, S
Saez, M
Dominguez, A
Bonfill X.
López-Contreras J.
Pomar V.
Puig T.
CIBERESP Cases Controls Pandemic
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.subject.none.fl_str_mv Hospitalization
influenza
mortality
prognosis
topic Hospitalization
influenza
mortality
prognosis
description Background The present report compares prognosis in hospitalized cases with the H1N1 pandemic virus in two seasons. Methods Two series of hospitalized patients with laboratory-confirmed H1N1 pandemic influenza have been compared: 813 in the season 2009-2010 and 707 in the season 2010-2011. A detailed history of variables preceding hospital admission and during hospitalization was obtained by interview and clinical charts. A combined endpoint of death admission to intensive care was used as outcome due to the low number of deaths. Logistic regression was applied in the analysis for adverse outcome. Results Patients of the second season had different characteristics than in the first one (older, more underlying conditions, more malfunctioning organs and more symptoms). Patients with H1N1 pandemic virus when hospitalized were more frequently directly admitted to ICU during the 2010-2011 season than in the previous season (RR = 2.10; 95% confidence intervals CI, 1.55-2.85), as a consequence of a higher presence of sepsis and respiratory distress. These patients also showed during hospitalization a higher risk of ICU admission or death (RR = 3.22, 95% CI, 2.15-4.83). After adjusting for the differences in risk factors of adverse outcome, patients in the second season showed a higher risk of ICU admission and/or in-hospital death odds ratio (OR = 3.77, 95% CI, 2.30-6.18). Conclusion Hospitalized patients with H1N1 pandemic influenza during the second season were more severely affected at hospital admission and showed a worse prognosis than in previous season, independently of the differences found at hospital admission.
publishDate 2013
dc.date.none.fl_str_mv 2013
dc.type.none.fl_str_mv info:eu-repo/semantics/article
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=9577
url https://iibsantpau.fundanetsuite.com/Publicaciones/ProdCientif/PublicacionFrw.aspx?id=9577
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv WILEY
publisher.none.fl_str_mv WILEY
dc.source.none.fl_str_mv Influenza and Other Respiratory Viruses
ISSN: 17502640
ISSNe: 17502659
reponame:r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname:Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
instname_str Institut d’Investigació Biomèdica Sant Pau (IIB Sant Pau)
reponame_str r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
collection r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
repository.name.fl_str_mv
repository.mail.fl_str_mv
_version_ 1869408530050580480
score 15.812429

Similares en LA Referencia