Automated blood glucose control in type 1 diabetes: A review of progress and challenges = Control automatizado de la glucosa en la diabetes tipo 1: revisión del progreso y los desafíos

Since the 2000s, research teams worldwide have been working to develop closedloop (CL) systems able to automatically control blood glucose (BG) levels in patients with type 1 diabetes. This emerging technology is known as artificial pancreas (AP), and its first commercial version just arrived in the...

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Detalhes bibliográficos
Autores: Bertachi, Arthur Hirata, Ramkissoon, Charrise Mary, Bondia, Jorge, Vehí, Josep
Formato: artículo
Estado:Versión aceptada para publicación
Fecha de publicación:2017
País:España
Recursos:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:10256/15011
Acesso em linha:http://hdl.handle.net/10256/15011
Access Level:acceso abierto
Palavra-chave:Diabetis -- Tractament
Diabetes -- Treatment
Pàncrees artificial
Artificial Pancreas
Control automàtic
Automatic control
Control intel·ligent
Intelligent control systems
Descrição
Resumo:Since the 2000s, research teams worldwide have been working to develop closedloop (CL) systems able to automatically control blood glucose (BG) levels in patients with type 1 diabetes. This emerging technology is known as artificial pancreas (AP), and its first commercial version just arrived in the market. The main objective of this paper is to present an extensive review of the clinical trials conducted since 2011, which tested various implementations of the AP for different durations under varying conditions. A comprehensive table that contains key information from the selected publications is provided, and the main challenges in AP development and the mitigation strategies used are discussed. The development timelines for different AP systems are also included, highlighting the main evolutions over the clinical trials for each system