Blood pressure values and depression in hypertensive individuals at high cardiovascular risk

BACKGROUND: Hypertension and depression are both important risk factors for cardiovascular diseases. Nevertheless, the association of blood pressure on and depression has not been completely established. This study aims to analyze whether depression may influence the control of blood pressure in hyp...

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Detalles Bibliográficos
Autores: Mejía-Lancheros, Cília, Estruch Riba, Ramon, Martínez-González, Miguel Ángel, 1957-, Salas Salvadó, Jordi, Corella Piquer, Dolores, Gómez Gracia, Enrique, Fiol Sala, Miguel, Santos, José Manuel, Fitó Colomer, Montserrat, Arós, Fernando, Serra Majem, Lluís, Pintó Sala, Xavier, Basora, Josep, Sorlí, José V., Muñoz Pérez, Miguel Ángel
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2014
País:España
Institución:Varias* (Consorci de Biblioteques Universitáries de Catalunya, Centre de Serveis Científics i Acadèmics de Catalunya)
Repositorio:Recercat. Dipósit de la Recerca de Catalunya
OAI Identifier:oai:recercat.cat:2445/121115
Acceso en línea:https://hdl.handle.net/2445/121115
Access Level:acceso abierto
Palabra clave:Hipertensió
Depressió psíquica
Malalties cardiovasculars
Pressió sanguínia
Assaigs clínics
Hypertension
Mental depression
Cardiovascular diseases
Blood pressure
Clinical trials
Descripción
Sumario:BACKGROUND: Hypertension and depression are both important risk factors for cardiovascular diseases. Nevertheless, the association of blood pressure on and depression has not been completely established. This study aims to analyze whether depression may influence the control of blood pressure in hypertensive individuals at high cardiovascular risk. METHODS: Cross-sectional study, embedded within the PREDIMED clinical trial, of 5954 hypertensive patients with high cardiovascular risk factor profiles. The relationship between blood pressure control and depression was analyzed. A multivariate analysis (logistic and log-linear regression), adjusting for potential confounders (socio-demographic factors, body mass index, lifestyle, diabetes, dyslipidemia, and antihypertensive treatment), was performed. RESULTS: Depressive patients, with and without antidepressant treatment, had better blood pressure control (OR: 1.28, CI 95%: 1.06-1.55, and OR: 1.30, CI 95%: 1.03-1.65, respectively) than non-depressive ones. Regarding blood pressure levels, systolic blood pressure values (mmHg) were found to be lower in both treated and untreated depressive patients (Log coefficient Beta: -1.59, 95% CI: -0.50 to -2.69 and Log coefficient Beta: -3.49, 95% CI: -2.10 to -4.87, respectively). CONCLUSIONS: Among hypertensive patients at high cardiovascular risk, the control of blood pressure was better in those diagnosed with depression. TRIAL REGISTRATION: Unique identifier: ISRCTN35739639.

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