Interventional programmes to improve cognition during healthy and pathological ageing: Cortical modulations and evidence for brain plasticity

Available online 06 March 2018

Detalhes bibliográficos
Autores: Cespón, Jesús, Miniussi, Carlo, Pellicciari, Maria Concetta
Formato: artículo
Fecha de publicación:2018
País:España
Recursos:Universidad del País Vasco
Repositorio:Addi. Archivo Digital para la Docencia y la Investigación
OAI Identifier:oai:addi.ehu.eus:10810/25639
Acesso em linha:http://hdl.handle.net/10810/25639
Access Level:acceso abierto
Palavra-chave:Ageing
Alzheimer’s disease
Neuroplasticity
Non-pharmacological interventions
Cognitive reserve
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spelling Interventional programmes to improve cognition during healthy and pathological ageing: Cortical modulations and evidence for brain plasticityCespón, JesúsMiniussi, CarloPellicciari, Maria ConcettaAgeingAlzheimer’s diseaseNeuroplasticityNon-pharmacological interventionsCognitive reserveAvailable online 06 March 2018A growing body of evidence suggests that healthy elderly individuals and patients with Alzheimer’s disease retain an important potential for neuroplasticity. This review summarizes studies investigating the modulation of neural activity and structural brain integrity in response to interventions involving cognitive training, physical exercise and non-invasive brain stimulation in healthy elderly and cognitively impaired subjects (including patients with mild cognitive impairment (MCI) and Alzheimer’s disease). Moreover, given the clinical relevance of neuroplasticity, we discuss how evidence for neuroplasticity can be inferred from the functional and structural brain changes observed after implementing these interventions. We emphasize that multimodal programmes, which combine several types of interventions, improve cognitive function to a greater extent than programmes that use a single interventional approach. We suggest specific methods for weighting the relative importance of cognitive training, physical exercise and non-invasive brain stimulation according to the functional and structural state of the brain of the targeted subject to maximize the cognitive improvements induced by multimodal programmes.This study was funded by the European Commission Marie-Skłodowska Curie Actions, Individual Fellowships; 655423-NIBSAD, Italian Ministry of HealthGR-2011-02349998, and Galician government (Postdoctoral Grants Plan I2C 2011-2015).Ageing Research Reviews201820182018info:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10810/25639reponame:Addi. Archivo Digital para la Docencia y la Investigacióninstname:Universidad del País VascoInglésinfo:eu-repo/grantAgreement/EC/H2020/655423www.elsevier.com/locate/arrinfo:eu-repo/semantics/openAccess© 2018 Elsevier B.V. All rights reserved.oai:addi.ehu.eus:10810/256392026-06-18T09:23:17Z
dc.title.none.fl_str_mv Interventional programmes to improve cognition during healthy and pathological ageing: Cortical modulations and evidence for brain plasticity
title Interventional programmes to improve cognition during healthy and pathological ageing: Cortical modulations and evidence for brain plasticity
spellingShingle Interventional programmes to improve cognition during healthy and pathological ageing: Cortical modulations and evidence for brain plasticity
Cespón, Jesús
Ageing
Alzheimer’s disease
Neuroplasticity
Non-pharmacological interventions
Cognitive reserve
title_short Interventional programmes to improve cognition during healthy and pathological ageing: Cortical modulations and evidence for brain plasticity
title_full Interventional programmes to improve cognition during healthy and pathological ageing: Cortical modulations and evidence for brain plasticity
title_fullStr Interventional programmes to improve cognition during healthy and pathological ageing: Cortical modulations and evidence for brain plasticity
title_full_unstemmed Interventional programmes to improve cognition during healthy and pathological ageing: Cortical modulations and evidence for brain plasticity
title_sort Interventional programmes to improve cognition during healthy and pathological ageing: Cortical modulations and evidence for brain plasticity
dc.creator.none.fl_str_mv Cespón, Jesús
Miniussi, Carlo
Pellicciari, Maria Concetta
author Cespón, Jesús
author_facet Cespón, Jesús
Miniussi, Carlo
Pellicciari, Maria Concetta
author_role author
author2 Miniussi, Carlo
Pellicciari, Maria Concetta
author2_role author
author
dc.subject.none.fl_str_mv Ageing
Alzheimer’s disease
Neuroplasticity
Non-pharmacological interventions
Cognitive reserve
topic Ageing
Alzheimer’s disease
Neuroplasticity
Non-pharmacological interventions
Cognitive reserve
description Available online 06 March 2018
publishDate 2018
dc.date.none.fl_str_mv 2018
2018
2018
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv http://hdl.handle.net/10810/25639
url http://hdl.handle.net/10810/25639
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv info:eu-repo/grantAgreement/EC/H2020/655423
www.elsevier.com/locate/arr
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
© 2018 Elsevier B.V. All rights reserved.
eu_rights_str_mv openAccess
rights_invalid_str_mv © 2018 Elsevier B.V. All rights reserved.
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Ageing Research Reviews
publisher.none.fl_str_mv Ageing Research Reviews
dc.source.none.fl_str_mv reponame:Addi. Archivo Digital para la Docencia y la Investigación
instname:Universidad del País Vasco
instname_str Universidad del País Vasco
reponame_str Addi. Archivo Digital para la Docencia y la Investigación
collection Addi. Archivo Digital para la Docencia y la Investigación
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,300719

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