Establishment of a human iPSC line, IISHDOi004-A, from a patient with Usher syndrome associated with the mutation c.2276G>T

A human iPSC line, IISHDOi004-A, from fibroblasts obtained from a patient with Usher syndrome, harboring a homozygous mutation in the USH2A gene (c.2276G>T; p.Cys759Phe) has been generated. Reprogramming factors Oct3/4, Sox2, Klf4, and c-Myc were delivered using Sendai virus.

Detalles Bibliográficos
Autores: Zurita-Díaz, Francisco, Ortuño-Costela, María del Carmen, Moreno-Izquierdo, Ana, Galbis, Liliana, Millán, José María, Ayuso García, María del Carmen Tomasa, Garesse Alarcón, Rafael, Gallardo, M. Esther
Tipo de recurso: artículo
Fecha de publicación:2018
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/687573
Acceso en línea:http://hdl.handle.net/10486/687573
https://dx.doi.org/10.1016/j.scr.2018.08.002
Access Level:acceso abierto
Palabra clave:Human iPSC line
Fibroblasts
Usher syndrome
Mutation in the USH2A
Biología y Biomedicina / Biología
Descripción
Sumario:A human iPSC line, IISHDOi004-A, from fibroblasts obtained from a patient with Usher syndrome, harboring a homozygous mutation in the USH2A gene (c.2276G>T; p.Cys759Phe) has been generated. Reprogramming factors Oct3/4, Sox2, Klf4, and c-Myc were delivered using Sendai virus.

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