Lycopene in citrus fruit: biochemical mechanisms, molecular insights and health implications

Accumulation of the carotene lycopene in Citrus is an unusual trait found in a limited number of pummelos, grapefruits, oranges, lemons and related hybrids, imparting a distinctive pink-to-red color to the fruit. This phenotype most often arises from spontaneous bud-sport mutations and is generally...

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Detalles Bibliográficos
Autores: Zacarías-García, Jaime, Karp, David, Roberts, Jon, Tornero Raga, Carlos, Zacarías, Lorenzo, Rodrigo, María Jesús
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2026
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/421055
Acceso en línea:http://hdl.handle.net/10261/421055
https://api.elsevier.com/content/abstract/scopus_id/105030341921
Access Level:acceso abierto
Palabra clave:Carotenoids
Citrus
Health benefits
Lycopene
Pink-fleshed fruit
carotenoids
health
Descripción
Sumario:Accumulation of the carotene lycopene in Citrus is an unusual trait found in a limited number of pummelos, grapefruits, oranges, lemons and related hybrids, imparting a distinctive pink-to-red color to the fruit. This phenotype most often arises from spontaneous bud-sport mutations and is generally confined to the inner fruit tissues (endocarp), although in some cultivars lycopene is also found in the rind (flavedo) or albedo. Pink-fleshed cultivars typically show an altered carotenoid profile, particularly in the pulp, with higher total carotenoid levels than their parental or standard counterparts. Comparative analyses across citrus species and cultivars reveal both shared and distinct patterns in carotenoid accumulation and tissue-specific pigmentation. The genetic and molecular bases of these changes are not yet fully resolved and appear to differ among species and cultivars. Beyond their scientific interest, these cultivars present promising opportunities for commercial development due to their striking coloration and provide enhanced nutritional value because of their high carotenoid levels. This review integrates and compares evidence from multiple citrus species and cultivars on the origin and diversity of lycopene-accumulating Citrus, their characteristic carotenoid composition, the proposed molecular and biochemical mechanisms leading to lycopene accumulation, and the nutritional and health implications of pink-fleshed cultivars.