Demographic and clinical profile of idiopathic pulmonary fibrosis patients in Spain: the SEPAR National Registry

BackgroundLittle is known on the characteristics of patients diagnosed with idiopathic pulmonary fibrosis (IPF) in Spain. We aimed to characterize the demographic and clinical profile of IPF patients included in the IPF National Registry of the Spanish Respiratory Society (SEPAR).MethodsThis is a pr...

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Detalles Bibliográficos
Autores: Fernandez-Fabrellas, Estrella, Molina-Molina, Maria, Soriano, Joan B., Rodriguez Portal, Jose Antonio, Ancochea, Julio, Valenzuela, Claudia, Xaubet, Antoni, Aburto Barrenetxea, M., Alfageme, Inmaculada, Bollo de Miguel, E., Cano, E., Casanova Espinosa, A., Castillo Villegas, D., Figuerola Mendal, J. A., Garcia Sevila, R., Gaudo Navarro, J., I, Gomez Carrera, L., Gonzalez, J. M., Herrera Lara, Susana, Laporta Hernandez, R., Marin Gonzalez, M., Nieto Barbero, M. A., Portillo, K., Romero, A. D., Sanchez Simon-Talero, R., Sancho Chust, J. N., Sellares Torres, J., Soler Sempere, M. J., Sauleda, Jaume, Tomas Lopez, L., Villanueva Montes, M., SEPAR-IPF Natl Registry
Tipo de recurso: artículo
Fecha de publicación:2019
País:España
Institución:Conselleria de Salut i Consum del Govern de les Illes Balears
Repositorio:Docusalut
Idioma:inglés
OAI Identifier:oai:docusalut.com:20.500.13003/11830
Acceso en línea:https://hdl.handle.net/20.500.13003/11830
Access Level:acceso abierto
Palabra clave:Registries
Retrospective Studies
Aged, 80 and over
Aged
Spain
Pyridones
Humans
Anti-Inflammatory Agents, Non-Steroidal
Middle Aged
Male
Prospective Studies
Female
Idiopathic Pulmonary Fibrosis
Societies, Medical
Sistema de Registros
Femenino
Sociedades Médicas
Masculino
Piridonas
Humanos
Persona de Mediana Edad
Estudios Prospectivos
Antiinflamatorios no Esteroideos
Anciano
Anciano de 80 o más Años
Estudios Retrospectivos
Fibrosis Pulmonar Idiopática
España
Anti-fibrotic treatment
Idiopathic pulmonary fibrosis
National registry
SEPAR
Descripción
Sumario:BackgroundLittle is known on the characteristics of patients diagnosed with idiopathic pulmonary fibrosis (IPF) in Spain. We aimed to characterize the demographic and clinical profile of IPF patients included in the IPF National Registry of the Spanish Respiratory Society (SEPAR).MethodsThis is a prospective, observational, multicentre and nationwide study that involved 608 IPF patients included in the SEPAR IPF Registry up to June 27th, 2017, and who received any treatment for their disease. IPF patients were predominantly males, ex-smokers, and aged in their 70s, similar to other registries.ResultsUpon inclusion, meanSD predicted forced vital capacity was 77.6%+/- 19.4, diffusing capacity for carbon monoxide was 48.5%+/- 17.7, and the 6-min walk distance was 423.5m +/- 110.4. The diagnosis was mainly established on results from the high-resolution computed tomography in the proper clinical context (55.0% of patients), while 21.2% of patients required invasive procedures (surgical lung biopsy) for definitive diagnosis. Anti-fibrotic treatment was prescribed in 69.4% of cases, 51.5% pirfenidone and 17.9% nintedanib, overall with a good safety profile.Conclusions The SEPAR IPF Registry should help to further characterize current characteristics and future trends of IPF patients in Spain and compare/pool them with other registries and cohorts.

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