Dramatic reduction of ventricular tachycardia burden after dronedarone plus mexiletine treatment in a patient refractory to hybrid ablation

[EN] Antiarrhythmic drugs are often the last resort for recurrent ventricular tachycardia refractory to catheter ablation in implantable cardioverter-defibrillator carriers. Amiodarone, alone or combined with mexiletine, is usually but not always highly effective, and its use is usually limited by s...

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Bibliographic Details
Authors: Frutos‐López, Manuel, Pedrote, Alonso, Acosta, Juan, Arana-Rueda, Eduardo
Format: article
Status:Published version
Publication Date:2020
Country:España
Institution:Consejo Superior de Investigaciones Científicas (CSIC)
Repository:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/237722
Online Access:http://hdl.handle.net/10261/237722
Access Level:Open access
Keyword:Dronedarone
Mexiletine
Ventricular arrhythmias
Catheter ablation
Antiarrhythmic drugs
Dronedarona
Mexiletina
Arritmias ventriculares
Ablação por cateter
Fármacos anti-arrítmicos
Description
Summary:[EN] Antiarrhythmic drugs are often the last resort for recurrent ventricular tachycardia refractory to catheter ablation in implantable cardioverter-defibrillator carriers. Amiodarone, alone or combined with mexiletine, is usually but not always highly effective, and its use is usually limited by systemic adverse effects. We present the case of a 62 years old man with recurrent ICD shocks due to a VT refractory to an endo-epicardial hybrid ablation. Starting of dronedarone plus mexiletine combination showed an excellent result.