Anti-inflammatory and regenerative effects of MKARE® Eggshell Membrane: An in vitro osteoarthritis model and placebo-controlled clinical study

[EN]MKARE®, a 100% natural ingredient derived from fresh eggshell membrane (ESM), has a rich composition in bioactive compounds like collagen, hyaluronic acid, and elastin. These components are beneficial for managing osteoarthritis (OA) due to their anti-inflammatory and regenerative properties. Hi...

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Detalhes bibliográficos
Autores: Casado Santos, Alejandro, La Nuez-García, Manuel A., Álvarez Rodríguez, Patricia, González Cubero, Elsa, González Rodríguez, Yaiza, González Fernández, María Luisa, Villar Suárez, María Vega
Tipo de documento: artigo
Estado:Versão publicada
Data de publicação:2024
País:España
Recursos:Universidad Rey Juan Carlos
Repositório:BULERIA. Repositorio Institucional de la Universidad de León
OAI Identifier:oai:buleria.unileon.es:10612/19231
Acesso em linha:https://hdl.handle.net/10612/19231
Access Level:Acceso aberto
Palavra-chave:Veterinaria
Eggshell
Eggshell membrane
Osteoarthritis
Pain
Chondrocytes
3109.01 Anatomía
Descrição
Resumo:[EN]MKARE®, a 100% natural ingredient derived from fresh eggshell membrane (ESM), has a rich composition in bioactive compounds like collagen, hyaluronic acid, and elastin. These components are beneficial for managing osteoarthritis (OA) due to their anti-inflammatory and regenerative properties. Highlighting the significance of freshness, our research has shown that the effectiveness of MKARE® is higher than that of other commercial products based on ESM that have been stored for several days at room temperature, losing their bioactive compounds. This study explores the MKARE® anti-inflammatory capacity through an in vitro and clinical analyses, demonstrating its ability to alleviate OA symptoms and improve joint health. This underscores the crucial role of freshness in optimizing the therapeutic benefits.