Combined use of Radiofrequency ablation and hysteroscopy in the treatment of uterine Myomas: An innovative approach

Objective: To evaluate transvaginal radiofrequency ablation (TRFA) as a preoperative strategy to facilitate hysteroscopic resection in patients with complex submucosal fibroids desiring uterine preservation. Design: Prospective case series. Setting: Single tertiary hospital (Puerta de Hierro Univers...

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Detalles Bibliográficos
Autores: Marín Martínez, María Eugenia, Vaquero Argüello, Gema, Pérez Medina, Tirso, Calles Sastre, Laura Beatriz, Cruz Conty, María Luisa de la, Cruz Melguizo, Sara
Tipo de recurso: artículo
Fecha de publicación:2025
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:dnet:biblosearchi::bc68139f684a698bf7f249de03704112
Acceso en línea:https://hdl.handle.net/10486/777081
https://dx.doi.org/10.1016/j.ejogrb.2025.114673
Access Level:acceso abierto
Palabra clave:Uterine fibroids
Submucosal myoma
Radiofrequency ablation
Hysteroscopic myomectomy
Minimally invasive surgery
Fertility-sparing treatment
Medicina
Descripción
Sumario:Objective: To evaluate transvaginal radiofrequency ablation (TRFA) as a preoperative strategy to facilitate hysteroscopic resection in patients with complex submucosal fibroids desiring uterine preservation. Design: Prospective case series. Setting: Single tertiary hospital (Puerta de Hierro University Hospital, Madrid, Spain), January 2021–June 2023. Participants: Thirteen women with a single symptomatic fibroid containing a submucosal component, Lasmar- STEPW score ≥ 5, and no pregnancy desire for at least one year. Interventions: TRFA was performed under general anaesthesia in an outpatient setting. Hysteroscopic myomectomy was scheduled from the sixth month onward. Outcomes included fibroid volume reduction, symptom improvement (Uterine Fibroid Symptom and Quality of Life questionnaire [UFS-QoL]), and hysteroscopic resection feasibility. Results: Median age was 43 years. All TRFA procedures were completed successfully. At 6 months, median fibroid volume reduction was 76.8 %. UFS-QoL significantly improved (median from 32 to 14; p = 0.004). Complete hysteroscopic resection was achieved in 12 of 13 patients (92.3 %). One patient without fibroid regression required laparotomic myomectomy, with final diagnosis of adenomyoma. No serious complications or symptom recurrence were observed at follow-up. Conclusion: TRFA is a safe, effective outpatient technique that significantly reduces fibroid volume and facilitates complete hysteroscopic resection in women with complex submucosal fibroids. This combined approach may expand the role of conservative vaginal surgery in selected patients