COVID-19 in patients with haematologic malignancies: Effect of RNAemia on clinical outcome in vaccinated patients

Patients with haematologic malignancies (HM) COVID-19 have more severe disease, with increased risk of mortality. Therefore, this study aimed to evaluate the effect of SARS-CoV-2 RNAemia and the specific humoral immune responses on the clinical outcomes of patients with HM and COVID-19.

Detalles Bibliográficos
Autores: Martín-Escolano, Javier, Salto-Alejandre, Sonsoles, Infante-Domínguez, Carmen, Carretero-Ledesma, Marta, Maldonado-Lizarazo, Natalia, Camacho-Martínez, Pedro, Martín-Domínguez, Francisco, Tallón-Ruiz, Inmaculada, Ruiz-Molina, Ana, Palacios-Baena, Zaira Raquel, Pérez-Palacios, Patricia, Paniagua-García, María, Álvarez-Marín, Rocío, Merino, Laura, Cisneros, José Miguel, Cordero, Elisa, Pachón, Jerónimo, Pérez-Simón, José A., Sánchez-Céspedes, Javier, Aguilar-Guisado, Manuela
Tipo de recurso: artículo
Estado:Versión publicada
Fecha de publicación:2024
País:España
Institución:Consejo Superior de Investigaciones Científicas (CSIC)
Repositorio:DIGITAL.CSIC. Repositorio Institucional del CSIC
OAI Identifier:oai:digital.csic.es:10261/368562
Acceso en línea:http://hdl.handle.net/10261/368562
https://api.elsevier.com/content/abstract/scopus_id/85199331535
Access Level:acceso abierto
Palabra clave:COVID-19
Clinical outcome
Haematologic malignancies
RNAemia
SARS-CoV-2
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spelling COVID-19 in patients with haematologic malignancies: Effect of RNAemia on clinical outcome in vaccinated patientsMartín-Escolano, JavierSalto-Alejandre, SonsolesInfante-Domínguez, CarmenCarretero-Ledesma, MartaMaldonado-Lizarazo, NataliaCamacho-Martínez, PedroMartín-Domínguez, FranciscoTallón-Ruiz, InmaculadaRuiz-Molina, AnaPalacios-Baena, Zaira RaquelPérez-Palacios, PatriciaPaniagua-García, MaríaÁlvarez-Marín, RocíoMerino, LauraCisneros, José MiguelCordero, ElisaPachón, JerónimoPérez-Simón, José A.Sánchez-Céspedes, JavierAguilar-Guisado, ManuelaCOVID-19Clinical outcomeHaematologic malignanciesRNAemiaSARS-CoV-2Patients with haematologic malignancies (HM) COVID-19 have more severe disease, with increased risk of mortality. Therefore, this study aimed to evaluate the effect of SARS-CoV-2 RNAemia and the specific humoral immune responses on the clinical outcomes of patients with HM and COVID-19.This study was supported by Plan Nacional de I+D+i 2013‐2016 and Instituto de Salud Carlos III, Subdirección General de Redes y Centros de Investigación Cooperativa, Ministerio de Ciencia, Innovación y Universidades, Spanish Network for Research in Infectious Diseases ( REIPI RD16/0016/0009 ); co‐financed by European Development Regional Fund ‘A way to achieve Europe’, Operative Program Intelligence Growth 2014‐2020; and supported by the grant PI21/01569 from the Instituto de Salud Carlos III and the grant IM22/INF/13 from the CIBERINFEC, Instituto de Salud Carlos III, Spain. RA-M, LM, JMC, EC, JS-C and MA-G ( CB21/13/00006 ) and ZRP-B, and PP-P ( CB21/13/00012 ) were also supported by CIBERINFEC – Consorcio Centro de Investigación Biomédica en Red, Instituto de Salud Carlos III, Ministerio de Ciencia e Innovación and Unión Europea – NextGenerationEU. JM-E was supported by a predoctoral health research training contracts from the Instituto de Salud Carlos III ( FI22/00025 ). JS-C is a researcher belonging to the program ‘Nicolás Monardes’ (C-0059-2018), Servicio Andaluz de Salud, Junta de Andalucía, Spain.Peer reviewedElsevierInstituto de Salud Carlos IIIMinisterio de Ciencia, Innovación y Universidades (España)European CommissionJunta de AndalucíaConsejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]202420242024info:eu-repo/semantics/articlehttp://purl.org/coar/resource_type/c_6501Publisher's versioninfo:eu-repo/semantics/publishedVersionapplication/pdfhttp://hdl.handle.net/10261/368562https://api.elsevier.com/content/abstract/scopus_id/85199331535reponame:DIGITAL.CSIC. Repositorio Institucional del CSICinstname:Consejo Superior de Investigaciones Científicas (CSIC)Inglés#PLACEHOLDER_PARENT_METADATA_VALUE#info:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI21%2F01569The underlying dataset has been published as supplementary material of the article in the publisher platform at https://doi.org/10.1016/j.ijid.2024.107163https://doi.org/10.1016/j.ijid.2024.107163Síinfo:eu-repo/semantics/openAccessoai:digital.csic.es:10261/3685622026-05-22T06:33:51Z
dc.title.none.fl_str_mv COVID-19 in patients with haematologic malignancies: Effect of RNAemia on clinical outcome in vaccinated patients
title COVID-19 in patients with haematologic malignancies: Effect of RNAemia on clinical outcome in vaccinated patients
spellingShingle COVID-19 in patients with haematologic malignancies: Effect of RNAemia on clinical outcome in vaccinated patients
Martín-Escolano, Javier
COVID-19
Clinical outcome
Haematologic malignancies
RNAemia
SARS-CoV-2
title_short COVID-19 in patients with haematologic malignancies: Effect of RNAemia on clinical outcome in vaccinated patients
title_full COVID-19 in patients with haematologic malignancies: Effect of RNAemia on clinical outcome in vaccinated patients
title_fullStr COVID-19 in patients with haematologic malignancies: Effect of RNAemia on clinical outcome in vaccinated patients
title_full_unstemmed COVID-19 in patients with haematologic malignancies: Effect of RNAemia on clinical outcome in vaccinated patients
title_sort COVID-19 in patients with haematologic malignancies: Effect of RNAemia on clinical outcome in vaccinated patients
dc.creator.none.fl_str_mv Martín-Escolano, Javier
Salto-Alejandre, Sonsoles
Infante-Domínguez, Carmen
Carretero-Ledesma, Marta
Maldonado-Lizarazo, Natalia
Camacho-Martínez, Pedro
Martín-Domínguez, Francisco
Tallón-Ruiz, Inmaculada
Ruiz-Molina, Ana
Palacios-Baena, Zaira Raquel
Pérez-Palacios, Patricia
Paniagua-García, María
Álvarez-Marín, Rocío
Merino, Laura
Cisneros, José Miguel
Cordero, Elisa
Pachón, Jerónimo
Pérez-Simón, José A.
Sánchez-Céspedes, Javier
Aguilar-Guisado, Manuela
author Martín-Escolano, Javier
author_facet Martín-Escolano, Javier
Salto-Alejandre, Sonsoles
Infante-Domínguez, Carmen
Carretero-Ledesma, Marta
Maldonado-Lizarazo, Natalia
Camacho-Martínez, Pedro
Martín-Domínguez, Francisco
Tallón-Ruiz, Inmaculada
Ruiz-Molina, Ana
Palacios-Baena, Zaira Raquel
Pérez-Palacios, Patricia
Paniagua-García, María
Álvarez-Marín, Rocío
Merino, Laura
Cisneros, José Miguel
Cordero, Elisa
Pachón, Jerónimo
Pérez-Simón, José A.
Sánchez-Céspedes, Javier
Aguilar-Guisado, Manuela
author_role author
author2 Salto-Alejandre, Sonsoles
Infante-Domínguez, Carmen
Carretero-Ledesma, Marta
Maldonado-Lizarazo, Natalia
Camacho-Martínez, Pedro
Martín-Domínguez, Francisco
Tallón-Ruiz, Inmaculada
Ruiz-Molina, Ana
Palacios-Baena, Zaira Raquel
Pérez-Palacios, Patricia
Paniagua-García, María
Álvarez-Marín, Rocío
Merino, Laura
Cisneros, José Miguel
Cordero, Elisa
Pachón, Jerónimo
Pérez-Simón, José A.
Sánchez-Céspedes, Javier
Aguilar-Guisado, Manuela
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Instituto de Salud Carlos III
Ministerio de Ciencia, Innovación y Universidades (España)
European Commission
Junta de Andalucía
Consejo Superior de Investigaciones Científicas [https://ror.org/02gfc7t72]
dc.subject.none.fl_str_mv COVID-19
Clinical outcome
Haematologic malignancies
RNAemia
SARS-CoV-2
topic COVID-19
Clinical outcome
Haematologic malignancies
RNAemia
SARS-CoV-2
description Patients with haematologic malignancies (HM) COVID-19 have more severe disease, with increased risk of mortality. Therefore, this study aimed to evaluate the effect of SARS-CoV-2 RNAemia and the specific humoral immune responses on the clinical outcomes of patients with HM and COVID-19.
publishDate 2024
dc.date.none.fl_str_mv 2024
2024
2024
dc.type.none.fl_str_mv info:eu-repo/semantics/article
http://purl.org/coar/resource_type/c_6501
Publisher's version
info:eu-repo/semantics/publishedVersion
format article
status_str publishedVersion
dc.identifier.none.fl_str_mv http://hdl.handle.net/10261/368562
https://api.elsevier.com/content/abstract/scopus_id/85199331535
url http://hdl.handle.net/10261/368562
https://api.elsevier.com/content/abstract/scopus_id/85199331535
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.relation.none.fl_str_mv #PLACEHOLDER_PARENT_METADATA_VALUE#
info:eu-repo/grantAgreement/ISCIII/Plan Estatal de Investigación Científica y Técnica y de Innovación 2017-2020 (ISCIII)/PI21%2F01569
The underlying dataset has been published as supplementary material of the article in the publisher platform at https://doi.org/10.1016/j.ijid.2024.107163
https://doi.org/10.1016/j.ijid.2024.107163
Sí
dc.rights.none.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:DIGITAL.CSIC. Repositorio Institucional del CSIC
instname:Consejo Superior de Investigaciones Científicas (CSIC)
instname_str Consejo Superior de Investigaciones Científicas (CSIC)
reponame_str DIGITAL.CSIC. Repositorio Institucional del CSIC
collection DIGITAL.CSIC. Repositorio Institucional del CSIC
repository.name.fl_str_mv
repository.mail.fl_str_mv
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