Regulating reproductive genetic services: dealing with spiral-shaped processes and techno-scientific imaginaries

Purpose We have been inquiring into the diffusion process of reproductive genetic services (RGS) and the viability of geneticization in human reproduction. Method A 2-round modified-Delphi survey was applied amongst Israeli and Spanish experts to analyze regulatory attitudes and expectations about t...

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Detalles Bibliográficos
Autores: Alon, Ido, Urbanos Garrido, Rosa, Guimón de Ros, José
Tipo de recurso: artículo
Fecha de publicación:2021
País:España
Institución:Universidad Autónoma de Madrid
Repositorio:Biblos-e Archivo. Repositorio Institucional de la UAM
Idioma:inglés
OAI Identifier:oai:repositorio.uam.es:10486/726300
Acceso en línea:https://hdl.handle.net/10486/726300
https://dx.doi.org/10.1007/s10815-020-02017-9
Access Level:acceso abierto
Palabra clave:Assisted reproductive technologies
Reproductive genetic services
Diffusion of innovation
Regulating emerging technologies
Delphi
Preimplantation genetic testing
Biología y Biomedicina / Biología
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spelling Regulating reproductive genetic services: dealing with spiral-shaped processes and techno-scientific imaginariesAlon, IdoUrbanos Garrido, RosaGuimón de Ros, JoséAssisted reproductive technologiesReproductive genetic servicesDiffusion of innovationRegulating emerging technologiesDelphiPreimplantation genetic testingBiología y Biomedicina / BiologíaPurpose We have been inquiring into the diffusion process of reproductive genetic services (RGS) and the viability of geneticization in human reproduction. Method A 2-round modified-Delphi survey was applied amongst Israeli and Spanish experts to analyze regulatory attitudes and expectations about the future applications of RGS. We argue that an explanation of RGS diffusion based on a ‘technology-push’ impulse should be complemented by a ‘demandpull’ approach, which underscores the importance of regulatory frameworks and demand-inducing policies. The diffusion of RGS is advancing in a ‘spiralshaped’ process where technology acts as a cause and effect simultaneously, modulating social acceptance and redefining the notions of health and responsibility along the way. Results We suggest that there is a ‘grey-zone’ of RGS regulations regarding four procedures: the use of germline genome modification (GGM) for severe monogenic disorders, preimplantation genetic testing (PGT) for detection of chromosomal abnormalities, PGT for multifactorial diseases, and PGT with whole-exome screening. Conclusions Although far from the geneticization of human reproduction, our findings suggest that, since techno-scientific imaginaries tend to shape regulations and thus favor the diffusion of RGS, policymakers should pay attention to those procedures by focusing on good practices and equity while providing sound information on potential risks and expected success rates. A broad and inclusive societal debate is critical for overcoming the difficulty of drawing a clear line between medical and nonmedical uses of genetic selection and engineering while searching for the right balance between allowing reproductive autonomy and protecting the public interestSpringerDepartamento de Estructura Económica y Economía del DesarrolloFacultad de Ciencias Económicas y Empresariales20212021-06-01research articlehttp://purl.org/coar/resource_type/c_2df8fbb1AMhttp://purl.org/coar/version/c_ab4af688f83e57aainfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10486/726300https://dx.doi.org/10.1007/s10815-020-02017-9reponame:Biblos-e Archivo. Repositorio Institucional de la UAMinstname:Universidad Autónoma de MadridInglésengopen accesshttp://purl.org/coar/access_right/c_abf2info:eu-repo/semantics/openAccessoai:repositorio.uam.es:10486/7263002026-06-23T12:46:27Z
dc.title.none.fl_str_mv Regulating reproductive genetic services: dealing with spiral-shaped processes and techno-scientific imaginaries
title Regulating reproductive genetic services: dealing with spiral-shaped processes and techno-scientific imaginaries
spellingShingle Regulating reproductive genetic services: dealing with spiral-shaped processes and techno-scientific imaginaries
Alon, Ido
Assisted reproductive technologies
Reproductive genetic services
Diffusion of innovation
Regulating emerging technologies
Delphi
Preimplantation genetic testing
Biología y Biomedicina / Biología
title_short Regulating reproductive genetic services: dealing with spiral-shaped processes and techno-scientific imaginaries
title_full Regulating reproductive genetic services: dealing with spiral-shaped processes and techno-scientific imaginaries
title_fullStr Regulating reproductive genetic services: dealing with spiral-shaped processes and techno-scientific imaginaries
title_full_unstemmed Regulating reproductive genetic services: dealing with spiral-shaped processes and techno-scientific imaginaries
title_sort Regulating reproductive genetic services: dealing with spiral-shaped processes and techno-scientific imaginaries
dc.creator.none.fl_str_mv Alon, Ido
Urbanos Garrido, Rosa
Guimón de Ros, José
author Alon, Ido
author_facet Alon, Ido
Urbanos Garrido, Rosa
Guimón de Ros, José
author_role author
author2 Urbanos Garrido, Rosa
Guimón de Ros, José
author2_role author
author
dc.contributor.none.fl_str_mv Departamento de Estructura Económica y Economía del Desarrollo
Facultad de Ciencias Económicas y Empresariales
dc.subject.none.fl_str_mv Assisted reproductive technologies
Reproductive genetic services
Diffusion of innovation
Regulating emerging technologies
Delphi
Preimplantation genetic testing
Biología y Biomedicina / Biología
topic Assisted reproductive technologies
Reproductive genetic services
Diffusion of innovation
Regulating emerging technologies
Delphi
Preimplantation genetic testing
Biología y Biomedicina / Biología
description Purpose We have been inquiring into the diffusion process of reproductive genetic services (RGS) and the viability of geneticization in human reproduction. Method A 2-round modified-Delphi survey was applied amongst Israeli and Spanish experts to analyze regulatory attitudes and expectations about the future applications of RGS. We argue that an explanation of RGS diffusion based on a ‘technology-push’ impulse should be complemented by a ‘demandpull’ approach, which underscores the importance of regulatory frameworks and demand-inducing policies. The diffusion of RGS is advancing in a ‘spiralshaped’ process where technology acts as a cause and effect simultaneously, modulating social acceptance and redefining the notions of health and responsibility along the way. Results We suggest that there is a ‘grey-zone’ of RGS regulations regarding four procedures: the use of germline genome modification (GGM) for severe monogenic disorders, preimplantation genetic testing (PGT) for detection of chromosomal abnormalities, PGT for multifactorial diseases, and PGT with whole-exome screening. Conclusions Although far from the geneticization of human reproduction, our findings suggest that, since techno-scientific imaginaries tend to shape regulations and thus favor the diffusion of RGS, policymakers should pay attention to those procedures by focusing on good practices and equity while providing sound information on potential risks and expected success rates. A broad and inclusive societal debate is critical for overcoming the difficulty of drawing a clear line between medical and nonmedical uses of genetic selection and engineering while searching for the right balance between allowing reproductive autonomy and protecting the public interest
publishDate 2021
dc.date.none.fl_str_mv 2021
2021-06-01
dc.type.none.fl_str_mv research article
http://purl.org/coar/resource_type/c_2df8fbb1
AM
http://purl.org/coar/version/c_ab4af688f83e57aa
dc.type.openaire.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://hdl.handle.net/10486/726300
https://dx.doi.org/10.1007/s10815-020-02017-9
url https://hdl.handle.net/10486/726300
https://dx.doi.org/10.1007/s10815-020-02017-9
dc.language.none.fl_str_mv Inglés
eng
language_invalid_str_mv Inglés
language eng
dc.rights.none.fl_str_mv open access
http://purl.org/coar/access_right/c_abf2
dc.rights.openaire.fl_str_mv info:eu-repo/semantics/openAccess
rights_invalid_str_mv open access
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Springer
publisher.none.fl_str_mv Springer
dc.source.none.fl_str_mv reponame:Biblos-e Archivo. Repositorio Institucional de la UAM
instname:Universidad Autónoma de Madrid
instname_str Universidad Autónoma de Madrid
reponame_str Biblos-e Archivo. Repositorio Institucional de la UAM
collection Biblos-e Archivo. Repositorio Institucional de la UAM
repository.name.fl_str_mv
repository.mail.fl_str_mv
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