Factors associated with underreporting of adverse drug reactions by patients: a systematic review

Background: Spontaneous reporting is the most used method to monitor post-marketing safety information. Although patient involvement in spontaneous reporting has increased overtime, little is known about factors associated with patients' adverse drug reaction (ADR) reporting. Aim: To identify a...

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Detalhes bibliográficos
Autores: Costa, C., Abeijon, P., Rodrigues, D.A., Figueiras Guzmán, Adolfo, Herdeiro, M.T., Torre, C.
Tipo de documento: artigo
Data de publicação:2023
País:España
Recursos:Servizo Galego de Saúde (SERGAS)
Repositório:RUNA. Repositorio da Consellería de Sanidade e Sergas
OAI Identifier:oai:runa.sergas.gal:20.500.11940/21495
Acesso em linha:https://portalcientifico.sergas.gal//documentos/64860189a219857f1d78b716
http://hdl.handle.net/20.500.11940/21495
Access Level:Acceso aberto
Palavra-chave:Humans
Aged
Surveys and Questionnaires
Adverse Drug Reaction Reporting Systems
Health Knowledge, Attitudes, Practice
Pharmacovigilance
Drug-Related Side Effects and Adverse Reactions
AS Santiago
IDIS
id ES_4fe60a4c24e2fbd6bf14534a64dbff6f
oai_identifier_str oai:runa.sergas.gal:20.500.11940/21495
network_acronym_str ES
network_name_str España
repository_id_str
spelling Factors associated with underreporting of adverse drug reactions by patients: a systematic reviewCosta, C.Abeijon, P.Rodrigues, D.A.Figueiras Guzmán, AdolfoHerdeiro, M.T.Torre, C.HumansAgedSurveys and QuestionnairesAdverse Drug Reaction Reporting SystemsHealth Knowledge, Attitudes, PracticePharmacovigilanceDrug-Related Side Effects and Adverse ReactionsAS SantiagoIDISBackground: Spontaneous reporting is the most used method to monitor post-marketing safety information. Although patient involvement in spontaneous reporting has increased overtime, little is known about factors associated with patients' adverse drug reaction (ADR) reporting. Aim: To identify and assess the sociodemographic characteristics, attitudes and knowledge that influence spontaneous reporting and the reasons associated with ADR underreporting by patients. Method: A systematic review was conducted according to PRISMA guidelines. A search on the MEDLINE and EMBASE scientific databases was performed to retrieve studies published between 1 January 2006 and 1 November 2022. Studies were included if they addressed knowledge and attitudes associated with ADR underreporting. Results: A total of 2512 citations were identified, of which 13 studies were included. Sociodemographic characteristics were frequently identified with ADR reporting in 6 studies, being age (3/13) and level of education (3/13) the most often reported. Older age groups (2/13) and individuals with higher level of education (3/13) were more likely to report ADRs. Underreporting was shown to be motivated by reasons related to knowledge, attitudes, and excuses. Ignorance (10/13), complacency (6/13), and lethargy (6/13) were the most frequent reasons for not reporting. Conclusion: This study highlighted the scarcity of research conducted with the aim of assessing ADR underreporting by patients. Knowledge, attitudes, and excuses were commonly observed in the decision to report ADRs. These motives are characteristics that can be changed; hence strategies must be designed to raise awareness, continually educate, and empower this population to change the paradigm of underreporting.2023info:eu-repo/semantics/articlehttps://portalcientifico.sergas.gal//documentos/64860189a219857f1d78b716http://hdl.handle.net/20.500.11940/21495reponame:RUNA. Repositorio da Consellería de Sanidade e Sergasinstname:Servizo Galego de Saúde (SERGAS)Ingléshttp://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessoai:runa.sergas.gal:20.500.11940/214952026-06-12T08:40:47Z
dc.title.none.fl_str_mv Factors associated with underreporting of adverse drug reactions by patients: a systematic review
title Factors associated with underreporting of adverse drug reactions by patients: a systematic review
spellingShingle Factors associated with underreporting of adverse drug reactions by patients: a systematic review
Costa, C.
Humans
Aged
Surveys and Questionnaires
Adverse Drug Reaction Reporting Systems
Health Knowledge, Attitudes, Practice
Pharmacovigilance
Drug-Related Side Effects and Adverse Reactions
AS Santiago
IDIS
title_short Factors associated with underreporting of adverse drug reactions by patients: a systematic review
title_full Factors associated with underreporting of adverse drug reactions by patients: a systematic review
title_fullStr Factors associated with underreporting of adverse drug reactions by patients: a systematic review
title_full_unstemmed Factors associated with underreporting of adverse drug reactions by patients: a systematic review
title_sort Factors associated with underreporting of adverse drug reactions by patients: a systematic review
dc.creator.none.fl_str_mv Costa, C.
Abeijon, P.
Rodrigues, D.A.
Figueiras Guzmán, Adolfo
Herdeiro, M.T.
Torre, C.
author Costa, C.
author_facet Costa, C.
Abeijon, P.
Rodrigues, D.A.
Figueiras Guzmán, Adolfo
Herdeiro, M.T.
Torre, C.
author_role author
author2 Abeijon, P.
Rodrigues, D.A.
Figueiras Guzmán, Adolfo
Herdeiro, M.T.
Torre, C.
author2_role author
author
author
author
author
dc.subject.none.fl_str_mv Humans
Aged
Surveys and Questionnaires
Adverse Drug Reaction Reporting Systems
Health Knowledge, Attitudes, Practice
Pharmacovigilance
Drug-Related Side Effects and Adverse Reactions
AS Santiago
IDIS
topic Humans
Aged
Surveys and Questionnaires
Adverse Drug Reaction Reporting Systems
Health Knowledge, Attitudes, Practice
Pharmacovigilance
Drug-Related Side Effects and Adverse Reactions
AS Santiago
IDIS
description Background: Spontaneous reporting is the most used method to monitor post-marketing safety information. Although patient involvement in spontaneous reporting has increased overtime, little is known about factors associated with patients' adverse drug reaction (ADR) reporting. Aim: To identify and assess the sociodemographic characteristics, attitudes and knowledge that influence spontaneous reporting and the reasons associated with ADR underreporting by patients. Method: A systematic review was conducted according to PRISMA guidelines. A search on the MEDLINE and EMBASE scientific databases was performed to retrieve studies published between 1 January 2006 and 1 November 2022. Studies were included if they addressed knowledge and attitudes associated with ADR underreporting. Results: A total of 2512 citations were identified, of which 13 studies were included. Sociodemographic characteristics were frequently identified with ADR reporting in 6 studies, being age (3/13) and level of education (3/13) the most often reported. Older age groups (2/13) and individuals with higher level of education (3/13) were more likely to report ADRs. Underreporting was shown to be motivated by reasons related to knowledge, attitudes, and excuses. Ignorance (10/13), complacency (6/13), and lethargy (6/13) were the most frequent reasons for not reporting. Conclusion: This study highlighted the scarcity of research conducted with the aim of assessing ADR underreporting by patients. Knowledge, attitudes, and excuses were commonly observed in the decision to report ADRs. These motives are characteristics that can be changed; hence strategies must be designed to raise awareness, continually educate, and empower this population to change the paradigm of underreporting.
publishDate 2023
dc.date.none.fl_str_mv 2023
dc.type.none.fl_str_mv info:eu-repo/semantics/article
format article
dc.identifier.none.fl_str_mv https://portalcientifico.sergas.gal//documentos/64860189a219857f1d78b716
http://hdl.handle.net/20.500.11940/21495
url https://portalcientifico.sergas.gal//documentos/64860189a219857f1d78b716
http://hdl.handle.net/20.500.11940/21495
dc.language.none.fl_str_mv Inglés
language_invalid_str_mv Inglés
dc.rights.none.fl_str_mv http://creativecommons.org/licenses/by/4.0/
info:eu-repo/semantics/openAccess
rights_invalid_str_mv http://creativecommons.org/licenses/by/4.0/
eu_rights_str_mv openAccess
dc.source.none.fl_str_mv reponame:RUNA. Repositorio da Consellería de Sanidade e Sergas
instname:Servizo Galego de Saúde (SERGAS)
instname_str Servizo Galego de Saúde (SERGAS)
reponame_str RUNA. Repositorio da Consellería de Sanidade e Sergas
collection RUNA. Repositorio da Consellería de Sanidade e Sergas
repository.name.fl_str_mv
repository.mail.fl_str_mv
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score 15,811543

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